Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Michael L. Kramer"'
Publikováno v:
BioTechniques, Vol 44, Iss 3, Pp 403-411 (2008)
Parkinson's disease (PD), dementia with Lewy bodies (DLB), and multiple system atrophy are caused by α-synuclein aggregates. At present, there is no good biochemical method defining α-synuclein aggregates formed in vivo versus oligomers as a means
Externí odkaz:
https://doaj.org/article/0271ebd328c940df9ef3ad0a4e0a0c5f
Autor:
Walter Schmitz, Georg Erhardt, Matthias Gauly, Marc-Antoine Driancourt, Michael L. Kramer, Wolfgang Holtz
Publikováno v:
Livestock Science. 206:141-147
The aim of this study was to document the effectiveness of the implementation of a cosynch protocol and fixed time artificial insemination in suckled beef cows kept under range conditions in Germany. In addition, the suitability of hCG administration
Autor:
Walter J. Schulz-Schaeffer, T. Pfander, Jeffrey W. Hewett, Michael L. Kramer, Xandra O. Breakefield, John C. Hedreen, S. Siegert, Kevin Rostasy, E. Bahn
Publikováno v:
Brain Research. 1116:112-119
Familial, early onset, generalized torsion dystonia is the most common and severe primary dystonia. The majority of cases are caused by a 3-bp deletion (GAG) in the coding region of the DYT1 (TOR1A) gene. The cellular and regional distribution of tor
Publikováno v:
Journal of Neurochemistry. 87:1037-1042
The prion protein (PrP C ) has a primary role in the pathogenesis of transmissible spongiform encephalopathies. Here we analysed in detail the effect of recombinant PrP C and N- and C-terminal fragments of PrP C on the whole-cell current amplitude th
Autor:
Hans A. Kretzschmar, Susanne Liemann, Otto Windl, Alice Römer, Simone Hornemann, Hartmut Kratzin, Michael L. Kramer, Bernhard Schmidt
Publikováno v:
Journal of Biological Chemistry. 276:16711-16719
The prion protein is known to be a copper-binding protein, but affinity and stoichiometry data for the full-length protein at a physiological pH of 7 were lacking. Furthermore, it was unknown whether only the highly flexible N-terminal segment with i
Publikováno v:
Journal of the American Chemical Society. 120:5568-5574
We present results on the identification and molecular characterization of conformers with secondary cis amide peptide bonds for a number of oligopeptides containing tyrosine and phenylalanine in a...
Autor:
Gunter Fischer, Michael L. Kramer
Publikováno v:
Biopolymers. 42:49-60
Under physiological conditions, peptidyl-prolyl cis/trans isomerases catalyze powerfully the cis/trans isomerization of the -Xaa-Pro- bond (Xaa: natural amino acids) in oligopeptides and proteins (PPIases; EC 5.2.1.8). However, incorporation of proli
Autor:
Wolfgang Brück, Heike Siebert, Michael L. Kramer, Walter J. Schulz-Schaeffer, Philipp J. Kahle, Thomas Isik, Oliver M. Schlüter
Publikováno v:
Journal of Neurochemistry.
Wallerian degeneration in peripheral nerves occurs after a traumatic insult when the distal nerve part degenerates while peripheral macrophages enter the nerve stump and remove the accruing debris by phagozytosis. We used an experimental model to inv
Publikováno v:
The Journal of the Acoustical Society of America. 123(4)
Direction finding of more sources than sensors is appealing in situations with small sensor arrays. Potential applications include surveillance, teleconferencing, and auditory scene analysis for hearing aids. A new technique for time-frequency-sparse
Publikováno v:
BioTechniques. 44(3)
Parkinson's disease (PD), dementia with Lewy bodies (DLB), and multiple system atrophy are caused by alpha-synuclein aggregates. At present, there is no good biochemical method defining alpha-synuclein aggregates formed in vivo versus oligomers as a