Reducing saturated fat intake lowers LDL-C but increases Lp(a) levels in African Americans: the GET-READI feeding trial

Autor: Hayley G. Law, Muhammad A. Khan, Wei Zhang, Heejung Bang, Jennifer Rood, Marlene Most, Michael Lefevre, Lars Berglund, Byambaa Enkhmaa

Publikováno v: Journal of Lipid Research, Vol 64, Iss 9, Pp 100420- (2023)

Reducing dietary saturated fatty acids (SFA) intake results in a clinically significant lowering of low-density lipoprotein cholesterol (LDL-C) across ethnicities. In contrast, dietary SFA’s role in modulating emerging cardiovascular risk factors i

Externí odkaz: https://doaj.org/article/c12c068748c646fcb58d1a34e277abaa

No effect of a dairy-based, high flavonoid pre-workout beverage on exercise-induced intestinal injury, permeability, and inflammation in recreational cyclists: A randomized controlled crossover trial.

Autor: Stephanie Kung, Michael N Vakula, Youngwook Kim, Derek L England, Janet Bergeson, Eadric Bressel, Michael Lefevre, Robert Ward

Publikováno v: PLoS ONE, Vol 17, Iss 11, p e0277453 (2022)

BackgroundSubmaximal endurance exercise has been shown to cause elevated gastrointestinal permeability, injury, and inflammation, which may negatively impact athletic performance and recovery. Preclinical and some clinical studies suggest that flavon

Externí odkaz: https://doaj.org/article/39157916acff4d4a9287a41b3af88453

Differential response to low-fat diet between low and normal HDL-cholesterol subjects

Autor: Bela Asztalos, Michael Lefevre, Laurence Wong, Theda A. Foster, Richard Tulley, Marlene Windhauser, Wenwu Zhang, Paul S. Roheim

Publikováno v: Journal of Lipid Research, Vol 41, Iss 3, Pp 321-328 (2000)

Abstract: Heart attacks frequently occur in normolipidemic subjects with low concentration of high density lipoproteins (≤35 mg/dL). A low-fat diet is generally recommended to patients with coronary heart disease. A low-fat diet decreases both low

Externí odkaz: https://doaj.org/article/944ae65cb2f846cd87d2107e5979565d

Effect of Choline Forms and Gut Microbiota Composition on Trimethylamine-N-Oxide Response in Healthy Men

Autor: Michael Lefevre, Clara E. Cho, Niklas D J Aardema, Marie A. Caudill, Madison L Bunnell, Janet R Bergeson, Deanna Larson, Olga V. Malysheva, Sheryl S. Aguilar

Publikováno v: Nutrition, Dietetics, and Food Sciences Faculty Publications
Nutrients
Nutrients, Vol 12, Iss 2220, p 2220 (2020)
Volume 12
Issue 8

Background: Trimethylamine-N-oxide (TMAO), a choline-derived gut microbiota-dependent metabolite, is a newly recognized risk marker for cardiovascular disease. We sought to determine: (1) TMAO response to meals containing free versus lipid-soluble ch

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14cec0d80a16924f801448b4eed8703d
https://digitalcommons.usu.edu/cgi/viewcontent.cgi?article=1920&context=nfs_facpub

The Type and Amount of Dietary Fat Affect Plasma Factor VIIc, Fibrinogen, and PAI-1 in Healthy Individuals and Individuals at High Cardiovascular Disease Risk: 2 Randomized Controlled Trials

Autor: Penny M Kris-Etherton, Paul W Stewart, Henry N Ginsberg, Russell P Tracy, Michael Lefevre, Patricia J Elmer, Lars Berglund, Abby G Ershow, Thomas A Pearson, Rajasekhar Ramakrishnan, Stephen F Holleran, Barbara H Dennis, Catherine M Champagne, Wahida Karmally, Henry Ginsberg, Maliha Siddiqui, Niem-Tzu Chen, Steve Holleran, Colleen Johnson, Roberta Holeman, Karen Chirgwin, Kellye Stennett, Lencey Ganga, Tajsudeen Towolawai, Minnie Myers, Colleen Ngai, Nelson Fontenez, Jeff Jones, Carmen Rodriguez, Norma Useche, Paul S Roheim, Donna Ryan, Marlene Most, Catherine Champagne, Donald Williamson, Richard Tulley, Ricky Brock, Deonne Bodin, Betty Kennedy, Michelle Barkate, Elizabeth Foust, Deshoin York, Penny Kris-Etherton, Satya Jonnalagadda, Janice Derr, Abir Farhat-Wood, Vikkie Mustad, Kate Meaker, Edward Mills, Mary-Ann Tilley, Helen Smiciklas-Wright, Madeleine Sigman-Grant, Shaomei Yu, Jean-Xavier Guinard, Pamela Sechevich, C Channa Reddy, Andrea M Mastro, Allen D Cooper, Patricia Elmer, Aaron Folsom, Nancy Van Heel, Christine Wold, Kay Fritz, Joanne Slavin, David Jacobs, Barbara Dennis, Paul Stewart, C Davis, James Hosking, Nancy Anderson, Susan Blackwell, Lynn Martin, Hope Bryan, W Brian Stewart, Jeffrey Abolafia, Malachy Foley, Conroy Zien, Szu-Yun Leu, Marston Youngblood, Thomas Goodwin, Monica Miles, Jennifer Wehbie, Thomas Pearson, Roberta Reed, Russell Tracy, Elaine Cornell, Kent Stewart, Katherine Phillips, Bernestine McGee, Brenda Williams, Gary Beecher, Joanne Holden, Carol Davis, Abby Ershow, David Gordon, Michael Proschan, Basil Rifkind

Publikováno v: J Nutr

BACKGROUND: Factor VIIc, fibrinogen, and plasminogen activator inhibitor 1 (PAI-1) are cardiovascular disease (CVD) risk factors and are modulated, in part, by fat type and amount. OBJECTIVE: We evaluated fat type and amount on the primary outcomes:

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a4bcb6c360fea57f94d6a298f06b013
https://pubmed.ncbi.nlm.nih.gov/32492148