Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Michael John Wright"'
Publikováno v:
Wilkes, J, Scott-tucker, A, Wright, M, Crabbe, T & Scrutton, N 2020, ' Exploiting Single Domain Antibodies as Regulatory Parts to Modulate Monoterpenoid Production in E. coli ', ACS Synthetic Biology, vol. 9, no. 10, pp. 2828-2839 . https://doi.org/10.1021/acssynbio.0c00375
Synthetic biology and metabolic engineering offer potentially green and attractive routes to the production of high value compounds. The provision of high-quality parts and pathways is crucial in enabling the biosynthesis of chemicals using synthetic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::835fe6b4c8fd3a8b8a14ce3df25b379a
https://doi.org/10.1021/acssynbio.0c00375
https://doi.org/10.1021/acssynbio.0c00375
Autor:
Lisa Joedicke, David McMillan, Rebecca J. Burnley, Bernadette Byrne, Marta Westwood, Kaushik Sarkar, Michael John Wright
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Parathyroid hormone receptor 1 (PTH1R) belongs to the secretin class of G protein coupled receptors (GPCRs) and natively binds parathyroid hormone (PTH) and parathyroid hormone related peptide (PTHrP). Ligand binding to PTH1R involves binding to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ab29a5fb6d133f89674926079ef393b
https://pubmed.ncbi.nlm.nih.gov/31594997
https://pubmed.ncbi.nlm.nih.gov/31594997
Autor:
Lindsay K. Shuttleworth, Andrew J. Beavil, Amanda K. F. Oxbrow, Alistair James Henry, Michael W-P Kao, James M. McDonnell, Benjamin P. Cossins, Jean Delgado, Hanna Hailu, Michael John Wright, Nyssa Drinkwater, Brian J. Sutton, Katharine Cain, Anthony H. Keeble
Publikováno v:
Nature structural & molecular biology
Crystallographic and solution studies have shown that IgE molecules are acutely bent in their Fc region. Crystal structures reveal the Cɛ2 domain pair folded back onto the Cɛ3-Cɛ4 domains, but is the molecule exclusively bent or can the Cɛ2 domai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4283914b99886c6d46916dd391611eab
http://europepmc.org/articles/PMC3977038
http://europepmc.org/articles/PMC3977038
Autor:
Andrew J. Beavil, Anthony H. Keeble, Michael John Wright, Alistair James Henry, Ben Cossins, James M. McDonnell, Brian J. Sutton, Nyssa Drinkwater
Publikováno v:
Acta Crystallographica Section A Foundations of Crystallography. 69:s344-s345
Immunoglobulin E (IgE) antibodies mediate allergic reactions, and their binding to FcaRI is responsible for longterm sensitisation of mast cells and basophils [1]. Disruption of this interaction is a validated strategy for therapeutic intervention in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38bd591ed50e3140c307f30fb6280540
https://doi.org/10.1107/s010876731309702x
https://doi.org/10.1107/s010876731309702x