Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Michael Kriegler"'
Autor:
Carl F. Perez, Takashi Tsuruo, Kyunghee Choi, Igor B. Roninson, Michael Kriegler, Randi Kaplan Stern, Thomas O. Frommel
Publikováno v:
Proceedings of the National Academy of Sciences. 88:7386-7390
Multidrug resistance (MDR) in mammalian cells is associated with the expression of the MDR1 gene encoding P-glycoprotein (P-gp), an and active efflux pump for various lipophilic compounds. MDR transfectants can be isolated after MDR1 gene transfer an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f2ff434a5f89a5fa1bbf99cb0d2e6bf
https://doi.org/10.1073/pnas.88.16.7386
https://doi.org/10.1073/pnas.88.16.7386
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 90(3)
The selectins are adhesion receptors that play key roles in leukocyte trafficking. Each has an N-terminal C-type lectin domain that binds to specific carbohydrates in a calcium-dependent manner. L-selectin recognizes sulfated, sialylated ligands on l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::056fe35d4e99ce1c8ce12a14280adc3e
https://pubmed.ncbi.nlm.nih.gov/7679216
https://pubmed.ncbi.nlm.nih.gov/7679216
Publikováno v:
Cell. 63(2)
In addition to the induction of tumor regression, tumor necrosis factor (TNF) has been implicated as the causative agent in a number of pathologies, including cachexia, septic shock, rheumatoid arthritis, autoimmunity, and induction of HIV expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6deafacf323c9683e7862a4c26ce001
https://pubmed.ncbi.nlm.nih.gov/2208285
https://pubmed.ncbi.nlm.nih.gov/2208285
Autor:
Michael Kriegler
Publikováno v:
Gene Transfer and Expression ISBN: 9781349118939
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b24e2ac5e9514383e117ae8c825c43de
https://doi.org/10.1007/978-1-349-11891-5_7
https://doi.org/10.1007/978-1-349-11891-5_7
Autor:
Michael Kriegler
Publikováno v:
Gene Transfer and Expression ISBN: 9781349118939
Background information on the engineering of retroviral vectors and retrovirus packaging lines can be found in Part I in the chapter on retroviral vectors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::06c9ee5a293a70d97b383b6a379d4215
https://doi.org/10.1007/978-1-349-11891-5_9
https://doi.org/10.1007/978-1-349-11891-5_9
Autor:
Michael Kriegler
Publikováno v:
Gene Transfer and Expression ISBN: 9781349118939
Once you have assembled your expression construct or recombinant virus and have either transfected or infected the appropriate cells, you will want to study the gene product of interest. If that gene product is a protein molecule, you have a substant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a6ffd9329d81ca0d55620280df9be75b
https://doi.org/10.1007/978-1-349-11891-5_3
https://doi.org/10.1007/978-1-349-11891-5_3
Autor:
Michael Kriegler
Publikováno v:
Gene Transfer and Expression ISBN: 9781349118939
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae69950236aaab852de872960877efa1
https://doi.org/10.1007/978-1-349-11891-5_8
https://doi.org/10.1007/978-1-349-11891-5_8
Autor:
Michael Kriegler
Publikováno v:
Gene Transfer and Expression ISBN: 9781349118939
There are, of course, several methods that may be employed to monitor and quantitate successful gene transfer. One can assay for the presence of transferred DNA by a Southern blot of genomic DNA or, if the transferred DNA has some unique sequence fea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff4f79ae3c4e08289d9418afde70da39
https://doi.org/10.1007/978-1-349-11891-5_11
https://doi.org/10.1007/978-1-349-11891-5_11
Autor:
Michael Kriegler
Publikováno v:
Gene Transfer and Expression ISBN: 9781349118939
Methods for gene transfer vary widely in their relative efficiencies. At an appropriate multiplicity of infection, virtually all the cells in a population can be infected with a recombinant retrovirus. All other means of stable transformation are les
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e31dbf975201d631b68dce85e0ac7780
https://doi.org/10.1007/978-1-349-11891-5_6
https://doi.org/10.1007/978-1-349-11891-5_6