Zobrazeno 1 - 10
of 138
pro vyhledávání: '"Michael Kolbe"'
Autor:
Sukrit Srivastava, Michael Kolbe
Publikováno v:
ACS Omega, Vol 8, Iss 35, Pp 31698-31713 (2023)
Externí odkaz:
https://doaj.org/article/96e933e8b66f463782aafb7396729e1c
Autor:
Sukrit Srivastava, Sonia Verma, Mohit Kamthania, Ajay Kumar Saxena, Kailash C Pandey, Veena Pande, Michael Kolbe
Publikováno v:
PLoS ONE, Vol 18, Iss 3, p e0282580 (2023)
Nipah virus (NiV) is an emerging zoonotic virus that caused several serious outbreaks in the south asian region with high mortality rates ranging from 40 to 90% since 2001. NiV infection causes lethal encephalitis and respiratory disease with the sym
Externí odkaz:
https://doaj.org/article/bf14cb7283b84d189cdd700b7fb3ec17
Autor:
Julia A. Horstmann, Michele Lunelli, Hélène Cazzola, Johannes Heidemann, Caroline Kühne, Pascal Steffen, Sandra Szefs, Claire Rossi, Ravi K. Lokareddy, Chu Wang, Laurine Lemaire, Kelly T. Hughes, Charlotte Uetrecht, Hartmut Schlüter, Guntram A. Grassl, Theresia E. B. Stradal, Yannick Rossez, Michael Kolbe, Marc Erhardt
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Flagellin proteins of Salmonella flagella are methylated. Here, the authors show that flagellin methylation facilitates adhesion of Salmonella to hydrophobic host-cell surfaces, and contributes to efficient gut colonization and host infection.
Externí odkaz:
https://doaj.org/article/a2e29bfad3e243b1b5b15ef5ca3af75a
Autor:
Chu Wang, Christian Nehls, Dirk Baabe, Olaf Burghaus, Robert Hurwitz, Thomas Gutsmann, Martin Bröring, Michael Kolbe
Publikováno v:
PLoS Pathogens, Vol 17, Iss 11 (2021)
The methyltransferase FliB posttranslationally modifies surface-exposed ɛ-N-lysine residues of flagellin, the protomer of the flagellar filament in Salmonella enterica (S. enterica). Flagellin methylation, reported originally in 1959, was recently s
Externí odkaz:
https://doaj.org/article/26208fccf0c6414481c713bbf711acd0
Publikováno v:
Biochemistry and Biophysics Reports, Vol 27, Iss , Pp 101039- (2021)
Gram-negative pathogens evolved a syringe-like nanomachine, termed type 3 secretion system, to deliver protein effectors into the cytoplasm of host cells. An essential component of this system is a long helical needle filament that protrudes from the
Externí odkaz:
https://doaj.org/article/a8f59de1bfad421ea6a2c5db03cc3681
Autor:
Michele Lunelli, Antje Kamprad, Jörg Bürger, Thorsten Mielke, Christian M T Spahn, Michael Kolbe
Publikováno v:
PLoS Pathogens, Vol 16, Iss 2, p e1008263 (2020)
The Type III Secretion Systems (T3SS) needle complex is a conserved syringe-shaped protein translocation nanomachine with a mass of about 3.5 MDa essential for the survival and virulence of many Gram-negative bacterial pathogens. This system is compo
Externí odkaz:
https://doaj.org/article/d608e86b1e894752a489471a22f14a8f
Publikováno v:
Biosensors, Vol 11, Iss 3, p 60 (2021)
The aryl hydrocarbon receptor (AhR) is a highly conserved cellular sensor of a variety of environmental pollutants and dietary-, cell- and microbiota-derived metabolites with important roles in fundamental biological processes. Deregulation of the Ah
Externí odkaz:
https://doaj.org/article/0b37e14ab533421aaaac490023a8cf4e
Autor:
Jonathan Reinhardt, Michael Kolbe
Publikováno v:
Bio-Protocol, Vol 4, Iss 22 (2014)
Shigella flexneri (S. flexneri) is a Gram-negative bacterium that causes gastroenteritis and shigellosis in humans. In order to establish and maintain an infection, S. flexneri utilises a type three secretion system (T3SS) to deliver virulence factor
Externí odkaz:
https://doaj.org/article/a7441b737e2a45b7a65b5c3ab25aa8ee
Publikováno v:
PLoS Pathogens, Vol 10, Iss 1, p e1003881 (2014)
The Type III Secretion System (T3SS) is a macromolecular complex used by Gram-negative bacteria to secrete effector proteins from the cytoplasm across the bacterial envelope in a single step. For many pathogens, the T3SS is an essential virulence fac
Externí odkaz:
https://doaj.org/article/4461703fe2344cf4b6edeb672eb8a7e8
Autor:
Jean-Philippe Demers, Nikolaos G Sgourakis, Rashmi Gupta, Antoine Loquet, Karin Giller, Dietmar Riedel, Britta Laube, Michael Kolbe, David Baker, Stefan Becker, Adam Lange
Publikováno v:
PLoS Pathogens, Vol 9, Iss 3, p e1003245 (2013)
The Type Three Secretion System (T3SS), or injectisome, is a macromolecular infection machinery present in many pathogenic Gram-negative bacteria. It consists of a basal body, anchored in both bacterial membranes, and a hollow needle through which ef
Externí odkaz:
https://doaj.org/article/1f5dd9c0cadc4629930ceec1a46ce7c7