Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Michael Lockyer"'
Publikováno v:
Topology and its Applications. 254:85-100
Given compact metric spaces X 1 and X 2 , closed subsets Y 1 and Y 2 of X 1 and X 2 respectively, and an upper semicontinuous function g : Y 1 ⊸ Y 2 , we define a special kind of extension f : X 1 ⊸ X 2 of the function g and prove some of its pro
Publikováno v:
Topology and its Applications. 288:107471
We consider how inverse limits and Mahavier-products of upper semicontinuous functions relate to their bonding functions with respect to indecomposability and connectedness. We show that if such an inverse limit is decomposable then for some n, the M
Autor:
Michael Lockyer, Sina Greenwood
Publikováno v:
Topology and its Applications. 280:107275
Suppose that for each i ≥ 0 , I i = [ 0 , 1 ] and f is an inverse sequence of upper semicontinuous surjective functions f i + 1 : I i + 1 → 2 I i , each with a path-connected graph. We investigate necessary and sufficient conditions for lim ← f
Autor:
C.E. Nichols, Alastair R. Hawkins, Ian G. Charles, Heather K. Lamb, K. El Omari, Paul Thompson, David K. Stammers, Michael Lockyer
Publikováno v:
Protein Science. 22:628-640
YgjD from COG0533 is amongst a small group of highly conserved proteins present in all three domains of life. Various roles and biochemical functions (including sialoprotease and endonuclease activities) have been ascribed to YgjD and orthologs, the
Autor:
Michael Lockyer, Sina Greenwood
Publikováno v:
Topology and its Applications. 160(3):513-523
Suppose that for each i⩾0, Xi is a Hausdorff continuum, and fi+1:Xi+1→2Xi is an upper semicontinuous function with a connected graph Gi+1, such that πi(Gi+1)=Xi and πi+1(Gi+1)=Xi+1 (πi and πi+1 denote the respective projections of Gi+1 to Xi
Autor:
Alastair R. Hawkins, Michael Lockyer, Jingshan Ren, Heather K. Lamb, David K. Stammers, Masayo Kotaka
GTP cyclohydrolase II converts GTP to 2,5-diamino-6-beta-ribosyl-4(3H)-pyrimidinone 5'-phosphate, formate and pyrophosphate, the first step in riboflavin biosynthesis. The essential role of riboflavin in metabolism and the absence of GTP cyclohydrola
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6314045b1a3bf7fff242481d4f5a883f
https://ora.ox.ac.uk/objects/uuid:3fc79a5b-cddf-419f-80c7-c4e8953aa8e2
https://ora.ox.ac.uk/objects/uuid:3fc79a5b-cddf-419f-80c7-c4e8953aa8e2
Autor:
Jingshan Ren, Kenneth L. Powell, Michael Lockyer, Nicola G. A. Abrescia, B. Dhaliwal, K. El Omari, Alastair R. Hawkins, David K. Stammers
Respiratory syncytial virus (RSV) is a frequent cause of respiratory illness in infants, but there is currently no vaccine nor effective drug treatment against this virus. The RSV RNA genome is encapsidated and protected by a nucleocapsid protein; th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fdeda3070740daee24527bfe2773bdc
https://doi.org/10.1107/s1744309111029228
https://doi.org/10.1107/s1744309111029228
Two high-resolution structures have been determined for Eschericia coli aspartate beta-semialdehyde dehydrogenase (ecASADH), an enzyme of the aspartate biosynthetic pathway, which is a potential target for novel antimicrobial drugs. Both ASADH struct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::917ff9812b598ab6cfadcc84fc88123b
https://doi.org/10.1016/j.jmb.2004.05.073
https://doi.org/10.1016/j.jmb.2004.05.073
Autor:
A.R. Hawkins, David K. Stammers, Heather K. Lamb, C.E. Nichols, Michael Lockyer, Ian G. Charles, Paul J. Owen, Anna Stamp, Kamel El Omari
Publikováno v:
Protein Science. 19:1897-1905
YcbL has been annotated as either a metallo-β-lactamase or glyoxalase II (GLX2), both members of the zinc metallohydrolase superfamily, that contains many enzymes with a diverse range of activities. Here, we report crystallographic and biochemical d
Publikováno v:
Journal of Biological Chemistry. 281:31544-31552