Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Michael Karimov"'
Publikováno v:
Nanomaterials, Vol 10, Iss 9, p 1809 (2020)
The delivery of small interfering RNAs (siRNA) is an efficient method for gene silencing through the induction of RNA interference (RNAi). It critically relies, however, on efficient vehicles for siRNA formulation, for transfection in vitro as well a
Externí odkaz:
https://doaj.org/article/72bf15517e7b4e0486dce299967652c9
Autor:
Małgorzata Kubczak, Sylwia Michlewska, Michael Karimov, Alexander Ewe, Achim Aigner, Maria Bryszewska, Maksim Ionov
Publikováno v:
Nanotoxicology. 16:867-882
Publikováno v:
Biotechnology Journal. 18
Classical two-dimensional (2D) cell culture as a drug or nanoparticle test system only poorly recapitulates in vivo conditions. Animal studies are costly, ethically controversial, and preclude large-scale testing.We established a three-dimensional (3
Autor:
Willi Jugel, Stefanie Tietze, Jennifer Daeg, Dietmar Appelhans, Felix Broghammer, Achim Aigner, Michael Karimov, Gabriele Schackert, Achim Temme
Publikováno v:
Cancers; Volume 14; Issue 8; Pages: 1925
Among non-viral vectors, cationic polymers, such as poly(propylene imine) (PPI), play a prominent role in nucleic acid delivery. However, limitations of polycationic polymer-based DNA delivery systems are (i) insufficient target specificity, (ii) uns
Publikováno v:
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 161
Efficient and non-toxic DNA delivery is still a major limiting factor for non-viral gene therapy. Among the large diversity of non-viral vectors, the cationic polymer polyethylenimine (PEI) plays a prominent role in nucleic acid delivery. Since highe
Autor:
Sandra, Noske, Michael, Karimov, Max, Hansen, Nathalie, Zatula, Alexander, Ewe, Achim, Aigner
Publikováno v:
International Journal of Pharmaceutics. 612:121359
Mesenchymal stromal cells (MSCs) are multipotent cells derived from different sources and able to differentiate into distinct cell lineages. For their possible biomedical application, the "tuning" of MSCs also involves the specific knockdown of defin
Autor:
Heike Franke, Maksim Ionov, Małgorzata Kubczak, Michael Karimov, Ines Gockel, Tim Kahl, Marion Schulz, Alexander Ewe, Achim Aigner, Maria Bryszewska, Ute Krügel, René Thieme, Sandra Noske, Thomas Büch, Anja Reinert
Publikováno v:
Nanomedicine: Nanotechnology, Biology and Medicine. 36:102403
Therapeutic gene silencing by RNA interference relies on the safe and efficient in vivo delivery of small interfering RNAs (siRNAs). Polyethylenimines are among the most studied cationic polymers for gene delivery. For several reasons including super
Publikováno v:
Nanomaterials
Nanomaterials, Vol 10, Iss 1809, p 1809 (2020)
Volume 10
Issue 9
Nanomaterials, Vol 10, Iss 1809, p 1809 (2020)
Volume 10
Issue 9
The delivery of small interfering RNAs (siRNA) is an efficient method for gene silencing through the induction of RNA interference (RNAi). It critically relies, however, on efficient vehicles for siRNA formulation, for transfection in vitro as well a