Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Michael Lidschreiber"'
Autor:
Rui Shao, Banushree Kumar, Katja Lidschreiber, Michael Lidschreiber, Patrick Cramer, Simon J Elsässer
Publikováno v:
Molecular Systems Biology, Vol 18, Iss 1, Pp 1-19 (2022)
Abstract Mouse embryonic stem cells (mESCs) can adopt naïve, ground, and paused pluripotent states that give rise to unique transcriptomes. Here, we use transient transcriptome sequencing (TT‐seq) to define both coding and non‐coding transcripti
Externí odkaz:
https://doaj.org/article/2de88ef7f29d4451b293ebf8ca0516d6
Autor:
Katja Lidschreiber, Lisa A Jung, Henrik von der Emde, Kashyap Dave, Jussi Taipale, Patrick Cramer, Michael Lidschreiber
Publikováno v:
Molecular Systems Biology, Vol 17, Iss 1, Pp 1-23 (2021)
Abstract The growth of human cancer cells is driven by aberrant enhancer and gene transcription activity. Here, we use transient transcriptome sequencing (TT‐seq) to map thousands of transcriptionally active putative enhancers in fourteen human can
Externí odkaz:
https://doaj.org/article/f9845d94031942ae8a720cdf29e6f3fa
Oct4 differentially regulates chromatin opening and enhancer transcription in pluripotent stem cells
Autor:
Le Xiong, Erik A Tolen, Jinmi Choi, Sergiy Velychko, Livia Caizzi, Taras Velychko, Kenjiro Adachi, Caitlin M MacCarthy, Michael Lidschreiber, Patrick Cramer, Hans R Schöler
Publikováno v:
eLife, Vol 11 (2022)
The transcription factor Oct4 is essential for the maintenance and induction of stem cell pluripotency, but its functional roles are not fully understood. Here, we investigate the functions of Oct4 by depleting and subsequently recovering it in mouse
Externí odkaz:
https://doaj.org/article/1d5965331e63415ea1891c5a5bf6e818
Autor:
Gert-Jan Hendriks, Lisa A. Jung, Anton J. M. Larsson, Michael Lidschreiber, Oscar Andersson Forsman, Katja Lidschreiber, Patrick Cramer, Rickard Sandberg
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
Sequencing of newly synthesised RNA can reveal the transcriptional dynamics in a population of cells. Here the authors develop NASC-seq to bring this sensitivity and temporal resolution to single-cell analysis.
Externí odkaz:
https://doaj.org/article/6c2539c49151440bae8f5d6aea33b041
Autor:
Julio Abril-Garrido, Christian Dienemann, Frauke Grabbe, Taras Velychko, Michael Lidschreiber, Haibo Wang, Patrick Cramer
Publikováno v:
Molecular Cell.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b088fbe65b30141ea39d9a05deaac08
https://doi.org/10.1016/j.molcel.2023.04.011
https://doi.org/10.1016/j.molcel.2023.04.011
Autor:
Sofia Battaglia, Michael Lidschreiber, Carlo Baejen, Phillipp Torkler, Seychelle M Vos, Patrick Cramer
Publikováno v:
eLife, Vol 6 (2017)
For transcription through chromatin, RNA polymerase (Pol) II associates with elongation factors (EFs). Here we show that many EFs crosslink to RNA emerging from transcribing Pol II in the yeast Saccharomyces cerevisiae. Most EFs crosslink preferentia
Externí odkaz:
https://doaj.org/article/e7db3bfd4b324548acadfae3d2e47a88
Autor:
Erik A Tolen, Le Xiong, Jinmi Choi, Sergiy Velychko, Livia Caizzi, Taras Velychko, Kenjiro Adachi, Caitlin M MacCarthy, Michael Lidschreiber, Patrick Cramer, Hans R Schöler
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca9e19f99e30a5e867714e090f2dbfe3
https://doi.org/10.7554/elife.71533.sa2
https://doi.org/10.7554/elife.71533.sa2
Autor:
Biswajyoti Sahu, Tuomo Hartonen, Päivi Pihlajamaa, Bei Wei, Kashyap Dave, Fangjie Zhu, Eevi Kaasinen, Katja Lidschreiber, Michael Lidschreiber, Carsten O. Daub, Patrick Cramer, Teemu Kivioja, Jussi Taipale
Publikováno v:
Nature Genetics
Funder: Sigrid Juséliuksen Säätiö (Sigrid Jusélius Foundation); doi: https://doi.org/10.13039/501100006306
Funder: Jane ja Aatos Erkon Säätiö (Jane and Aatos Erkko Foundation); doi: https://doi.org/10.13039/501100004012
Funder: Syö
Funder: Jane ja Aatos Erkon Säätiö (Jane and Aatos Erkko Foundation); doi: https://doi.org/10.13039/501100004012
Funder: Syö
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a921b9355f20739b39b8d1b6f0a9a6f
Oct4 differentially regulates chromatin opening and enhancer transcription in pluripotent stem cells
Autor:
Erik A Tolen, Le Xiong, Jinmi Choi, Sergiy Velychko, Livia Caizzi, Taras Velychko, Kenjiro Adachi, Caitlin M MacCarthy, Michael Lidschreiber, Patrick Cramer, Hans R Schöler
Publikováno v:
eLife.
eLife
eLife
The transcription factor Oct4 is essential for the maintenance and induction of stem cell pluripotency, but its functional roles are not fully understood. Here, we investigate the functions of Oct4 by depleting and subsequently recovering it in mouse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2eaac64b427e19cd7c4d74173e3c76aa
Autor:
Patrick Cramer, Hans R. Schöler, Xiong L, K. Adachi, Michael Lidschreiber, Jinmi Choi, Livia Caizzi, Tolen Ea
The transcription factor Oct4 is essential for maintaining stem cell pluripotency and for efficient cell reprogramming, but its functional roles are far from being understood. Here, we investigate the functions of Oct4 by rapidly depleting Oct4 from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5affce783b663315a63184bb88cf0cc0
https://doi.org/10.1101/2021.06.28.450119
https://doi.org/10.1101/2021.06.28.450119