Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Michael L. Oldham"'
Autor:
Virapat Kieuvongngam, Paul Dominic B Olinares, Anthony Palillo, Michael L Oldham, Brian T Chait, Jue Chen
Publikováno v:
eLife, Vol 9 (2020)
The peptidase-containing ATP-binding cassette transporters (PCATs) are unique members of the ABC transporter family that proteolytically process and export peptides and proteins. Each PCAT contains two peptidase domains that cleave off the secretion
Externí odkaz:
https://doaj.org/article/bb16099e30c54537999cb8ffeb4bae44
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Adenosine triphosphate-binding cassette (ABC) transporters, such as multidrug resistance protein 1 (MRP1), protect against cellular toxicity by exporting xenobiotic compounds across the plasma membrane. However, constitutive MRP1 function hinders dru
Publikováno v:
eLife, Vol 5 (2016)
The transporter associated with antigen processing (TAP) is an ATP-binding cassette (ABC) transporter essential to cellular immunity against viral infection. Some persistent viruses have evolved strategies to inhibit TAP so that they may go undetecte
Externí odkaz:
https://doaj.org/article/d1c8e3dcee72400399f70b9b7c4d81fc
Autor:
Jue Chen, Anthony Palillo, Virapat Kieuvongngam, Paul Dominic B. Olinares, Brian T. Chait, Michael L. Oldham
Publikováno v:
eLife
eLife, Vol 9 (2020)
eLife, Vol 9 (2020)
The peptidase-containing ATP-binding cassette transporters (PCATs) are unique members of the ABC transporter family that proteolytically process and export peptides and proteins. Each PCAT contains two peptidase domains that cleave off the secretion
Autor:
Ermelinda Damko, Zongli Li, Michael L. Oldham, Richard K Hite, Thomas Walz, Jue Chen, Alanna M. Steffen
Publikováno v:
Nature
Cellular immunity against viral infection and tumour cells depends on antigen presentation by major histocompatibility complex class I (MHC I) molecules. Intracellular antigenic peptides are transported into the endoplasmic reticulum by the transport
Publikováno v:
eLife, Vol 5 (2016)
eLife
eLife
The transporter associated with antigen processing (TAP) is an ATP-binding cassette (ABC) transporter essential to cellular immunity against viral infection. Some persistent viruses have evolved strategies to inhibit TAP so that they may go undetecte
Publikováno v:
Proceedings of the National Academy of Sciences. 110:18132-18137
ATP-binding cassette (ABC) transporters are molecular pumps that harness the chemical energy of ATP hydrolysis to translocate solutes across the membrane. The substrates transported by different ABC transporters are diverse, ranging from small ions t
Publikováno v:
Nature
Efficient carbon utilization is critical to the survival of microorganisms in competitive environments. To optimize energy usage, bacteria have developed an integrated control system to preferentially uptake carbohydrates that support rapid growth. T