Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Michael K. Strasser"'
Autor:
Michael K. Strasser, Philipp S. Hoppe, Dirk Loeffler, Konstantinos D. Kokkaliaris, Timm Schroeder, Fabian J. Theis, Carsten Marr
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
The timing of cell fate choices is usually unknown, because we have to rely on indirect evidence of their molecular basis. Here, the authors introduce a method to infer decision times from marker onset in cell genealogies, and find evidence refuting
Externí odkaz:
https://doaj.org/article/983bff561cd148d39c9c6755fd3f3b03
Autor:
Lisa Bast, Filippo Calzolari, Michael K. Strasser, Jan Hasenauer, Fabian J. Theis, Jovica Ninkovic, Carsten Marr
Publikováno v:
Cell Reports, Vol 25, Iss 12, Pp 3231-3240.e8 (2018)
Summary: Adult murine neural stem cells (NSCs) generate neurons in drastically declining numbers with age. How cellular dynamics sustain neurogenesis and how alterations with age may result in this decline are unresolved issues. We therefore clonally
Externí odkaz:
https://doaj.org/article/038a8031005044c7a9149a66f8672bb6
MotivationGene set scoring is a common task in bioinformatics, but the sparsity of data points in single cell gene expression creates difficulties.ResultsBy applying matrix smoothing to the nearest neighbor graph of cells, high quality gene set score
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e2bfebd669a7c63e424a20a740392c4f
https://doi.org/10.1101/2022.11.29.518384
https://doi.org/10.1101/2022.11.29.518384
Publikováno v:
Physical Biology; Jun2017, Vol. 14 Issue 3, p1-1, 1p
Autor:
Kaitlyn E Johnson, Grant Howard, William Mo, Michael K Strasser, Ernesto A B F Lima, Sui Huang, Amy Brock
Publikováno v:
PLoS Biology, Vol 17, Iss 8, p e3000399 (2019)
Most models of cancer cell population expansion assume exponential growth kinetics at low cell densities, with deviations to account for observed slowing of growth rate only at higher densities due to limited resources such as space and nutrients. Ho
Externí odkaz:
https://doaj.org/article/b9865c052a504627a1961fd4354b951f