Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Michael K. Wismer"'
Autor:
Jonas Rein, James R. Annand, Michael K. Wismer, Jiantao Fu, Juno C. Siu, Artis Klapars, Neil A. Strotman, Dipannita Kalyani, Dan Lehnherr, Song Lin
Publikováno v:
ACS Central Science, Vol 7, Iss 8, Pp 1347-1355 (2021)
Externí odkaz:
https://doaj.org/article/d3f7426863554b8e880430b2f4aab67a
A General Small-Scale Reactor To Enable Standardization and Acceleration of Photocatalytic Reactions
Autor:
Chi “Chip” Le, Michael K. Wismer, Zhi-Cai Shi, Rui Zhang, Donald V. Conway, Guoqing Li, Petr Vachal, Ian W. Davies, David W. C. MacMillan
Publikováno v:
ACS Central Science, Vol 3, Iss 6, Pp 647-653 (2017)
Externí odkaz:
https://doaj.org/article/355e301843374f69939e53056a9ec5f8
Autor:
Cecilia Bottecchia, Dan Lehnherr, François Lévesque, Mikhail Reibarkh, Yining Ji, Vailankanni L. Rodrigues, Heather Wang, Yu-hong Lam, Thomas P. Vickery, Brittany M. Armstrong, Keith A. Mattern, Kevin Stone, Michael K. Wismer, Andrew N. Singh, Erik L. Regalado, Kevin M. Maloney, Neil A. Strotman
Publikováno v:
Organic Process Research & Development. 26:2423-2437
Publikováno v:
Reaction Chemistry & Engineering. 7:354-360
Enhanced reactivity of decarboxylative cross-coupling using a new parallel photoreactor.
Autor:
Glenn Spencer, Michael K. Wismer, Karthik Narsimhan, Lushi Tan, Cecilia Bottecchia, Jonathan P. McMullen, Yining Ji, Dan Lehnherr, Mikhail Reibarkh, Stephen M. Dalby, Like Chen, Feng Peng, Yipeng Lin, François Lévesque, Jarod Nappi
Publikováno v:
Organic Process Research & Development. 26:516-524
We report the development and scale-up of a continuous flow photochemical benzylic bromination en route to belzutifan (MK-6482), a small molecule for the treatment of renal cell carcinoma associate...
Autor:
Michael K. Wismer, Dan Lehnherr, Jonas Rein, Neil A. Strotman, Artis Klapars, Song Lin, Dipannita Kalyani, Jiantao Fu, Juno C. Siu, James R. Annand
Publikováno v:
ACS Central Science, Vol 7, Iss 8, Pp 1347-1355 (2021)
ACS Central Science
ACS Central Science
Organic electrochemistry has emerged as an enabling and sustainable technology in modern organic synthesis. Despite the recent renaissance of electrosynthesis, the broad adoption of electrochemistry in the synthetic community, and especially in indus
Publikováno v:
Organic Process Research & Development. 24:2935-2940
A simple and inexpensive photoreactor with a throughput of kilograms of material per day has been developed. This achievement was enabled by using high-power Light Emitting Diodes (LEDs) to provide...
Publikováno v:
Angewandte Chemie. 132:12062-12066
With the development of new photocatalytic methods over recent decades, the translation of these chemical reactions to industrial-production scales using continuous-flow reactors has become a topic of increasing interest. In this context, we describe
Autor:
Paul N. Devine, Ian Mangion, Benjamin F. Mann, Shuwen Sun, Erik D. Guetschow, Christopher J. Welch, Michael K. Wismer, Jeffrey C. Moore, Daniel A. Holland‐Moritz, Iman Farasat, Robert T. Kennedy
Publikováno v:
Angewandte Chemie International Edition. 59:4470-4477
Microfluidic droplet sorting enables the high-throughput screening and selection of water-in-oil microreactors at speeds and volumes unparalleled by traditional well-plate approaches. Most such systems sort using fluorescent reporters on modified sub
Autor:
Zufei Zhang, Mary Motyl, Hwa-Ping Feng, Michael K. Wismer, Katherine Young, Qian Si, Fred Racine, Matthew G. Johnson, Matthew L. Rizk, Jing Chen Xiao, Donna Carr, Ravi Katwaru
Publikováno v:
Open Forum Infectious Diseases
Our hollow-fiber infection model simulated the projected steady-state pharmacokinetics of ceftolozane and tazobactam in lung epithelial lining fluid of patients with pneumonia receiving 3 g of ceftolozane/tazobactam every 8 hours. Results confirmed t