Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Michael Leuck"'
Publikováno v:
Nucleosides, Nucleotides & Nucleic Acids. 24:989-992
The synthesis of a novel amino-ON CPG support and its application in the synthesis of 3'-aminoalkylated oligonucleotides is reported. The release of oligonucleotides with free 3'-amino groups is accomplished by treatment with concentrated ammonia for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62e5744c07c1db417d6714783f64f2ce
https://doi.org/10.1081/ncn-200059388
https://doi.org/10.1081/ncn-200059388
Publikováno v:
Tetrahedron Letters. 45:317-320
A novel improved controlled pore glass (CPG) support based on the 2-(hydroxymethyl)-6-nitrobenzoyl (HMNB) protecting group was developed for the synthesis of 3′-aminoalkylated oligonucleotides. The release of oligonucleotides with free 3′-amino g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd3ef749e44538fe405f8987f4a5ebd8
https://doi.org/10.1016/j.tetlet.2003.10.166
https://doi.org/10.1016/j.tetlet.2003.10.166
Autor:
Kurt Vagle, Michael Leuck, Ken Hill, Jeffrey D. Carter, Jon Taunton-Rigby, Danny P. C. McGee, Dominic J. Anziano, David P. Sebesta, Wolfgang Pieken, Gregory M. Husar, Eric Kropp
Publikováno v:
The Journal of Organic Chemistry. 66:5352-5358
In an effort to offer complementary technology for covalent biomolecule modification (bioconjugation), we have developed a method that exploits the aqueous acceleration of Diels--Alder reactions for this purpose. Three different diene phosphoramidite
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6d246810c2e923405baf23895dc34ac
https://doi.org/10.1021/jo0100190
https://doi.org/10.1021/jo0100190
Publikováno v:
Nucleosides, Nucleotides and Nucleic Acids. 20:559-566
The importance of chemically modified and surface immobilized nucleic acids has inspired the development of a wide variety of complementary techniques for covalent oligonucleotide preparation and immobilization. We are developing technology based on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54a9df25943083fb27c877ea6106b5a5
https://doi.org/10.1081/ncn-100002332
https://doi.org/10.1081/ncn-100002332
Autor:
Michael Leuck, Horst Kunz
Publikováno v:
Carbohydrate Research. 312:33-44
α - l -Rhamnosides of 4-hydroxy-benzyl compounds with nitrile, carbamate, and thiocarbamate groups occurring in Moringa oleifera leaf extracts and the α - l -rhamnoside of anisaldehyde derivatives were synthesised. Electrophilic activation of S -pe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf4a4312bfc80681761bc4cedf30caf6
https://doi.org/10.1016/s0008-6215(98)00223-7
https://doi.org/10.1016/s0008-6215(98)00223-7
Autor:
Michael Leuck, Horst Kunz
Publikováno v:
Journal für Praktische Chemie/Chemiker-Zeitung. 339:322-334
The synthesis of glycopeptides 34 and 38 with tumor associated TN and T antigen structure containing a partial sequence of the tandem repeat unit of the polymorphic epithelial mucin MUC-1 were achieved via fragment condensations. Electrophilic activa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f7daef64d39118787319bbe6f28cca04
https://doi.org/10.1002/prac.19973390160
https://doi.org/10.1002/prac.19973390160
Publikováno v:
Nucleosides, Nucleotides and Nucleic Acids. 22:1495-1497
The synthesis of cyclohexadiene and maleimide derivatives and their use for the functionalization of oligonucleotides and the coating of glass surfaces is reported. A method for the covalent attachment of diene or maleimide modified oligonucleotides
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2733028aeeecda5842b547263e27b78
https://doi.org/10.1081/ncn-120023019
https://doi.org/10.1081/ncn-120023019
Autor:
Horst Kunz, Michael Leuck
Publikováno v:
ChemInform. 28
The synthesis of glycopeptides 34 and 38 with tumor associated TN and T antigen structure containing a partial sequence of the tandem repeat unit of the polymorphic epithelial mucin MUC-1 were achieved via fragment condensations. Electrophilic activa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd09e3d1aaa1ac7c6cdec10c8ebc9f7f
https://doi.org/10.1002/chin.199735245
https://doi.org/10.1002/chin.199735245
Autor:
Michael Leuck, Horst Kunz
Publikováno v:
ChemInform. 30
α - l -Rhamnosides of 4-hydroxy-benzyl compounds with nitrile, carbamate, and thiocarbamate groups occurring in Moringa oleifera leaf extracts and the α - l -rhamnoside of anisaldehyde derivatives were synthesised. Electrophilic activation of S -pe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce7cade9b8e50bac43c261e56a9046f3
https://doi.org/10.1002/chin.199910215
https://doi.org/10.1002/chin.199910215
Publikováno v:
ChemInform. 32
The importance of chemically modified and surface immobilized nucleic acids has inspired the development of a wide variety of complementary techniques for covalent oligonucleotide preparation and immobilization. We are developing technology based on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d1e2ea00164cdb45c15c2fc3c1a1ff7
https://doi.org/10.1002/chin.200147209
https://doi.org/10.1002/chin.200147209