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pro vyhledávání: '"Michael L. Bowe"'
Autor:
Cicely L. Schramm, Michael L. Bowe, Laura A. Skerlos, Grigory S. Filonov, Yong X. Chen, Daniel M. Appledorn
Publikováno v:
Cancer Research. 79:5266-5266
Differential metabolic requirements of tumor cells have gained recognition as attractive therapeutic targets. For example, clinical trials are currently underway to test the efficacy of the glutaminase-1 (GLS1) inhibitor CB-839 in a variety of indica
Autor:
Dyke P. McEwen, Cicely L. Schramm, Michael L. Bowe, Daniel M. Appledorn, Yong X. Chen, Grigory S. Filonov, Laura A. Skerlos
Publikováno v:
Cancer Research. 78:374-374
Metabolic reprogramming is a hallmark of tumor cells, owing to the increased energetic and biosynthetic demands associated with maintaining high rates of proliferation. Therapeutic strategies targeting unique, critical metabolic pathways of tumor cel