Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Michael Koehrsen"'
Autor:
Brian Weiner, James Gomez, Thomas C Victor, Robert M Warren, Alexander Sloutsky, Bonnie B Plikaytis, James E Posey, Paul D van Helden, Nicolass C Gey van Pittius, Michael Koehrsen, Peter Sisk, Christian Stolte, Jared White, Sebastien Gagneux, Bruce Birren, Deborah Hung, Megan Murray, James Galagan
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e26038 (2012)
Mycobacterium tuberculosis, the causative agent of most human tuberculosis, infects one third of the world's population and kills an estimated 1.7 million people a year. With the world-wide emergence of drug resistance, and the finding of more functi
Externí odkaz:
https://doaj.org/article/9d45c4662e0341f6ad7deca18843397f
Autor:
Mia D Champion, Qiandong Zeng, Eli B Nix, Francis E Nano, Paul Keim, Chinnappa D Kodira, Mark Borowsky, Sarah Young, Michael Koehrsen, Reinhard Engels, Matthew Pearson, Clint Howarth, Lisa Larson, Jared White, Lucia Alvarado, Mats Forsman, Scott W Bearden, Anders Sjöstedt, Richard Titball, Stephen L Michell, Bruce Birren, James Galagan
Publikováno v:
PLoS Pathogens, Vol 5, Iss 5, p e1000459 (2009)
Tularemia is a geographically widespread, severely debilitating, and occasionally lethal disease in humans. It is caused by infection by a gram-negative bacterium, Francisella tularensis. In order to better understand its potency as an etiological ag
Externí odkaz:
https://doaj.org/article/52a48aebe0a644238f82d11778671b61
Autor:
Florian Bihl, Raymond T. Chung, Arne Schneidewind, Edward D. Gomperts, Bruce W. Birren, Gerond Lake-Bakaar, David Heckerman, Chad Nusbaum, Zhimin Liu, Niall Lennon, Hugo R. Rosen, James E. Galagan, Bongshin Lee, Sharyne M. Donfield, Andrew Berical, Tony N. Marion, Arthur Y. Kim, Joerg Timm, Vicki M. Park, Michael Koehrsen, Andreas Cerny, Ulrich Spengler, Andrew H. Talal, Margaret A. Madey, Yanming Xing, Eric S. Daar, Laura L. Reyor, Thomas Kuntzen, Ira M. Jacobson, Bruce D. Walker, Jaquelyn Fleckenstein, Jonathan M. Carlson, Marianna Kleyman, Todd M. Allen, Matthew R. Henn, Chinnappa D. Kodira, Aaron M. Berlin, Brian R. Edlin, Timothy Ledlie, Cory M. McMahon, Georg M. Lauer, Sarah Young, Christopher E. Birch, Julian Schulze zur Wiesch, Andrew Roberts
Publikováno v:
Hepatology. 48:1769-1778
Resistance mutations to hepatitis C virus (HCV) nonstructural protein 3 (NS3) protease inhibitors in1% of the viral quasispecies may still allow1000-fold viral load reductions upon treatment, consistent with their reported reduced replicative fitness
Autor:
James E. Galagan, Giri Narasimhan, Reinhard Engels, Philip Montgomery, Kalai Mathee, Camilo Valdes, Erliang Zeng, Melissa Doud, Bruce W. Birren, Raquel Olavarietta, Jody M. Matewish, Chandri N. Yandava, Jared White, Roger S. Smith, Xiaoyun Qiu, Antonis Rokas, Michael Koehrsen, Paul A. Godfrey, Chinnappa D. Kodira, Stephen Lory
Publikováno v:
Proceedings of the National Academy of Sciences. 105:3100-3105
One of the hallmarks of the Gram-negative bacterium Pseudomonas aeruginosa is its ability to thrive in diverse environments that includes humans with a variety of debilitating diseases or immune deficiencies. Here we report the complete sequence and
Autor:
Xiaohui Xie, Liande Li, B. Gillian Turgeon, Daren W. Brown, Christina A. Cuomo, Etienne Danchin, M. Carmen Ruiz-Roldán, Ilan Wapinski, Petra M. Houterman, Aviv Regev, Sharadha Sakthikumar, Diego Miranda-Saavedra, James E. Galagan, Lokesh Kumar, Michael Koehrsen, Divya Sain, Sean M. Sykes, Martijn Rep, Yong-Hwan Lee, Chinnappa D. Kodira, Andrew C. Diener, Li-Jun Ma, B. H. Bluhm, Won-Bo Shim, Kim E. Hammond-Kosack, H. Charlotte van der Does, Jeffrey J. Coleman, Jin-Rong Xu, David C. Schwartz, John F. Antoniw, John M. Manners, Robert H. Proctor, Sook Young Park, Sinéad B. Chapman, Seogchan Kang, Liane R. Gale, Kemal Kazan, Karen Hilburn, Pedro M. Coutinho, Olen C. Yoder, Stephen A. Goff, Robert A. E. Butchko, Gyungsoon Park, Bernard Henrissat, Katherine A. Borkovich, H. Corby Kistler, Michael Freitag, Aurélie Hua-Van, Mala Mukherjee, Scott E. Baker, Shiguo Zhou, Qiandong Zeng, Donald M. Gardiner, Manfred Grabherr, Wilfried Jonkers, Marie Josée Daboussi, Marie Dufresne, Andrew Breakspear, Charles P. Woloshuk, Antonio Di Pietro, Sarah Young, Richard M.R. Coulson, Jongsun Park
