Zobrazeno 1 - 10
of 353
pro vyhledávání: '"Michael L. Shuler"'
Autor:
Victoria L. Slaughter, John W. Rumsey, Rachel Boone, Duaa Malik, Yunqing Cai, Narasimhan Narasimhan Sriram, Christopher J. Long, Christopher W. McAleer, Stephen Lambert, Michael L. Shuler, J. J. Hickman
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease and strongly correlates with the growing incidence of obesity and type II diabetes. We have developed a human-on-a-chip model composed of human hepatocytes and adipose
Externí odkaz:
https://doaj.org/article/3547c91f62364f5898fce5860fb718e0
Autor:
Virginia M. Smith, Huan Nguyen, John W. Rumsey, Christopher J. Long, Michael L. Shuler, James J. Hickman
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Myasthenia gravis (MG) is a chronic and progressive neuromuscular disease where autoantibodies target essential proteins such as the nicotinic acetylcholine receptor (nAChR) at the neuromuscular junction (NMJ) causing muscle fatigue and weakness. Aut
Externí odkaz:
https://doaj.org/article/f5929ad188e345ea8c3b30d46c3e09f4
Autor:
Samaneh Kamali Sarvestani, Reece K. DeHaan, Paula G. Miller, Shree Bose, Xiling Shen, Michael L. Shuler, Emina H. Huang
Publikováno v:
iScience, Vol 23, Iss 11, Pp 101719- (2020)
Summary: Colon cancer remains the third most common cause of cancer in the US, and the third most common cause of cancer death. Worldwide, colon cancer is the second most common cause of cancer and cancer deaths. At least 25% of patients still presen
Externí odkaz:
https://doaj.org/article/b4b49b55721f43a8bb15dc8c0ab23e6c
Autor:
Trevor Sasserath, John W. Rumsey, Christopher W. McAleer, Lee Richard Bridges, Christopher J. Long, Daniel Elbrecht, Franz Schuler, Adrian Roth, Christina Bertinetti‐LaPatki, Michael L. Shuler, James J. Hickman
Publikováno v:
Advanced Science, Vol 7, Iss 13, Pp n/a-n/a (2020)
Abstract A functional, human, multiorgan, pumpless, immune system‐on‐a‐chip featuring recirculating THP‐1 immune cells with cardiomyocytes, skeletal muscle, and liver in separate compartments in a serum‐free medium is developed. This in vit
Externí odkaz:
https://doaj.org/article/e002bbb5aaeb472b9e127685dc612392
Autor:
Magnolia Ariza-Nieto, Joshua B Alley, Sanjay Samy, Laura Fitzgerald, Francoise Vermeylen, Michael L Shuler, José O Alemán
Publikováno v:
Endocrine Connections, Vol 7, Iss 9, Pp 975-982 (2018)
Objective: We sought to discover secreted biomarkers to monitor the recovery of physiological adiponectin levels with metabolic surgery, focusing on epigenetic changes that might predict adiponectin function. Design: We conducted a prospective obser
Externí odkaz:
https://doaj.org/article/d9c5710576374060aa385091d5c05e9e
Publikováno v:
APL Bioengineering, Vol 3, Iss 2, Pp 021501-021501-12 (2019)
Recent advances in organ-on-a-chip technology have resulted in numerous examples of microscale systems that faithfully mimic the physiology and pathology of human organs and diseases. The next step in this field, which has already been partially demo
Externí odkaz:
https://doaj.org/article/6db4be3562444c9b9d4d4ea3182bc63f
Publikováno v:
EBioMedicine, Vol 5, Iss C, Pp 30-39 (2016)
Organ-on-a-chip devices have gained attention in the field of in vitro modeling due to their superior ability in recapitulating tissue environments compared to traditional multiwell methods. These constructed growth environments support tissue differ
Externí odkaz:
https://doaj.org/article/22f36067bbea4e5bb3fa9d8e5ae627f0
Autor:
Yunqing Cai, Michael L. Shuler, Narasimhan Narasimhan Sriram, Christopher J. Long, Duaa Malik, Victoria L. Slaughter, Rachel Boone, Christopher W. McAleer, Stephen Lambert, John W. Rumsey, James J. Hickman
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Scientific Reports
Scientific Reports
Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease and strongly correlates with the growing incidence of obesity and type II diabetes. We have developed a human-on-a-chip model composed of human hepatocytes and adipose tissue c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b48e79795bf3b3db7d946cf3ceefe2e9
https://doaj.org/article/3547c91f62364f5898fce5860fb718e0
https://doaj.org/article/3547c91f62364f5898fce5860fb718e0
Autor:
Chak Ming Leung, Pim de Haan, Kacey Ronaldson-Bouchard, Ge-Ah Kim, Jihoon Ko, Hoon Suk Rho, Zhu Chen, Pamela Habibovic, Noo Li Jeon, Shuichi Takayama, Michael L. Shuler, Gordana Vunjak-Novakovic, Olivier Frey, Elisabeth Verpoorte, Yi-Chin Toh
Publikováno v:
Nature Reviews. Methods Primers, 2(1):33. Nature Publishing Group
Nature Reviews Methods Primers, 2(1):33
Nature Reviews Methods Primers, 2(1):33
Organs-on-chips (OoCs) are systems containing engineered or natural miniature tissues grown inside microfluidic chips. To better mimic human physiology, the chips are designed to control cell microenvironments and maintain tissue-specific functions.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db296ec6b13140d1f09f1eb59876cbb4
https://doi.org/10.1038/s43586-022-00118-6
https://doi.org/10.1038/s43586-022-00118-6
Publikováno v:
TAXOL® ISBN: 9780138737368
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4b2da5b0b1b7c22dff0f6cf295dfa2b
https://doi.org/10.1201/9780138737361-6
https://doi.org/10.1201/9780138737361-6
