Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Michael L. Costello"'
Autor:
Hemant Deshmuk, Amy Bloom, Luis A. Dellamary, Simona Bot, Daniel J. Smith, Michael L. Costello, Adrian Bot, Gui-Rong Guo
Publikováno v:
Journal of Controlled Release. 95:489-500
Parenteral administration of immunoglobulins (Ig) for prevention or treatment of respiratory diseases achieves only modest concentrations of antibody in the pulmonary interstitial tissue and airways. Aerosols, including spray-dried particles, must ov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a500bf471485e90cb1089dbaf7df0636
https://doi.org/10.1016/j.jconrel.2003.12.013
https://doi.org/10.1016/j.jconrel.2003.12.013
Autor:
Michael L. Costello, Howard Gill, Dan Smith, Luis A. Dellamary, Thomas E. Tarara, Jeffry G. Weers, Anastasios Adractas, Christopher H. Woelk
Publikováno v:
Pharmaceutical Research. 17:168-174
Purpose. To assess the physical stability and aerosol characteristicsof suspensions of hollow porous microspheres (PulmoSpheres™) inHFA-134a. Methods. Cromolyn sodium, albuterol sulfate, and formoterol fumaratemicrospheres were prepared by a spray-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::970f711d4b825d7fba70f1da7d0ebdc1
https://doi.org/10.1023/a:1007513213292
https://doi.org/10.1023/a:1007513213292
Autor:
Peter Naredi, Gerrit Los, Stephen B. Howell, Michael L. Costello, Dennis P. Gately, Franz Thiebaut
Publikováno v:
Platinum and Other Metal Coordination Compounds in Cancer Chemotherapy 2 ISBN: 9781489902207
Small molecules cross membranes by either passive diffusion or are transported actively by transmembrane proteins. If given enough time, however, essentially any molecule will diffuse across a lipid bilayer down its concentration gradient. The rate a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::903cd95ec7558fb1d76efe0a4244a7ce
https://doi.org/10.1007/978-1-4899-0218-4_9
https://doi.org/10.1007/978-1-4899-0218-4_9
Autor:
John B. West, Koichi Tsukimoto, Michael L. Costello, Odile Mathieu-Costello, Ann R. Elliott, R. Prediletto, Zhenxing Fu
Publikováno v:
Journal of applied physiology (Bethesda, Md. : 1985). 73(1)
We previously showed that when pulmonary capillaries in anesthetized rabbits are exposed to a transmural pressure (Ptm) of approximately 40 mmHg, stress failure of the walls occurs with disruption of the capillary endothelium, alveolar epithelium, or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f01144b487d1bf754028710db40425d2
https://pubmed.ncbi.nlm.nih.gov/1506359
https://pubmed.ncbi.nlm.nih.gov/1506359
Publikováno v:
Muscle & Nerve. 2:299-303
Edema and increased endoneurial fluid pressure developed in peripheral nerves of rats that received a diet containing 40% galactose during a study of the role of sugar alcohols in producing neuropathy. Fluid pressure was elevated starting in the thir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aef7a0d2a10276160e3350a3a5f32e5a
https://doi.org/10.1002/mus.880020410
https://doi.org/10.1002/mus.880020410
Publikováno v:
Annals of Neurology. 8:392-401
The dynamics of endoneurial edema were studied by quantifying endoneurial fluid pressure (EFP) during the development of lead neuropathy and correlating these data with changes in blood-nerve barrier permeability and with morphological alterations in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a411e849c8352748a5401b6ba85cbc6a
https://doi.org/10.1002/ana.410080410
https://doi.org/10.1002/ana.410080410
Publikováno v:
Clinical biochemistry. 15(3)
Increased Hemoglobin A 1 (HbA 1 ) occurs in diabetes mellitus as a direct consequence of hyperglycemia, which causes postsynthetic modification of hemoglobin proportional to blood glucose concentration. Glycosylation of hemoglobin is demonstrable als
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02a59eb01c13712bf976b1c06a0e81ee
https://pubmed.ncbi.nlm.nih.gov/7116620
https://pubmed.ncbi.nlm.nih.gov/7116620
Publikováno v:
Journal of neuropathology and experimental neurology. 40(6)
The sorbitol pathway has been suggested as a biochemical mechanism for peripheral neuropathy in diabetes, due to accumulation of osmotically active polyols which cause endoneurial edema. The purpose of this study was to compare endoneurial fluid pres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67ac35f6878a25d035a9baab2d4e5858
https://pubmed.ncbi.nlm.nih.gov/7299419
https://pubmed.ncbi.nlm.nih.gov/7299419
Publikováno v:
Musclenerve. 5(4)
A technique for microgravimetric analysis of nerve edema was used to demonstrate increased water content in hexachlorophene neuropathy. The method was modified from one used previously to quantify brain edema by using density gradient columns prepare
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::caa7d98c476c3a07864500275b581d4d
https://pubmed.ncbi.nlm.nih.gov/6285188
https://pubmed.ncbi.nlm.nih.gov/6285188
Autor:
Henry C. Powell, Michael L. Costello, Peter W. Lampert, Benjamin W. Zweifach, Robert R. Myers
Publikováno v:
Brain research. 148(2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d146e22bcecef99ef6cc9e0a4eb39ae
https://pubmed.ncbi.nlm.nih.gov/656947
https://pubmed.ncbi.nlm.nih.gov/656947