Publikováno v:
Nature
Nature, Nature Publishing Group, 2010, 464 (7287), pp.367-373
Nature, 464(7287), 367-373. Nature Publishing Group
Nature, 2010, 464 (7287), pp.367-373. ⟨10.1038/nature08850⟩
Nature, Nature Publishing Group, 2010, 464 (7287), pp.367-73. ⟨10.1038/nature08850⟩
Nature, Nature Publishing Group, 2010, 464 (7287), pp.367-373
Nature, 464(7287), 367-373. Nature Publishing Group
Nature, 2010, 464 (7287), pp.367-373. ⟨10.1038/nature08850⟩
Nature, Nature Publishing Group, 2010, 464 (7287), pp.367-73. ⟨10.1038/nature08850⟩
International audience; Fusarium species are among the most important phytopathogenic and toxigenic fungi. To understand the molecular underpinnings of pathogenicity in the genus Fusarium, we compared the genomes of three phenotypically diverse speci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee2fe83657fc753869d9f7546bd26966
https://europepmc.org/articles/PMC3048781/
https://europepmc.org/articles/PMC3048781/
Autor:
Zachariah K. Zachariah, Reinhard Engels, Brian Weiner, Heng Jin, Michael Nitzberg, Jared White, Christian Stolte, Maria Mao, Lisa Larson, Farrell Wymore, James E. Galagan, Jeremy Hubble, T. B. K. Reddy, Catherine A. Ball, Michael Koehrsen, Gavin Sherlock, Marcel Gellesch, Peter Sisk, Jeremy Zucker, Gary K. Schoolnik
Publikováno v:
Tuberculosis (Edinburgh, Scotland). 90(4)
summary The Tuberculosis Database (TBDB) is an online database providing integrated access to genome sequence, expression data and literature curation for TB. TBDB currently houses genome assemblies for numerous strains of Mycobacterium tuberculosis
Autor:
Stephen L. Michell, Francis E. Nano, James E. Galagan, Mats Forsman, Jared White, Richard W. Titball, Michael Koehrsen, Scott W. Bearden, Chinnappa D. Kodira, Anders Sjöstedt, Qiandong Zeng, Reinhard Engels, Eli B. Nix, Sarah Young, Bruce W. Birren, Clint Howarth, Matthew D. Pearson, Lisa Larson, Mia D. Champion, Mark L. Borowsky, Lucia Alvarado, Paul Keim
Publikováno v:
PLoS Pathogens, Vol 5, Iss 5, p e1000459 (2009)
PLoS Pathogens
PLoS Pathogens
Tularemia is a geographically widespread, severely debilitating, and occasionally lethal disease in humans. It is caused by infection by a gram-negative bacterium, Francisella tularensis. In order to better understand its potency as an etiological ag
Autor:
Maria Mao, Michael Nitzberg, Brian Weiner, Robert Riley, James E. Galagan, Marcel Gellesch, David DeCaprio, Reinhard Engels, Phillip Montgomery, Dennis Jen, Lisa Larson, Jeremy Hubble, Peter Sisk, Michael Koehrsen, Heng Jin, Jared White, T. B. K. Reddy, Catherine A. Ball, Farrell Wymore, Gary K. Schoolnik, Gavin Sherlock, Christian Stolte, Zachariah K. Zachariah
Publikováno v:
Nucleic Acids Research
The effective control of tuberculosis (TB) has been thwarted by the need for prolonged, complex and potentially toxic drug regimens, by reliance on an inefficient vaccine and by the absence of biomarkers of clinical status. The promise of the genomic
Autor:
Nicolass C. Gey van Pittius, Sebastien Gagneux, Robert M. Warren, James Gomez, Brian Weiner, Paul D. van Helden, James E. Posey, Deborah T. Hung, Bonnie B. Plikaytis, Peter Sisk, Alexander Sloutsky, Michael Koehrsen, Thomas C. Victor, Christian Stolte, Megan Murray, James E. Galagan, Jared White, Bruce W. Birren
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e26038 (2012)
PloS one
PLoS ONE
PloS one
PLoS ONE
Mycobacterium tuberculosis, the causative agent of most human tuberculosis, infects one third of the world's population and kills an estimated 1.7 million people a year. With the world-wide emergence of drug resistance, and the finding of more functi
Autor:
Jan Claesen, Andrej Sali, Eriko Takano, Bruce W. Birren, Marnix H. Medema, Peter Cimermancic, Paul A. Godfrey, Michael A. Fischbach, Roger G. Linington, Kenji L. Kurita, Michael Koehrsen, Laura C. Brown, Amrita Pati, Jon Clardy, Konstantinos Mavrommatis
Publikováno v:
Cell, 158(2), 412-421. CELL PRESS
Cell, vol 158, iss 2
Cell, vol 158, iss 2
SummaryAlthough biosynthetic gene clusters (BGCs) have been discovered for hundreds of bacterial metabolites, our knowledge of their diversity remains limited. Here, we used a novel algorithm to systematically identify BGCs in the extensive extant mi