Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Michael L, Meyers"'
Autor:
Carrie L. Kitko, Mukta Arora, Zachariah DeFilipp, Mohammad Abu Zaid, Antonio Di Stasi, Vedran Radojcic, Courtney B. Betts, Lisa M. Coussens, Michael L. Meyers, Hope Qamoos, Peter Ordentlich, Vinit Kumar, Christine Quaranto, Aaron Schmitt, Yu Gu, Bruce R. Blazar, Trent P. Wang, Amandeep Salhotra, Iskra Pusic, Madan Jagasia, Stephanie J. Lee
Publikováno v:
Journal of Clinical Oncology. 41:1864-1875
PURPOSE Chronic graft-versus-host disease (cGVHD) remains the major cause of late morbidity after allogeneic hematopoietic cell transplantation. Colony-stimulating factor 1 receptor (CSF-1R)–dependent macrophages promote cGVHD fibrosis, and their e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3419a8fcbd3a193b917867f44b5f1248
https://doi.org/10.1200/jco.22.00958
https://doi.org/10.1200/jco.22.00958
Autor:
Ghayas C. Issa, Ibrahim Aldoss, John DiPersio, Branko Cuglievan, Richard Stone, Martha Arellano, Michael J. Thirman, Manish R. Patel, David S. Dickens, Shalini Shenoy, Neerav Shukla, Hagop Kantarjian, Scott A. Armstrong, Florian Perner, Jennifer A. Perry, Galit Rosen, Rebecca G. Bagley, Michael L. Meyers, Peter Ordentlich, Yu Gu, Vinit Kumar, Steven Smith, Gerard M. McGeehan, Eytan M. Stein
Publikováno v:
Nature. 615:920-924
Targeting critical epigenetic regulators reverses aberrant transcription in cancer, thereby restoring normal tissue function1–3. The interaction of menin with lysine methyltransferase 2A (KMT2A), an epigenetic regulator, is a dependence in acute le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb9ceb0202f73dbb3b711cc570b8af1a
https://doi.org/10.1038/s41586-023-05812-3
https://doi.org/10.1038/s41586-023-05812-3
Autor:
Ghayas C. Issa, Ibrahim Aldoss, John F. DiPersio, Branko Cuglievan, Richard M. Stone, Martha L. Arellano, Michael J. Thirman, Manish R. Patel, David Dickens, Shalini Shenoy, Neerav Shukla, Galit Rosen, Rebecca G. Bagley, Michael L. Meyers, Kate Madigan, Peter Ordentlich, Yu Gu, Steven Smith, Gerard M. McGeehan, Eytan Stein
Publikováno v:
Blood. 140:150-152
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::885a2d3d98a82924ef3913b11c4926a4
https://doi.org/10.1182/blood-2022-164849
https://doi.org/10.1182/blood-2022-164849
Autor:
Ghayas C. Issa, Branko Cuglievan, Eytan Stein, Martha L. Arellano, Andrius Žucenka, Nandita Khera, Richard M. Stone, Michael J. Thirman, John F. DiPersio, Nicole Karras, Yu Gu, Rebecca G. Bagley, Galit Rosen, David Tamang, Kimberly Dishman, Sushama Scalera, Michael L. Meyers, Kate Madigan, Nicole McNeer, Ibrahim Aldoss
Publikováno v:
Blood. 140:914-916
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c8de19932f8a29ddba13169e64695a07
https://doi.org/10.1182/blood-2022-164600
https://doi.org/10.1182/blood-2022-164600
Autor:
Joe McDonough, G. Lesa, Franca Ligas, Miguel Rivera, Ira Jacobs, Andrew D.J. Pearson, Malcolm A. Smith, Maureen Hattersley, Dominik Karres, Aundrietta D. Duncan, Nada Jabado, Daniel D. De Carvalho, Koen Norga, Peter C. Adamson, Donna Ludwinski, Gregory H. Reaman, Brian Gadbaw, Elizabeth Fox, Samuel C. Blackman, Mark W. Kieran, Gilles Vassal, Christian Baumann, Vickie Buenger, Delphine Heenen, Scott A. Armstrong, Michael J. Kelly, Amy Barone, Adrian Senderowicz, Franck Bourdeaut, Martha Donoghue, Tilmann Taube, Peter T.C. Ho, Lynley V. Marshall, Patrick A. Brown, Michael L. Meyers, Kimberly Stegmaier, Zariana Nikolova, Susan L. Weiner
Publikováno v:
European Journal of Cancer. 139:135-148
The fifth multistakeholder Paediatric Strategy Forum focussed on epigenetic modifier therapies for children and adolescents with cancer. As most mutations in paediatric malignancies influence chromatin-associated proteins or transcription and paediat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c517dea500b05206723e5227a0df2155
https://doi.org/10.1016/j.ejca.2020.08.014
https://doi.org/10.1016/j.ejca.2020.08.014
Autor:
