Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Michael Kopf"'
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-14 (2024)
Abstract Background Tubulointerstitial kidney disease associated microenvironmental dysregulation, like acidification, inflammation and fibrosis, affects tubule cells and fibroblasts. Micromilieu homeostasis influences intracellular signaling and int
Externí odkaz:
https://doaj.org/article/4cb8fe8b1a674039a9beef8f7bf9123b
Autor:
Virginie Dubourg, Gerald Schwerdt, Barbara Schreier, Michael Kopf, Sigrid Mildenberger, Ralf A. Benndorf, Michael Gekle
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Endothelial cells (EC) are key players in vascular function, homeostasis and inflammation. EC show substantial heterogeneity due to inter-individual variability (e.g. sex-differences) and intra-individual differences as they originate from d
Externí odkaz:
https://doaj.org/article/d85fe54df585415eadc3aa04dfbb82dd
Autor:
Virginie Dubourg, Marie-Christin Schulz, Philipp Terpe, Stefanie Ruhs, Michael Kopf, Michael Gekle
Publikováno v:
PLoS ONE, Vol 18, Iss 8, p e0290373 (2023)
Extracellular pH is an important parameter influencing cell function and fate. Microenvironmental acidosis accompanies different pathological situations, including inflammation, hypoxia and ischemia. Research focussed mainly on acidification of the t
Externí odkaz:
https://doaj.org/article/360195c8a1d14d38b2775731fb86792c
Autor:
Katharina Stroedecke, Sandra Meinel, Fritz Markwardt, Udo Kloeckner, Nicole Straetz, Katja Quarch, Barbara Schreier, Michael Kopf, Michael Gekle, Claudia Grossmann
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Abstract The EGF receptor (EGFR) has been extensively studied in tumor biology and recently a role in cardiovascular pathophysiology was suggested. The mineralocorticoid receptor (MR) is an important effector of the renin–angiotensin–aldosterone-
Externí odkaz:
https://doaj.org/article/e7c08a9ce14145d4984ef05ebc288861
Autor:
Marie-Christin Schulz, Virginie Dubourg, Alexander Nolze, Michael Kopf, Gerald Schwerdt, Michael Gekle
Publikováno v:
Antioxidants, Vol 12, Iss 2, p 412 (2023)
Crosstalk of renal epithelial cells with interstitial fibroblasts plays an important role in kidney pathophysiology. A previous study showed that crosstalk between renal epithelial cells and renal fibroblasts protects against acidosis-induced damage.
Externí odkaz:
https://doaj.org/article/4404032215334d618415a9bd78a7e602
Publikováno v:
Toxins, Vol 13, Iss 3, p 219 (2021)
The kidney is threatened by a lot of potentially toxic substances. To study the influence of the nephrotoxin ochratoxin A (OTA) we established a cell co-culture model consisting of human renal proximal tubule cells and fibroblasts. We studied the eff
Externí odkaz:
https://doaj.org/article/56eda8642bdb419182551f8956b797d9
Publikováno v:
Cells, Vol 9, Iss 1, p 143 (2020)
Environmental food contaminants constitute a threat to human health. For instance, the globally spread mycotoxin Ochratoxin A (OTA) contributes to chronic kidney damage by affecting proximal tubule cells via unknown mechanisms. We applied a top-down
Externí odkaz:
https://doaj.org/article/4991c4cf9558471887dc33b64ed6d3d0
Autor:
Shohreh Shahabi, Shiquan He, Michael Kopf, Marisa Mariani, Joann Petrini, Giovanni Scambia, Cristiano Ferlini
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e61955 (2013)
Cancer incidence and mortality are higher in males than in females, suggesting that some gender-related factors are behind such a difference. To analyze this phenomenon the most recent Surveillance, Epidemiology and End Results (SEER) database served
Externí odkaz:
https://doaj.org/article/1ae989d8fc8a4600bd3590594a5e72e6
Publikováno v:
Toxins
Volume 13
Issue 3
Toxins, Vol 13, Iss 219, p 219 (2021)
Volume 13
Issue 3
Toxins, Vol 13, Iss 219, p 219 (2021)
The kidney is threatened by a lot of potentially toxic substances. To study the influence of the nephrotoxin ochratoxin A (OTA) we established a cell co-culture model consisting of human renal proximal tubule cells and fibroblasts. We studied the eff
Autor:
Michael Kopf, Christophe Rico
Publikováno v:
Communicative Approaches for Ancient Languages
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a93601e9b424160ea38f24a06fed09f4
https://doi.org/10.5040/9781350157378.ch-014
https://doi.org/10.5040/9781350157378.ch-014