Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Michael Lietz"'
Autor:
Jason R Chan, Gregory Vuillaume, Caitlin Bever, Stefan Lebrun, Michael Lietz, Yvonne Steffen, Katrin Stolle, Karim Wahba, Xiao Wang, Shonna Moodie, Julia Hoeng, Manuel C Peitsch, Lyn M Powell
Publikováno v:
BioDiscovery, Vol 3, Iss , Pp 1-13 (2012)
Motivation:Atherosclerosis is a complex multi-pathway inflammatory disease where accumulation of oxidatively modified lipids and leukocytes in the arterial intima leads to plaque formation over time. Translating Apoe-/- mouse results to the clinical
Externí odkaz:
https://doaj.org/article/e87ffa701b074622a23a688c4c0f1401
Autor:
Kris Meurrens, Julia Hoeng, Jutta Schueller, Walter K. Schlage, Yvonne Steffen, Hector De Leon, Stefan Lebrun, Michael Lietz, Manuel C. Peitsch, Stéphanie Boué, Gregory Vuillaume, Patrick Vanscheeuwijck, An Berges, Michaela Moehring, Katrin Stolle
Publikováno v:
Atherosclerosis. 229(1):86-93
Tobacco smoke exerts perturbations on lipid metabolism and arterial cell function that accelerate atherosclerosis. Lipidomics has emerged as a key technology in helping to elucidate the lipid-related mechanisms of atherosclerosis. In this study, we i
Autor:
Yvonne Steffen, Gregory Vuillaume, Thomas Wallerath, Jutta Schueller, Katrin Stolle, Karin Roewer, Stefan Lebrun, Michael Lietz
Publikováno v:
Nitric Oxide. 27:176-184
The ubiquitous free radical nitric oxide (NO) plays an important role in many biological processes, including the regulation of both vascular tone and inflammatory response; however, its role in the effects of cigarette smoke exposure on atherosclero
Publikováno v:
Toxicology Letters. 199:403-409
Cigarette smoke, hyperlipidemia, and hypertension with the risk of development and progression of atherosclerosis and associated pathologies such as abdominal aortic aneurysm (AAA) are correlated. We examined the interaction of cigarette mainstream s
Autor:
Alma Zernecke, Thomas Baltus, Andreas Schober, Christian Weber, Line Fraemohs, Michael Lietz, Elisa A. Liehn, Georg Ostermann
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 25:729-735
Objective—The junctional adhesion molecule (JAM)-A on endothelium contributes to the inflammatory recruitment of mononuclear cells involving engagement of its integrin receptor lymphocyte function-associated antigen (LFA)-1. It is unknown whether t
Publikováno v:
European Journal of Biochemistry. 271:2855-2862
Research on the regulation of transcription in mammals initially focused on the mechanism of transcriptional activation and 'positive control' of gene regulation. In contrast, transcriptional repression and 'negative control' of gene transcription wa
Autor:
Wolfgang Erl, Christian Weber, Ute Zeiffer, Elisa A. Liehn, Andreas Schober, Michael Lietz, Neil Emans, Zhong-qun Yan
Publikováno v:
Circulation Research. 94:776-784
Leukocyte recruitment is crucial for the response to vascular injury in spontaneous and accelerated atherosclerosis. Whereas the mechanisms of leukocyte adhesion to endothelium or matrix-bound platelets have been characterized, less is known about th
Publikováno v:
Circulation. 108:2491-2497
Background—Recent evidence indicates that stromal cell–derived factor-1α (SDF-1α) is expressed in human atherosclerotic plaques, whereas high plasma levels are clinically associated with stable coronary artery disease. Herein, we investigate th
Publikováno v:
European Journal of Biochemistry. 270:2-9
Synaptophysin, one of the major proteins on synaptic vesicles, is ubiquitously expressed throughout the brain. Synaptophysin and synapsin I, another synaptic vesicle protein, are also expressed by retinoic acid-induced neuronally differentiated P19 t
Publikováno v:
European Journal of Neuroscience. 14:1303-1312
The zinc finger protein RE-1 silencing transcription factor (REST) is a transcriptional repressor that represses neuronal genes in non-neuronal tissues. We have analyzed the ability of REST and the REST mutants, RESTDeltaN and RESTDeltaC lacking eith