HDAC5 Expression in Urothelial Carcinoma Cell Lines Inhibits Long-Term Proliferation but Can Promote Epithelial-to-Mesenchymal Transition

Autor: Patrick Petzsch, Karl Köhrer, Ananda Ayyappan Jaguva Vasudevan, Kai Stühler, Wolfgang A. Schulz, Michèle J. Hoffmann, Michael L. C. Beck, Gereon Poschmann, Constanze Wiek, Günter Niegisch

Publikováno v: International Journal of Molecular Sciences, Vol 20, Iss 9, p 2135 (2019)
International Journal of Molecular Sciences
Volume 20
Issue 9

Class I histone deacetylases (HDACs) generally promote cell proliferation and tumorigenesis, whereas class IIA HDACs like HDAC4 and HDAC5 may promote or impede cancer development in a tissue-dependent manner. In urothelial carcinoma (UC), HDAC5 is of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44fd3c622d5cb32db79129bca85c0a08
https://www.mdpi.com/1422-0067/20/9/2135