Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Michael L. Freedman"'
Autor:
Frank Martiniuk, Elizabeth Z. Bordayo, Michael L. Freedman, Farrah D. Sajan, William H. Frey, David L. Marcus, Richard Hite
Publikováno v:
American Journal of Alzheimer's Disease & Other Dementiasr. 22:319-328
Alzheimer's disease (AD) is the major cause of dementia, accounting for 50% to 70% of the late-onset patients, with 17 to 20 million affected. It is characterized by neurofibrillary tangles, neuronal loss, and amyloid plaques in tissues of the cortex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::390b5fcad3374cc73891e8455bbcbad5
https://doi.org/10.1177/1533317507302447
https://doi.org/10.1177/1533317507302447
Autor:
Kristine M. Mosier, Mel L. Kantor, Michael L. Freedman, Alan G. Lurie, Gulnara Scaf, Gale R. Ramsby
Publikováno v:
Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology. 83:41-48
Thermoluminescent dosimeters were used to measure radiation doses at craniofacial sites in a tissue-equivalent phantom during film-based multidirectional tomography with the Tomax Ultrascan (Incubation Industries, Ivyland, Pa.) and during computed to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da6caf2f8558c74db930c10476eed617
https://doi.org/10.1016/s1079-2104(97)90089-5
https://doi.org/10.1016/s1079-2104(97)90089-5
Publikováno v:
Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology. 80:232-241
We have studied the effects of niobium beam filtration on absorbed doses, on image density and contrast, and on photon spectra with conventional and high-frequency dental x-ray generators. Added niobium reduced entry and superficial absorbed doses in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a81dd7ca18fcec15b934b12a2237cd49
https://doi.org/10.1016/s1079-2104(05)80207-0
https://doi.org/10.1016/s1079-2104(05)80207-0
Publikováno v:
International Journal of Radiation Biology. 62:555-562
The mutagenicity of open-circular DNA (containing base damage and single-strand breaks) and linear DNA (containing base damage, single-strand breaks, and one double-strand break) produced in vitro by gamma-irradiation of shuttle vector pZ189, was ana
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e0656cab09ade0d18e1a4fff81507b2
https://doi.org/10.1080/09553009214552471
https://doi.org/10.1080/09553009214552471
Publikováno v:
International Journal of Radiation Biology. 59:1115-1126
The frequencies and types of mutations induced in the target gene, supF-tRNA, of the shuttle vector pZ189 were analysed following the replication of the gamma-irradiated plasmid in the human lymphoblastoid cell line, GM606. The mutation frequency mea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2964cddc91508662f76af5be0f1e5bc1
https://doi.org/10.1080/09553009114551021
https://doi.org/10.1080/09553009114551021
Autor:
Edward I. Chang, Daniel J. Ceradini, Shang A. Loh, Shin E. Lin, Amato J. Giaccia, Nicholas Bastidas, Denise A. Chan, Eric I. Chang, Shahram Aarabi, Michael L. Freedman, Geoffrey C. Gurtner
Publikováno v:
Circulation. 116(24)
Background— Advanced age is known to impair neovascularization. Because endothelial progenitor cells (EPCs) participate in this process, we examined the effects of aging on EPC recruitment and vascular incorporation. Methods and Results— Murine n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46170928bcf0d1211ebe5297c417d134
https://pubmed.ncbi.nlm.nih.gov/18040029
https://pubmed.ncbi.nlm.nih.gov/18040029
Publikováno v:
Medical science monitor : international medical journal of experimental and clinical research. 12(1)
Manganese-dependent superoxide dismutase (MnSOD) is a major defense mechanism against potential cellular damage by reactive oxygen species (ROS). We have reported increased lipid peroxidation and decreased Cu/Zn SOD enzymatic activity in the temporal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8fd8e136c20a51e8e674650a6b13d1bd
https://pubmed.ncbi.nlm.nih.gov/16369462
https://pubmed.ncbi.nlm.nih.gov/16369462
Publikováno v:
AMA Journal of Ethics. 7
Physicians need to be aware of the cautions required with use of low molecular weight heparin and unfractionated heparin and perform a risk-benefit analysis before prescribing them to patients. Virtual Mentor is a monthly bioethics journal published
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::711039c2043d558b203efae9f1c94c5f
https://doi.org/10.1001/virtualmentor.2005.7.4.cprl1-0504
https://doi.org/10.1001/virtualmentor.2005.7.4.cprl1-0504
Autor:
Jir S. Tsai, Michael L. Freedman, Katherine Simberkoff, Charles Rodriguez, James A. Strafaci, Christopher Thomas, David L. Marcus
Publikováno v:
Experimental neurology. 150(1)
The overall peroxidation activity in brain tissue by region from patients with Alzheimer's disease (AD) and age-matched controls was determined employing the thiobarbituric acid-reactive substances (TBARS) assay, a measure of lipid peroxidation, foll
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::175fc991fe8e977f9845381e1aae7b0d
https://pubmed.ncbi.nlm.nih.gov/9514828
https://pubmed.ncbi.nlm.nih.gov/9514828
Autor:
Michael L. Freedman, David L. Marcus
Publikováno v:
Annals of the New York Academy of Sciences. 826
We studied brain glucose metabolism in patients with Alzheimer's disease and age-matched controls in vivo by PET and assessed brain glucose utilization and the phosphorylation constant K3 for hexokinase. In addition we determined in vitro the binding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49fa21dc1324123eb94ce50997111674
https://pubmed.ncbi.nlm.nih.gov/9329696
https://pubmed.ncbi.nlm.nih.gov/9329696