Fang Wang, Jane B. Trepel, Serap Sankoh, Peter Ordentlich, Lei Wang, Emmett V. Schmidt, Mateusz Opyrchal, Suresh S. Ramalingam, Min-Jung Lee, Pasi A. Jänne, Dmitry I. Gabrilovich, Elaine Shum, David Tamang, Navid Hafez, Sunmin Lee, Matthew D. Hellmann, Akira Yuno, Susan Brouwer, Michael L. Meyers, Luis E. Raez
Publikováno v:
Clin Cancer Res
Purpose: New therapies are needed to treat immune checkpoint inhibitor–resistant non–small cell lung cancer (NSCLC) and identify biomarkers to personalize treatment. Epigenetic therapies, including histone deacetylase inhibitors, may synergize wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04596a3f0e4f92bfa08108aa9a9ca260
https://pubmed.ncbi.nlm.nih.gov/33203644
https://pubmed.ncbi.nlm.nih.gov/33203644
Autor:
Andrew Dj, Pearson, Kimberly, Stegmaier, Franck, Bourdeaut, Gregory, Reaman, Delphine, Heenen, Michael L, Meyers, Scott A, Armstrong, Patrick, Brown, Daniel, De Carvalho, Nada, Jabado, Lynley, Marshall, Miguel, Rivera, Malcolm, Smith, Peter C, Adamson, Amy, Barone, Christian, Baumann, Samuel, Blackman, Vickie, Buenger, Martha, Donoghue, Aundrietta D, Duncan, Elizabeth, Fox, Brian, Gadbaw, Maureen, Hattersley, Peter, Ho, Ira, Jacobs, Michael J, Kelly, Mark, Kieran, Giovanni, Lesa, Franca, Ligas, Donna, Ludwinski, Joe, McDonough, Zariana, Nikolova, Koen, Norga, Adrian, Senderowicz, Tilmann, Taube, Susan, Weiner, Dominik, Karres, Gilles, Vassal
Publikováno v:
European journal of cancer
The fifth multistakeholder Paediatric Strategy Forum focussed on epigenetic modifier therapies for children and adolescents with cancer. As most mutations in paediatric malignancies influence chromatin-associated proteins or transcription and paediat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::eee50db77fe7c0e7c72791d7c8fbba20
https://repository.uantwerpen.be/docstore/d:irua:3630
https://repository.uantwerpen.be/docstore/d:irua:3630
Autor:
Stephanie J. Lee, Zachariah DeFilipp, Hope Qamoos, Peter Ordentlich, Aaron Schmitt, Mohammad Abu Zaid, Amandeep Salhotra, Mukta Arora, Carrie L. Kitko, Christine Quaranto, Michael L. Meyers, Antonio Di Stasi, Yu Gu, Iskra Pusic, Vedran Radojcic
Publikováno v:
Blood. 138:263-263
Background: Axatilimab (Axa) is an IgG4 humanized monoclonal antibody with high affinity binding to CSF-1R. Axa blocks CSF1 and IL-34 binding and activation of CSF-1R signaling, a key pathway involved in the expansion and infiltration of donor-derive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a59e1ef0e09bc9385bbea6ae290832e6
https://doi.org/10.1182/blood-2021-146050
https://doi.org/10.1182/blood-2021-146050
Autor:
Manish R. Patel, Martha Arellano, Yifan Huang, Rebecca G. Bagley, Michael L. Meyers, Michael J. Thirman, Ghayas C. Issa, Ibrahim Aldoss, Galit Rosen, Richard Stone, John F. DiPersio, Steve Smith, Eytan M. Stein
Publikováno v:
Blood. 138:699-699
Introduction: Translocations involving the MLL gene on chromosome 11q23 result in fusions with ≥10 partner genes that act as drivers in relatively chemotherapy resistant MLL-rearranged (MLLr) leukemias. These chimeric proteins form part of protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::000dc27a081dc9ef983ee4af239326c3
https://doi.org/10.1182/blood-2021-146944
https://doi.org/10.1182/blood-2021-146944
Autor:
Michael L. Meyers, Stephanie J. Lee, Christine Quaranto, Mukta Arora, Madan Jagasia, Antonio Di Stasi, Bruce R. Blazar, Peter Ordentlich, Serap Sankoh, Aaron Schmitt, Geoff R. Hill, Daniel J. Weisdorf, Mohammad Abu Zaid
Publikováno v:
Blood. 136:1-2
Background: Chronic graft versus host disease (cGVHD) is a major cause of morbidity and late non-relapse mortality after allogeneic hematopoietic cell transplantation and is commonly associated with prolonged immune suppression. Patients (pts) with i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d377c36b82c2ec61b609db88cd7996dc
https://doi.org/10.1182/blood-2020-141553
https://doi.org/10.1182/blood-2020-141553