Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Michael Lehnert"'
Autor:
Maximilian Neugebauer, Clara E. Grundmann, Michael Lehnert, Felix von Stetten, Susanna M. Früh, Regine Süss
Publikováno v:
Pharmaceutics, Vol 14, Iss 7, p 1348 (2022)
RNA interference (RNAi) is a powerful therapeutic approach for messenger RNA (mRNA) level regulation in human cells. RNAi can be triggered by small interfering RNAs (siRNAs) which are delivered by non-viral carriers, e.g., dendriplexes. siRNA quantif
Externí odkaz:
https://doaj.org/article/3476219801744b6681a1dbe1d841e74d
Autor:
Yu-Ting Kao, Silvia Calabrese, Nadine Borst, Michael Lehnert, Yu-Kai Lai, Franziska Schlenker, Peter Juelg, Roland Zengerle, Piotr Garstecki, Felix von Stetten
Publikováno v:
Biosensors, Vol 12, Iss 4, p 237 (2022)
We demonstrate detection and quantification of bacterial load with a novel microfluidic one-pot wash-free fluorescence in situ hybridization (FISH) assay in droplets. The method offers minimal manual workload by only requiring mixing of the sample wi
Externí odkaz:
https://doaj.org/article/9e70d71d2f3147bb814191c5892ebf6b
Autor:
Simon Wadle, Michael Lehnert, Friedrich Schuler, René Köppel, Annerose Serr, Roland Zengerle, Felix von Stetten
Publikováno v:
BioTechniques, Vol 61, Iss 3, Pp 123-128 (2016)
Mediator probe (MP) PCR is a real-time PCR approach that uses standardized universal fluorogenic reporter oligonucleotides (UR) in conjunction with label-free sequence-specific probes. To enable multiplex real-time MP PCR, we designed a set of five o
Externí odkaz:
https://doaj.org/article/f4d9af57eaa7470fabf45325be843c3f
Autor:
Nils Paust, Tobias Hutzenlaub, Roland Zengerle, Michael Lehnert, Felix von Stetten, Peter Juelg, Cornelia Eckert, Elena Kipf, Mara Specht, Mark Keller
Publikováno v:
Lab on a Chip. 19:2205-2219
We introduce a new concept for centrifugal microfluidics that enables fully automated serial dilution generation without any additional means besides temperature control. The key feature is time-independent, serial valving of mixing chambers by fill-
Autor:
Erik Michael Lehnert, Virginia eWalbot
Publikováno v:
Frontiers in Plant Science, Vol 5 (2014)
Dahlia variabilis, with an exceptionally high diversity of floral forms and colors, is a popular flower amongst both commercial growers and hobbyists. Recently, some genetic controls of pigment patterns have been elucidated. These studies have been l
Externí odkaz:
https://doaj.org/article/2c4f61f6c3b3466c888584db46a285d5
Autor:
Tobias Hutzenlaub, Michael Lehnert, Elena Kipf, Cornelia Eckert, Peter Juelg, Roland Zengerle, Marion Fillies, Nils Paust, Mara Specht
Publikováno v:
Lab on a chip. 21(3)
We present a proof-of-principle study on automated, highly sensitive and multiplexed qPCR quantification by centrifugal microfluidics. The MRD disk can be used for standardisation of repetitive, longitudinal assays with high requirements on reproduci
Autor:
Matthias Epple, Michael Lehnert, Michael Veith, Volker Ettelt, Alice Belitsky, Angelika Prof. Dr. Loidl-Stahlhofen
Publikováno v:
Journal of Biomedical Materials Research Part A. 106:2910-2922
Increasing cell adhesion on implant surfaces is an issue of high biomedical importance. Early colonization with endogenous cells reduces the risk of bacterial contamination and enhances the integration of an implant into the diverse cellular tissues
Autor:
Michael Lehnert
Le usiamo per afferrare, nutrirci, scrivere, digitare, costruire, abbracciare e accarezzare: le nostre mani sono una delle parti più importanti del nostro corpo. Sono però anche esposte a rischi particolari, perché le utilizziamo costantemente, pe
Publikováno v:
Biomolecular Detection and Quantification
Biomolecular Detection and Quantification, Vol 7, Iss C, Pp 1-8 (2016)
Biomolecular Detection and Quantification, Vol 7, Iss C, Pp 1-8 (2016)
Graphical abstract
Highlights • Design of experiments (DOE) is an appropriate approach for probe sequence optimization in real-time PCR. • Nine MP designs led to maximum information for the 3 input factors. • Using DOE the maximum number o
Highlights • Design of experiments (DOE) is an appropriate approach for probe sequence optimization in real-time PCR. • Nine MP designs led to maximum information for the 3 input factors. • Using DOE the maximum number o