Zobrazeno 1 - 10
of 353
pro vyhledávání: '"Michael L Shuler"'
Autor:
Magnolia Ariza-Nieto, Joshua B Alley, Sanjay Samy, Laura Fitzgerald, Francoise Vermeylen, Michael L Shuler, José O Alemán
Publikováno v:
Endocrine Connections, Vol 7, Iss 9, Pp 975-982 (2018)
Objective: We sought to discover secreted biomarkers to monitor the recovery of physiological adiponectin levels with metabolic surgery, focusing on epigenetic changes that might predict adiponectin function. Design: We conducted a prospective obser
Externí odkaz:
https://doaj.org/article/d9c5710576374060aa385091d5c05e9e
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0123717 (2015)
Mammary tumors and malignant breast cancer cell lines over-express the coagulation factor, tissue factor (TF). High expression of TF is associated with a poor prognosis in breast cancer. Tissue factor pathway inhibitor (TFPI), the endogenous inhibito
Externí odkaz:
https://doaj.org/article/2847a359ef014c7d81b0c832a92d64cd
Autor:
Yunqing Cai, Michael L. Shuler, Narasimhan Narasimhan Sriram, Christopher J. Long, Duaa Malik, Victoria L. Slaughter, Rachel Boone, Christopher W. McAleer, Stephen Lambert, John W. Rumsey, James J. Hickman
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Scientific Reports
Scientific Reports
Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease and strongly correlates with the growing incidence of obesity and type II diabetes. We have developed a human-on-a-chip model composed of human hepatocytes and adipose tissue c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b48e79795bf3b3db7d946cf3ceefe2e9
https://doaj.org/article/3547c91f62364f5898fce5860fb718e0
https://doaj.org/article/3547c91f62364f5898fce5860fb718e0
Autor:
Chak Ming Leung, Pim de Haan, Kacey Ronaldson-Bouchard, Ge-Ah Kim, Jihoon Ko, Hoon Suk Rho, Zhu Chen, Pamela Habibovic, Noo Li Jeon, Shuichi Takayama, Michael L. Shuler, Gordana Vunjak-Novakovic, Olivier Frey, Elisabeth Verpoorte, Yi-Chin Toh
Publikováno v:
Nature Reviews. Methods Primers, 2(1):33. Nature Publishing Group
Nature Reviews Methods Primers, 2(1):33
Nature Reviews Methods Primers, 2(1):33
Organs-on-chips (OoCs) are systems containing engineered or natural miniature tissues grown inside microfluidic chips. To better mimic human physiology, the chips are designed to control cell microenvironments and maintain tissue-specific functions.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db296ec6b13140d1f09f1eb59876cbb4
https://doi.org/10.1038/s43586-022-00118-6
https://doi.org/10.1038/s43586-022-00118-6
Publikováno v:
TAXOL® ISBN: 9780138737368
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4b2da5b0b1b7c22dff0f6cf295dfa2b
https://doi.org/10.1201/9780138737361-6
https://doi.org/10.1201/9780138737361-6
Autor:
Virginia M. Smith, Huan Nguyen, John W. Rumsey, Christopher J. Long, Michael L. Shuler, James J. Hickman
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Frontiers in Cell and Developmental Biology
Frontiers in Cell and Developmental Biology
Myasthenia gravis (MG) is a chronic and progressive neuromuscular disease where autoantibodies target essential proteins such as the nicotinic acetylcholine receptor (nAChR) at the neuromuscular junction (NMJ) causing muscle fatigue and weakness. Aut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57e991ad92a346af3a2eedc6fb04770f
https://www.frontiersin.org/articles/10.3389/fcell.2021.745897/full
https://www.frontiersin.org/articles/10.3389/fcell.2021.745897/full
Publikováno v:
BioChip Journal. 13:115-126
Microphysiological systems (MPS), also known as organ-on-a-chip technology, combine cell culture models and microtechnology to mimic tissue microenvironment and provide improved physiological relevance of in vitro model systems. The unique advantage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4eac53f96c46af8054d72401056537c
https://doi.org/10.1007/s13206-019-3201-z
https://doi.org/10.1007/s13206-019-3201-z
Autor:
Michael L. Shuler, Shree Bose, Emina H. Huang, Xiling Shen, Paula G. Miller, Reece K. DeHaan, Samaneh K. Sarvestani
Publikováno v:
iScience, Vol 23, Iss 11, Pp 101719-(2020)
iScience
iScience
Summary Colon cancer remains the third most common cause of cancer in the US, and the third most common cause of cancer death. Worldwide, colon cancer is the second most common cause of cancer and cancer deaths. At least 25% of patients still present
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bab758dc014de3372b1bd9d3886f5c1
http://www.sciencedirect.com/science/article/pii/S2589004220309160
http://www.sciencedirect.com/science/article/pii/S2589004220309160
Publikováno v:
Biotechnology progressREFERENCES. 37(2)
Drug development is often hindered by the failure of preclinical models to accurately assess and predict the efficacy and safety of drug candidates. Body-on-a-chip (BOC) microfluidic devices, a subset of microphysiological systems (MPS), are being cr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a043979ecd2768a7a04a478e7fc60a3
https://pubmed.ncbi.nlm.nih.gov/33274840
https://pubmed.ncbi.nlm.nih.gov/33274840