Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Michael Jonathan Lehrke"'
Autor:
Michael Jonathan Lehrke, Michael Jeremy Shapiro, Matthew J Rajcula, Madeleine M Kennedy, Shaylene A McCue, Kay L Medina, Virginia Smith Shapiro
Publikováno v:
eLife, Vol 10 (2021)
Iron-sulfur (Fe-S) clusters are cofactors essential for the activity of numerous enzymes including DNA polymerases, helicases, and glycosylases. They are synthesized in the mitochondria as Fe-S intermediates and are exported to the cytoplasm for matu
Externí odkaz:
https://doaj.org/article/b26e13f1acd846d4bac1d67398df6ccb
Autor:
Michael Jeremy Shapiro, Joshua Anderson, Michael Jonathan Lehrke, Meibo Chen, Molly Nelson Holte, Virginia Smith Shapiro
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 7 (2019)
NKAP is a multi-functional nuclear protein that has been shown to be essential for hematopoiesis. Deletion of NKAP in hematopoietic stem cells (HSCs) was previously found to result in rapid lethality and hematopoietic failure. NKAP deficient cells al
Externí odkaz:
https://doaj.org/article/7de0739ec1434095b7b29839cef768b1
Autor:
Madeleine M Kennedy, Kay L. Medina, Michael Jonathan Lehrke, Michael J. Shapiro, Matthew J. Rajcula, Virginia Smith Shapiro, Shaylene A. McCue
Publikováno v:
eLife, Vol 10 (2021)
eLife
eLife
Iron-sulfur (Fe-S) clusters are cofactors essential for the activity of numerous enzymes including DNA polymerases, helicases, and glycosylases. They are synthesized in the mitochondria as Fe-S intermediates and are exported to the cytoplasm for matu
Autor:
Shaylene A. McCue, Matthew J. Rajcula, Michael J. Shapiro, Madeleine M Kennedy, Virginia Smith Shapiro, Kay L. Medina, Michael Jonathan Lehrke
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea20626ae3eface90824cb3165ce487e
https://doi.org/10.7554/elife.69621.sa2
https://doi.org/10.7554/elife.69621.sa2
An irradiated marrow niche reveals a small non-collagenous protein mediator of homing, dermatopontin
Autor:
Alexis Elfstrum, Beau R. Webber, Yuliana Astuti, Athena C Geisness, Troy C. Lund, Justin W. Furcich, Erin E. Nolan, Amanda L. Blake, Jakub Tolar, Michael Jonathan Lehrke, David K. Wood, Ashley C. Kramer, Bruce R. Blazar, Wilaiwan Durose, Mandy E. Taisto
Publikováno v:
Blood Adv
Hematopoietic cell homing after hematopoietic cell transplant (HCT) is governed by several pathways involving marrow niche cells that are evoked after pre-HCT conditioning. To understand the factors that play a role in homing, we performed expression
Autor:
Michael Jonathan Lehrke, Michael J Shapiro, Matthew Rajcula, Keith Theodore, Hyun Se Kim Lee, Virginia Smith Shapiro
Publikováno v:
The Journal of Immunology. 208:107.15-107.15
Iron-sulfur (Fe-S) clusters are cofactors essential for the activity of numerous enzymes including DNA polymerases, helicases, and glycosylases. They are synthesized in the mitochondria as Fe-S intermediates and are exported to the cytoplasm for matu
Autor:
Mandy E. Taisto, Ashley C. Kramer, Troy C. Lund, Beau R. Webber, Michael Jonathan Lehrke, Amanda L. Blake
Publikováno v:
Stem Cell Reports, Vol 9, Iss 3, Pp 770-778 (2017)
Stem cell reports 9(3), 770-778 (2017). doi:10.1016/j.stemcr.2017.07.021
Stem Cell Reports
Stem cell reports 9(3), 770-778 (2017). doi:10.1016/j.stemcr.2017.07.021
Stem Cell Reports
Summary The hematopoietic marrow microenvironment is composed of multiple cell types embedded in an extracellular matrix (ECM). We have explored marrow ECM using mass spectrometry and found dermatopontin (DPT), a small non-collagenous ECM protein, to
Autor:
Virginia Smith Shapiro, Meibo Chen, Michael J. Shapiro, Molly Nelson Holte, Joshua Anderson, Michael Jonathan Lehrke
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 7 (2019)
Frontiers in Cell and Developmental Biology
Frontiers in Cell and Developmental Biology
NKAP is a multi-functional nuclear protein that has been shown to be essential for hematopoiesis. Deletion of NKAP in hematopoietic stem cells (HSCs) was previously found to result in rapid lethality and hematopoietic failure. NKAP deficient cells al
Autor:
Virginia Smith Shapiro, Sinibaldo Romero Arocha, Michael J. Shapiro, Michael Jonathan Lehrke, Ji Young Chung
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 202(8)
NKAP is a multifunctional nuclear protein that associates with the histone deacetylase HDAC3. Although both NKAP and HDAC3 are critical for hematopoietic stem cell (HSC) maintenance and survival, it was not known whether these two proteins work toget
Publikováno v:
ResearcherID
The hematopoietic cell niche serves to maintain hematopoiesis and recruit cells after hematopoietic cell transplant. The determinants of homing and engraftment after transplant are incompletely understood, but are often mediated by small chemokines s