Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Michael Leane"'
Autor:
John F. Gamble, Ilgaz Akseli, Ana P. Ferreira, Michael Leane, Stephen Thomas, Mike Tobyn, Robert C. Wadams
Publikováno v:
International Journal of Pharmaceutics. 635:122743
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff3df71fc5afceeb5bd2c464ddbf9b85
https://doi.org/10.1016/j.ijpharm.2023.122743
https://doi.org/10.1016/j.ijpharm.2023.122743
Autor:
Amin Farshchi, Hervé Barjat, Stephen Checkley, Michael Leane, Mike Tobyn, Chris Morris, Furqan Tahir, Richard Anthony Storey, John F. Gamble, Toma Chitu, Neil Dawson, Andy Mitchell, Ana Patricia Ferreira, Kendal Pitt
Publikováno v:
Journal of Pharmaceutical Innovation. 16:181-196
Understanding and predicting the flow of bulk pharmaceutical materials could be key in enabling pharmaceutical manufacturing by continuous direct compression (CDC). This study examines whether, by taking powder and bulk measurements, and using statis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5934f75aee0af4cfdec854ab8551253b
https://doi.org/10.1007/s12247-020-09433-5
https://doi.org/10.1007/s12247-020-09433-5
Autor:
Michael Leane, Kendal Pitt, Gavin K. Reynolds, Neil Dawson, Iris Ziegler, Aniko Szepes, Abina M. Crean, Rafaela Dall Agnol, null The Manufacturing Classification Sy
Publikováno v:
Pharmaceutical Development and Technology. 23:964-977
Following the first Manufacturing Classification System (MCS) paper, the team conducted surveys to establish which active pharmaceutical ingredient (API) properties were important when selecting or modifying materials to enable an efficient and robus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10478e98d1fa425a86dc5a2d3fe2b1e5
https://doi.org/10.1080/10837450.2018.1534863
https://doi.org/10.1080/10837450.2018.1534863
Autor:
Ronald Sinclair, Eric Schwarz, Barry J. Richardson, M. Kennedy, Katherine E. Moseby, Stuart C. Brown, Peter Elsworth, John H. Matthews, Michael Leane, Tarnya E. Cox, Miguel Lurgi, Damien A. Fordham, Susan Campbell, John Kovaliski, John L. Read, Phill Cassey, Trish Mooney, David Peacock, Iain Dunk, Camille Mellin, Kathryn Schneider, Greg Hocking, Don Fletcher, Tanja Strive, S. R. McPhee, Brian Cooke, Joanne C. Daly, Frédérik Saltré, Dave Berman, Emilie Roy-Dufresne, Barry W. Brook, Greg Mutze, Frank Triulcio, David M. Forsyth, Bill Low, Peter West, Konstans Wells
Publikováno v:
Ecology
Ecology, 2019, 100 (7), ⟨10.1002/ecy.2750⟩
Ecology, Ecological Society of America, 2019, 100 (7), ⟨10.1002/ecy.2750⟩
Ecology, 2019, 100 (7), ⟨10.1002/ecy.2750⟩
Ecology, Ecological Society of America, 2019, 100 (7), ⟨10.1002/ecy.2750⟩
International audience; With ongoing introductions into Australia since the 1700s, the European rabbit (Oryctolagus cuniculus) has become one of the most widely distributed and abundant vertebrate pests, adversely impacting Australia's biodiversity a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88f6f0e1a2b0c85498e89f8b64089725
https://cronfa.swan.ac.uk/Record/cronfa49895
https://cronfa.swan.ac.uk/Record/cronfa49895
Autor:
Clive J. Roberts, George Crull, Michael Leane, Sandra Rutherford, Mike Tobyn, Gao Qi, Helen Hughes, Josh D. Engstrom, Matt Bunker, Andrew Parker, John F. Gamble, Jonathan Brown
Publikováno v:
Journal of Pharmaceutical Sciences. 102:4375-4383
An analysis of the free acid form of the HIV-1 attachment inhibitor prodrug BMS-663068-01 revealed a reversible moisture sorption event in the 42%–46% relative humidity (RH) range. An existing single-crystal analysis indicated that these observatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15b9a72fc07fa5b3ef17abf09ab2b04b
https://doi.org/10.1002/jps.23747
https://doi.org/10.1002/jps.23747
Publikováno v:
International Journal of Pharmaceutics. 445:39-46
The aim of this study was to investigate the applicability of surface energy characterization tools such as inverse gas chromatography for the analysis of binary systems. Drug substance was coated with two grades of silicon dioxide and the surface en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b0760eedc686fa3f250e3fe3a0ecf78
https://doi.org/10.1016/j.ijpharm.2013.01.061
https://doi.org/10.1016/j.ijpharm.2013.01.061
Autor:
Peter Timmins, Mojtaba Ghadiri, Helen Hughes, Afsheen Zarrebini, Enes Šupuk, Jay Poorna Reddy, Mike Tobyn, Michael Leane
Publikováno v:
Powder Technology. 217:427-434
Blending of active pharmaceutical ingredient (API) and excipients is a pre-requisite to the dry manufacture of solid dosage forms intended for oral use, whether or not granulation steps are employed prior to compaction. Excipients and API are known t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ba9cd8361cc279a2f5cf26aff79899d
https://doi.org/10.1016/j.powtec.2011.10.059
https://doi.org/10.1016/j.powtec.2011.10.059
Autor:
Andrew B. Dennis, Wayne Sinclair, Haddadin Raja M, Mike Tobyn, Michael Leane, Feng Qian, Alan Brown
Publikováno v:
Pharmaceutical Development and Technology. 18:359-366
Amorphous forms of poorly soluble drugs are more frequently being incorporated into solid dispersions for administration and extensive research has led to a reasonable understanding of how these dispersions, although still kinetically unstable, impro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6703da4f82a50b1a8e8c1d1a3d590c0
https://doi.org/10.3109/10837450.2011.619544
https://doi.org/10.3109/10837450.2011.619544
Autor:
Dolapo Olusanmi, John F. Gamble, Mike Tobyn, Majid Naderi, Jiyi Khoo, Michael Leane, Enes Šupuk
Publikováno v:
International Journal of Pharmaceutics. 422:238-244
This study investigates the impact of micronization on the measured surface energy characteristics of an active pharmaceutical ingredient (API), Ibipinabant, by inverse gas chromatography (IGC) using both a fixed probe concentration, commonly used in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d70ab2dac153bf9b3b9f5d8a3a7579c
https://doi.org/10.1016/j.ijpharm.2011.11.002
https://doi.org/10.1016/j.ijpharm.2011.11.002
Publikováno v:
Journal of Pharmaceutical Sciences. 100:4687-4699
The solid-state physical stability and recrystallization kinetics during storage stability are described for an amorphous solid dispersed drug substance, ibipinabant, at a low concentration (1.0%, w/w) in a solid oral dosage form (tablet). The recrys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::776a14ed4ef9892fc78203f60900f634
https://doi.org/10.1002/jps.22658
https://doi.org/10.1002/jps.22658