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pro vyhledávání: '"Michael Kardorff"'
Autor:
Parthive H. Patel, Clothilde Pénalva, Michael Kardorff, Marianne Roca, Bojana Pavlović, Anja Thiel, Aurelio A. Teleman, Bruce A. Edgar
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Epithelia are exposed to diverse types of environmental stress, but the mechanisms by which epithelial cells sense stress are not well understood. Here, the authors show that a Nox-ROS-Ask1-MKK3-p38 signaling axis integrates various types of stress t
Externí odkaz:
https://doaj.org/article/53418b588147421790d9a80c1509a940
Autor:
Aurelio A. Teleman, Bojana Pavlovic, Michael Kardorff, Clothilde Pénalva, Anja Thiel, Bruce A. Edgar, Parthive H. Patel, Marianne Roca
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Patel, P H, Pénalva, C, Kardorff, M, Roca, M, Pavlović, B, Thiel, A, Teleman, A A & Edgar, B A 2019, ' Damage sensing by a Nox-Ask1-MKK3-p38 signaling pathway mediates regeneration in the adult Drosophila midgut ', Nature Communications, vol. 10, no. 1, 4365 (2019) . https://doi.org/10.1038/s41467-019-12336-w
Nature Communications
Patel, P H, Pénalva, C, Kardorff, M, Roca, M, Pavlović, B, Thiel, A, Teleman, A A & Edgar, B A 2019, ' Damage sensing by a Nox-Ask1-MKK3-p38 signaling pathway mediates regeneration in the adult Drosophila midgut ', Nature Communications, vol. 10, 4365 (2019) . https://doi.org/10.1038/s41467-019-12336-w
Patel, P H, Pénalva, C, Kardorff, M, Roca, M, Pavlović, B, Thiel, A, Teleman, A A & Edgar, B A 2019, ' Damage sensing by a Nox-Ask1-MKK3-p38 signaling pathway mediates regeneration in the adult Drosophila midgut ', Nature Communications, vol. 10, no. 1, 4365 (2019) . https://doi.org/10.1038/s41467-019-12336-w
Nature Communications
Patel, P H, Pénalva, C, Kardorff, M, Roca, M, Pavlović, B, Thiel, A, Teleman, A A & Edgar, B A 2019, ' Damage sensing by a Nox-Ask1-MKK3-p38 signaling pathway mediates regeneration in the adult Drosophila midgut ', Nature Communications, vol. 10, 4365 (2019) . https://doi.org/10.1038/s41467-019-12336-w
Epithelia are exposed to diverse types of stress and damage from pathogens and the environment, and respond by regenerating. Yet, the proximal mechanisms that sense epithelial damage remain poorly understood. Here we report that p38 signaling is acti