Zobrazeno 1 - 10
of 245
pro vyhledávání: '"Michael K Richardson"'
Autor:
Freek J Vonk, Mátyás A Bittenbinder, Harald M I Kerkkamp, Dwin G B Grashof, John P Archer, Sandra Afonso, Michael K Richardson, Jeroen Kool, Arie van der Meijden
Publikováno v:
PLoS ONE, Vol 16, Iss 11, p e0258712 (2021)
Scorpion venoms are mixtures of proteins, peptides and small molecular compounds with high specificity for ion channels and are therefore considered to be promising candidates in the venoms-to-drugs pipeline. Transcriptomes are important tools for st
Externí odkaz:
https://doaj.org/article/9647148e57444214ad232b3792d6f47b
Autor:
Benjamin J van Soldt, Brian D Metscher, Robert E Poelmann, Bart Vervust, Freek J Vonk, Gerd B Müller, Michael K Richardson
Publikováno v:
PLoS ONE, Vol 10, Iss 1, p e116416 (2015)
Snake lungs show a remarkable diversity of organ asymmetries. The right lung is always fully developed, while the left lung is either absent, vestigial, or well-developed (but smaller than the right). A 'tracheal lung' is present in some taxa. These
Externí odkaz:
https://doaj.org/article/9cf818968e454250b48d55f5ad7eeca8
Autor:
Tabitha S Rudin-Bitterli, Oliver Tills, John I Spicer, Phil F Culverhouse, Eric M Wielhouwer, Michael K Richardson, Simon D Rundle
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e113235 (2014)
Small, early life stages, such as zebrafish embryos are increasingly used to assess the biological effects of chemical compounds in vivo. However, behavioural screens of such organisms are challenging in terms of both data collection (culture techniq
Externí odkaz:
https://doaj.org/article/bc32a1d1f5814f37abb49ad6b2c30441
Autor:
Robert E Poelmann, Adriana C Gittenberger-de Groot, Rebecca Vicente-Steijn, Lambertus J Wisse, Margot M Bartelings, Sonja Everts, Tamara Hoppenbrouwers, Boudewijn P T Kruithof, Bjarke Jensen, Paul W de Bruin, Tatsuya Hirasawa, Shigeru Kuratani, Freek Vonk, Jeanne M M S van de Put, Merijn A de Bakker, Michael K Richardson
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e106569 (2014)
During cardiogenesis the epicardium, covering the surface of the myocardial tube, has been ascribed several functions essential for normal heart development of vertebrates from lampreys to mammals. We investigated a novel function of the epicardium i
Externí odkaz:
https://doaj.org/article/52dcefcf980145e5b2b5d1b1e3de40ec
Autor:
Meiru Wang, Shuhao Chen, Shixiong Cheng, Tom A.P. Nederstigt, Robert E. Poelmann, Marco C. DeRuiter, Gerda E.M. Lamers, Joost J. Willemse, Chiara Mascitelli, Martina G. Vijver, Michael K. Richardson
Publikováno v:
Environment International, Vol 188, Iss , Pp 108723- (2024)
Nanoplastics can cause severe malformations in chicken embryos. To improve our understanding of the toxicity of nanoplastics to embryos, we have studied their biodistribution in living chicken embryos. We injected the embryos in the vitelline vein at
Externí odkaz:
https://doaj.org/article/f39ba361ead14df896bcc88cf5f2972b
Publikováno v:
PLoS ONE, Vol 6, Iss 5, p e20037 (2011)
BACKGROUND: In humans, ethanol exposure during pregnancy causes a spectrum of developmental defects (fetal alcohol syndrome or FAS). Individuals vary in phenotypic expression. Zebrafish embryos develop FAS-like features after ethanol exposure. In thi
Externí odkaz:
https://doaj.org/article/385f7a28db3a43769102d741d5c26e20
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e21076 (2011)
BACKGROUND: In the drug discovery pipeline, safety pharmacology is a major issue. The zebrafish has been proposed as a model that can bridge the gap in this field between cell assays (which are cost-effective, but low in data content) and rodent assa
Externí odkaz:
https://doaj.org/article/e8994bc5307d4f84b8373180c50c0043
Autor:
Meiru Wang, Martin Rücklin, Robert E. Poelmann, Carmen L. de Mooij, Marjolein Fokkema, Gerda E.M. Lamers, Merijn A.G. de Bakker, Ernest Chin, Lilla J. Bakos, Federica Marone, Bert J. Wisse, Marco C. de Ruiter, Shixiong Cheng, Luthfi Nurhidayat, Martina G. Vijver, Michael K. Richardson
Publikováno v:
Environment International, Vol 173, Iss , Pp 107865- (2023)
Nanomaterials are widespread in the human environment as pollutants, and are being actively developed for use in human medicine. We have investigated how the size and dose of polystyrene nanoparticles affects malformations in chicken embryos, and hav
Externí odkaz:
https://doaj.org/article/f172de64c5f64b42824c1716671e332e
Autor:
Robert E. Poelmann, Adriana C. Gittenberger-de Groot, Marcel W. M. Biermans, Anne I. Dolfing, Armand Jagessar, Sam van Hattum, Amanda Hoogenboom, Lambertus J. Wisse, Rebecca Vicente-Steijn, Merijn A. G. de Bakker, Freek J. Vonk, Tatsuya Hirasawa, Shigeru Kuratani, Michael K. Richardson
Publikováno v:
EvoDevo, Vol 8, Iss 1, Pp 1-17 (2017)
Abstract Background Cardiac outflow tract patterning and cell contribution are studied using an evo-devo approach to reveal insight into the development of aorto-pulmonary septation. Results We studied embryonic stages of reptile hearts (lizard, turt
Externí odkaz:
https://doaj.org/article/6facba4458b147179aae26a24ddccbcf
Publikováno v:
Journal of Comparative Neurology, 530(12), 2132-2153. WILEY
Bitterlings are carp-like teleost fish (Cypriniformes: Acheilanathidae) known for their specialized brood parasitic lifestyle. Bitterling embryos, in fact, develop inside the gill chamber of their freshwater mussel hosts. However, little is known abo