Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Michael K. Connolly"'
Publikováno v:
Clinical toxicology (Philadelphia, Pa.). 59(3)
Severe baclofen toxicity can result in respiratory failure, hemodynamic instability, bradycardia, hypothermia, seizures, coma, and death. While hemodialysis (HD) is well-described in treating acute baclofen toxicity in patients with end-stage kidney
Publikováno v:
Pediatric Annals. 46
The American Association of Poison Control Centers' National Poison Data Surveillance System provides real-time toxico-surveillance and epidemiologic trends, and pediatric ingestions comprise most of those reports. The sequences in social and physica
Autor:
Jonathan E. Grob, Ronald Tomlinson, Ritesh Bhanudasji Tichkule, Michael A. Dechantsreiter, Michael K. Connolly, Ayako Honda, Lawrence G. Hamann
Publikováno v:
Organic Letters. 14:5578-5581
Iterative cross-coupling is a highly efficient and versatile strategy for modular construction in organic synthesis, though this has historically been demonstrated solely in the context of C-C bond formation. A C-N cross-coupling of haloarene methyli
Autor:
H. Leon Pachter, Ashim Malhotra, Andrew Nguyen, Andrea S. Bedrosian, Napoleon E. Cieza-Rubio, Justin R. Henning, Michael K. Connolly, Monica Dorvil-Castro, Michael Hackman, Junaid Ibrahim, George Miller, Diego Ayo
Publikováno v:
Hepatology. 54:959-968
Acetaminophen (APAP) overdose is one of the most frequent causes of acute liver failure in the United States and is primarily mediated by toxic metabolites that accumulate in the liver upon depletion of glutathione stores. However, cells of the innat
Autor:
Alan B. Frey, Steven P. Cohen, Valery Vera, H. Leon Pachter, George Miller, Michael K. Connolly, Justin R. Henning, Ashim Malhotra, Burhan U. Hassan, Junaid Ibrahim, Napoleon E. Cieza-Rubio, Andrea S. Bedrosian
Publikováno v:
The Journal of Immunology. 185:2200-2208
The normal liver is characterized by immunologic tolerance. Primary mediators of hepatic immune tolerance are liver sinusoidal endothelial cells (LSECs). LSECs block adaptive immunogenic responses to Ag and induce the generation of T regulatory cells
Autor:
Valery Vera, Michael K. Connolly, Alan B. Frey, Dafna Bar-Sagi, Jon Mallen-St. Clair, Ashim Malhotra, Justin R. Henning, Junaid Ibrahim, George Miller, H. Leon Pachter, Andrea S. Bedrosian
Publikováno v:
Journal of Leukocyte Biology. 87:713-725
The expansion of distinct immune suppressive cells in the liver of tumor bearing hosts may bear on the propensity of patients with intra-abdominal cancers to develop liver metastases. The liver is the most common site of adenocarcinoma metastases, ev
Autor:
Lawrence G. Hamann, Jonathan E. Grob, Ronald Tomlinson, Michael K. Connolly, Ritesh Bhanudasji Tichkule, Ayako Honda, Michael A. Dechantsreiter
Publikováno v:
ChemInform. 44
In the presence of PAP and K3PO4 or LiHMDS, boronyl arenes undergo convenient amination to afford a wide range of arylamines.
Autor:
Junaid Ibrahim, George Miller, Adeel Rehman, Rocky Barilla, Devrim Acehan, Alan B. Frey, Marco V. Medina-Zea, Michael Hackman, Steven M. Cohen, Andrea S. Bedrosian, Napoleon E. Cieza-Rubio, Michael K. Connolly, Justin R. Henning, H. Leon Pachter, Ashim Malhotra, Andrew Nguyen
Publikováno v:
Gastroenterology. 141(5)
Background & Aims The cellular mediators of acute pancreatitis are incompletely understood. Dendritic cells (DCs) can promote or suppress inflammation, depending on their subtype and context. We investigated the roles of DC in development of acute pa
Autor:
Michael K. Connolly, George Miller, Andrea Stroud, Dafna Bar-Sagi, H. Leon Pachter, Alan B. Frey, Andrea S. Bedrosian, Aaron P. Mitchell, Junaid Ibrahim, Jon Mallen-St. Clair
Publikováno v:
The Journal of clinical investigation. 119(11)
Hepatic fibrosis occurs during most chronic liver diseases and is driven by inflammatory responses to injured tissue. Because DCs are central to modulating liver immunity, we postulated that altered DC function contributes to immunologic changes in h
Autor:
George Miller, Michael K. Connolly, Steven P. Cohen, Anya Romanoff, Junaid Ibrahim, Andrea S. Bedrosian
Publikováno v:
Journal of the American College of Surgeons. 211:S122-S123