Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Michael K Delaney"'
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 37
Platelets promote coagulation mainly by exposing membrane phosphatidylserine (PS) and releasing PS-expressing microvesicles (MV). We have recently shown that PS exposure and MV release induced by platelet agonists requires shear stress. To identify t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe8835a413f95f4a52baa9c16f04f77b
https://doi.org/10.1161/atvb.37.suppl_1.51
https://doi.org/10.1161/atvb.37.suppl_1.51
Autor:
Jaehyung Cho, Bo Shen, Aleksandra Stojanovic-Terpo, Michael K Delaney, Xiaoping Du, Kyungho Kim, Brian Estevez, Masuko Ushio-Fukai
Publikováno v:
Circulation. 132
Objective: Reactive oxygen species (ROS) generated from activated platelets is known to regulate platelet activation. However, it remains unclear whether and how different isoforms of nicotinamide adenine dinucleotide (phosphate) (NAD(P)H) oxidases (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dafee1c6713f43ceb8deb3a8106e17b8
https://doi.org/10.1161/circ.132.suppl_3.19967
https://doi.org/10.1161/circ.132.suppl_3.19967
Publikováno v:
Circulation. 130
Numerous reports indicate that the platelet glycoprotein (GP) Ib-IX complex (GPIb-IX) binds directly to the potent platelet agonist thrombin and is important for promoting thrombin-induced platelet activation. However, how GPIb-IX contributes to thro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::737824e7230f8fadfb2e8e180530c389
https://doi.org/10.1161/circ.130.suppl_2.11947
https://doi.org/10.1161/circ.130.suppl_2.11947
Autor:
Junling Liu, Michael K Delaney, Xiaoping Du, Kyungho Kim, Yi Zheng, Aleksandra Stojanovic-Terpo, Jaehyung Cho, Bo Shen
Publikováno v:
Blood. 124(12)
Activated platelets facilitate blood coagulation by exposing phosphatidylserine (PS) and releasing microvesicles (MVs). However, the potent physiological agonists thrombin and collagen poorly induce PS exposure when a single agonist is used. To obtai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ab22944e2ff1b73b21cd21d5ad528b1
https://pubmed.ncbi.nlm.nih.gov/25079357
https://pubmed.ncbi.nlm.nih.gov/25079357
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 32
The platelet receptor for von Willebrand factor (VWF), the glycoprotein Ib-IX (GPIb-IX) complex, mediates platelet adhesion at sites of vascular injury and transmits signals leading to platelet activation. Ligand occupancy of GPIb-IX stimulates the s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff90dd0fc27fe2f834e0e723f1872a0f
https://doi.org/10.1161/atvb.32.suppl_1.a499
https://doi.org/10.1161/atvb.32.suppl_1.a499
Publikováno v:
Blood. 124:2759-2759
Numerous reports indicate that the platelet glycoprotein (GP) Ib-IX complex (GPIb-IX) binds directly to the potent platelet agonist thrombin and is important for promoting thrombin-induced platelet activation. However, how GPIb-IX contributes to thro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb3b0d0f7b7ed8014ff15ccd0b46f863
https://doi.org/10.1182/blood.v124.21.2759.2759
https://doi.org/10.1182/blood.v124.21.2759.2759
Autor:
Michael K Delaney, Aleksandra Stojanovic-Terpo, Jaehyung Cho, Xiaojuan Zhao, Kelly A. O'Brien, Xiaoping Du, Kyungho Kim, Bo Shen, Stephen C.-T. Lam
Publikováno v:
Blood. 122:2295-2295
Antagonists of platelet integrin alphaIIbbeta3 are potent anti-thrombotics due to critical roles of integrins in thrombosis. However, integrins are also important in hemostasis, and thus integrin antagonists have potentially life-threatening bleeding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f30db6aed6db6ad625fc1dacf2e4544
https://doi.org/10.1182/blood.v122.21.2295.2295
https://doi.org/10.1182/blood.v122.21.2295.2295
Autor:
Michael K Delaney
Publikováno v:
Blood. 118:3250-3250
Abstract 3250 The platelet receptor for von Willebrand factor, the glycoprotein Ib-IX (GPIb-IX) complex, not only plays a critical role in mediating platelet adhesion at sites of vascular injury, but also transmits signals leading to platelet activat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::14e703321b8d4fe9179a58272b66f277
https://doi.org/10.1182/blood.v118.21.3250.3250
https://doi.org/10.1182/blood.v118.21.3250.3250