Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Michael Lamm"'
Autor:
Leonie G. Graf, Carlos Moreno-Yruela, Chuan Qin, Sabrina Schulze, Gottfried J. Palm, Ole Schmöker, Nancy Wang, Dianna M. Hocking, Leila Jebeli, Britta Girbardt, Leona Berndt, Babett Dörre, Daniel M. Weis, Markus Janetzky, Dirk Albrecht, Daniela Zühlke, Susanne Sievers, Richard A. Strugnell, Christian A. Olsen, Kay Hofmann, Michael Lammers
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-31 (2024)
Abstract Classical Zn2+-dependent deac(et)ylases play fundamental regulatory roles in life and are well characterized in eukaryotes regarding their structures, substrates and physiological roles. In bacteria, however, classical deacylases are less we
Externí odkaz:
https://doaj.org/article/ccf2c27a6704404393014ebb3e735864
Autor:
Chuan Qin, Leonie G. Graf, Kilian Striska, Markus Janetzky, Norman Geist, Robin Specht, Sabrina Schulze, Gottfried J. Palm, Britta Girbardt, Babett Dörre, Leona Berndt, Stefan Kemnitz, Mark Doerr, Uwe T. Bornscheuer, Mihaela Delcea, Michael Lammers
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-22 (2024)
Abstract The AMP-forming acetyl-CoA synthetase is regulated by lysine acetylation both in bacteria and eukaryotes. However, the underlying mechanism is poorly understood. The Bacillus subtilis acetyltransferase AcuA and the AMP-forming acetyl-CoA syn
Externí odkaz:
https://doaj.org/article/dc277252131d4568afb2aac51547d6c8
Autor:
Tamara Janker, Adrian Brun, Adrian Sievers-Engler, Kristina Dittrich, Meinrad Gawaz, Michael Lämmerhofer
Publikováno v:
Journal of Chromatography Open, Vol 6, Iss , Pp 100160- (2024)
In a recent untargeted clinical lipidomics study of platelets of coronary artery disease (CAD) patients, medium-chain phosphatidylcholines (MCPCs) with C8 and C10 fatty acyl residues were found significantly upregulated in the patient group with acut
Externí odkaz:
https://doaj.org/article/7712b110674344cc8d6cc146eb3e16ee
Autor:
Arnaud Kengmo Tchoupa, Ahmed M. A. Elsherbini, Justine Camus, Xiaoqing Fu, Xuanheng Hu, Oumayma Ghaneme, Lea Seibert, Marco Lebtig, Marieke A. Böcker, Anima Horlbeck, Stilianos P. Lambidis, Birgit Schittek, Dorothee Kretschmer, Michael Lämmerhofer, Andreas Peschel
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-13 (2024)
Abstract Long-chain fatty acids with antimicrobial properties are abundant on the skin and mucosal surfaces, where they are essential to restrict the proliferation of opportunistic pathogens such as Staphylococcus aureus. These antimicrobial fatty ac
Externí odkaz:
https://doaj.org/article/b8f6c51478b94aa5bdedbf00b5ad25d7
Autor:
Tobias Harm, Xiaoqing Fu, Moritz Frey, Kristina Dittrich, Adrian Brun, Tatsiana Castor, Oliver Borst, Karin Anne Lydia Müller, Tobias Geisler, Dominik Rath, Michael Lämmerhofer, Meinrad Paul Gawaz
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Coronary artery disease (CAD) often leads to adverse events resulting in significant disease burdens. Underlying risk factors often remain inapparent prior to disease incidence and the cardiovascular (CV) risk is not exclusively explained by
Externí odkaz:
https://doaj.org/article/93ab7b9776024ab59fb957d8bedb2885
Autor:
Magdalena Kremer, Sabrina Schulze, Nadja Eisenbruch, Felix Nagel, Robert Vogt, Leona Berndt, Babett Dörre, Gottfried J. Palm, Jens Hoppen, Britta Girbardt, Dirk Albrecht, Susanne Sievers, Mihaela Delcea, Ulrich Baumann, Karin Schnetz, Michael Lammers
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-25 (2024)
Abstract The Escherichia coli TetR-related transcriptional regulator RutR is involved in the coordination of pyrimidine and purine metabolism. Here we report that lysine acetylation modulates RutR function. Applying the genetic code expansion concept
Externí odkaz:
https://doaj.org/article/23d1a0b42fe14e67aa42c7c445204f48
Autor:
Lea A. Tölken, Antje D. Paulikat, Lana H. Jachmann, Alexander Reder, Manuela Gesell Salazar, Laura M. Palma Medina, Stephan Michalik, Uwe Völker, Mattias Svensson, Anna Norrby-Teglund, Katharina J. Hoff, Michael Lammers, Nikolai Siemens
Publikováno v:
Journal of Biomedical Science, Vol 31, Iss 1, Pp 1-17 (2024)
Abstract Background Streptococcus pyogenes (group A streptococcus, GAS) causes a variety of diseases ranging from mild superficial infections of the throat and skin to severe invasive infections, such as necrotizing soft tissue infections (NSTIs). Ti
Externí odkaz:
https://doaj.org/article/8cfa48c1af2241b6be605e7677b877f0
Autor:
Shu Lu, Michael Lamm
Publikováno v:
Mathematical Programming. 174:99-127
Stochastic variational inequalities (SVI) provide a unified framework for the study of a general class of nonlinear optimization and Nash-type equilibrium problems with uncertain model data. Often the true solution to an SVI cannot be found directly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::961b8930a10ace080e1e1fc73142108b
https://doi.org/10.1007/s10107-018-1279-z
https://doi.org/10.1007/s10107-018-1279-z
Autor:
Helmut Bischof, Selina Maier, Piotr Koprowski, Bogusz Kulawiak, Sandra Burgstaller, Joanna Jasińska, Kristian Serafimov, Monika Zochowska, Dominic Gross, Werner Schroth, Lucas Matt, David Arturo Juarez Lopez, Ying Zhang, Irina Bonzheim, Florian A Büttner, Falko Fend, Matthias Schwab, Andreas L Birkenfeld, Roland Malli, Michael Lämmerhofer, Piotr Bednarczyk, Adam Szewczyk, Robert Lukowski
Publikováno v:
eLife, Vol 12 (2024)
Alterations in the function of K+ channels such as the voltage- and Ca2+-activated K+ channel of large conductance (BKCa) reportedly promote breast cancer (BC) development and progression. Underlying molecular mechanisms remain, however, elusive. Her
Externí odkaz:
https://doaj.org/article/60f91b8d7664470fa1f56e117e4caef3
Autor:
Fabio Blaschke, Biswal Prabhu Prasad, Eduardo Machado Charry, Katharina Halper, Maximilian Fuchs, Roland Resel, Karin Zojer, Michael Lammer, Richard Hasso, Viktor Hacker
Publikováno v:
Catalysts, Vol 14, Iss 8, p 515 (2024)
Green hydrogen is central to the energy transition, but its production often requires expensive materials and poses environmental risks due to the perfluorinated substances used in electrolysis. This study introduces a transformative approach to gree
Externí odkaz:
https://doaj.org/article/efc1570feb54425aa3fcffd78a53b9d2