Zobrazeno 1 - 10
of 224
pro vyhledávání: '"Michael K Racke"'
Autor:
Nancy L Monson, Petra Cravens, Rehana Hussain, Christopher T Harp, Matthew Cummings, Maria de Pilar Martin, Li-Hong Ben, Julie Do, Jeri-Anne Lyons, Amy Lovette-Racke, Anne H Cross, Michael K Racke, Olaf Stüve, Mark Shlomchik, Todd N Eagar
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e17103 (2011)
Recent clinical trials have established B cell depletion by the anti-CD20 chimeric antibody Rituximab as a beneficial therapy for patients with relapsing-remitting multiple sclerosis (MS). The impact of Rituximab on T cell responses remains largely u
Externí odkaz:
https://doaj.org/article/7eb457a109ad42ca8f3e5a28c0d1260d
Autor:
Wei Hu, Josbert Metselaar, Li-Hong Ben, Petra D Cravens, Mahendra P Singh, Elliot M Frohman, Todd N Eagar, Michael K Racke, Bernd C Kieseier, Olaf Stüve
Publikováno v:
PLoS ONE, Vol 4, Iss 1, p e4151 (2009)
Minocycline is an oral tetracycline derivative with good bioavailability in the central nervous system (CNS). Minocycline, a potent inhibitor of matrix metalloproteinase (MMP)-9, attenuates disease activity in experimental autoimmune encephalomyeliti
Externí odkaz:
https://doaj.org/article/10b2eb9295b549ceaada9a6ad5a4749d
Autor:
Karen Yao, Susan Gagnon, Nahid Akhyani, Elizabeth Williams, Julie Fotheringham, Elliot Frohman, Olaf Stuve, Nancy Monson, Michael K Racke, Steven Jacobson
Publikováno v:
PLoS ONE, Vol 3, Iss 4, p e2028 (2008)
The alpha(4) integrin antagonist natalizumab was shown to be effective in patients with immune-mediated disorders but was unexpectedly associated with JC polyomavirus associated progressive multifocal leukoencephalopathy (PML) in two multiple scleros
Externí odkaz:
https://doaj.org/article/d375c61675a14e448828e19c8729731f
Autor:
Darren M. Weber, Steven W. Taylor, Robert J. Lagier, Jueun C. Kim, Scott M. Goldman, Nigel J. Clarke, David E. Vaillancourt, Ranjan Duara, Karen N. McFarland, Wei-en Wang, Todd E. Golde, Michael K. Racke
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
IntroductionPlasma Aβ42/40 ratio can help predict amyloid PET status, but its clinical utility in Alzheimer’s disease (AD) assessment is unclear.MethodsAβ42/40 ratio was measured by LC-MS/MS for 250 specimens with associated amyloid PET imaging,
Externí odkaz:
https://doaj.org/article/9e471991a0474d5183e46f090a18bcfb
Autor:
Hiromitsu Asashima, Dongjoo Kim, Kaicheng Wang, Nikhil Lele, Nicholas C. Buitrago-Pocasangre, Rachel Lutz, Isabella Cruz, Khadir Raddassi, William E. Ruff, Michael K. Racke, JoDell E. Wilson, Tara S. Givens, Alba Grifoni, Daniela Weiskopf, Alessandro Sette, Steven H. Kleinstein, Ruth R. Montgomery, Albert C. Shaw, Fangyong Li, Rong Fan, David A. Hafler, Mary M. Tomayko, Erin E. Longbrake
Publikováno v:
JCI Insight, Vol 8, Iss 16 (2023)
BACKGROUND While B cell depletion is associated with attenuated antibody responses to SARS-CoV-2 mRNA vaccination, responses vary among individuals. Thus, elucidating the factors that affect immune responses after repeated vaccination is an important
Externí odkaz:
https://doaj.org/article/b06e7d12199f424e988db974eca28074
Autor:
Lukasz S. Wylezinski, Guzel I. Shaginurova, Elena V. Grigorenko, Jay G. Wohlgemuth, Franklin R. Cockerill, Michael K. Racke, Charles F. Spurlock
Publikováno v:
Sunday, April 23.
Publikováno v:
Alzheimer's & Dementia. 18
Autor:
Dongjoo Kim, Giulia Biancon, Zhiliang Bai, Jennifer VanOudenhove, Yuxin Liu, Shalin Kothari, Lohith Gowda, Jennifer M. Kwan, Nicholas Carlos Buitrago-Pocasangre, Nikhil Lele, Hiromitsu Asashima, Michael K. Racke, JoDell E. Wilson, Tara S. Givens, Mary M. Tomayko, Wade L. Schulz, Erin E. Longbrake, David A. Hafler, Stephanie Halene, Rong Fan
Publikováno v:
bioRxiv : the preprint server for biology.
The immune response to SARS-CoV-2 for patients with altered immunity such as hematologic malignancies and autoimmune disease may differ substantially from that in general population. These patients remain at high risk despite wide-spread adoption of
Publikováno v:
Journal of neuroimmunology. 371
Autor:
Carolyn Goldschmidt, Steven L. Galetta, Robert P. Lisak, Laura J. Balcer, Andrew Hellman, Michael K. Racke, Amy E. Lovett-Racke, Roberto Cruz, Matthew S. Parsons, Neda Sattarnezhad, Lawrence Steinman, Scott S. Zamvil, Elliot M. Frohman, Teresa C. Frohman
Publikováno v:
Neurology(R) neuroimmunologyneuroinflammation. 10(1)
A woman presented at age 18 years with partial myelitis and diplopia and experienced multiple subsequent relapses. Her MRI demonstrated T2 abnormalities characteristic of multiple sclerosis (MS) (white matter ovoid lesions and Dawson fingers), and CS