Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Michael Joseph Urban"'
Autor:
Michael Joseph Urban, Rick T. Dobrowsky, Pan Pan, Brian S. J. Blagg, Jiacheng Ma, Huiping Zhao, Kevin L. Farmer
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 348:281-292
Impaired neuronal mitochondrial bioenergetics contributes to the pathophysiologic progression of diabetic peripheral neuropathy (DPN) and may be a focal point for disease management. We have demonstrated that modulating heat shock protein (Hsp) 90 an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e96eb855dfe416ca5395e72ad0b9d731
https://doi.org/10.1124/jpet.113.210435
https://doi.org/10.1124/jpet.113.210435
Autor:
Rick T. Dobrowsky, Michael Joseph Urban, Pan Pan, Kevin L. Farmer, Brian S. J. Blagg, Huiping Zhao
Quantification of intra-epidermal nerve fibers (iENFs) is an important approach to stage diabetic peripheral neuropathy (DPN) and is a promising clinical endpoint for identifying beneficial therapeutics. Mechanistically, diabetes decreases neuronal m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::788a2e472d22d2147c348582801c6af8
https://europepmc.org/articles/PMC3336191/
https://europepmc.org/articles/PMC3336191/
Dysfunctional insulin and insulin-like growth factor-I (IGF-I) signaling contributes to the pathological progression of diabetes, diabetic peripheral neuropathy (DPN), Alzheimer's (AD), Parkinson's (PD) and Huntington's diseases (HD). Despite their p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1757ec676a6a2fa2b88a037911b1369
https://europepmc.org/articles/PMC3319453/
https://europepmc.org/articles/PMC3319453/
Autor:
Roger A. Rajewski, Rick T. Dobrowsky, Michael Joseph Urban, Brian S. J. Blagg, Michelle P. McIntosh, Cuijuan Yu, Joanna Krise, Yuanming Lu, Chengyuan Li
Publikováno v:
ASN NEURO
ASN Neuro, Vol 2 (2010)
ASN Neuro, Vol 2 (2010)
Increasing the expression of Hsp70 (heat-shock protein 70) can inhibit sensory neuron degeneration after axotomy. Since the onset of DPN (diabetic peripheral neuropathy) is associated with the gradual decline of sensory neuron function, we evaluated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc8d0090fcc341f67aa1d1f75a3dea41
https://pubmed.ncbi.nlm.nih.gov/20842208
https://pubmed.ncbi.nlm.nih.gov/20842208