Zobrazeno 1 - 10
of 268
pro vyhledávání: '"Michael J.O. Wakelam"'
Autor:
Gerhard Liebisch, Eoin Fahy, Junken Aoki, Edward A. Dennis, Thierry Durand, Christer S. Ejsing, Maria Fedorova, Ivo Feussner, William J. Griffiths, Harald Köfeler, Alfred H. Merrill, Jr., Robert C. Murphy, Valerie B. O'Donnell, Olga Oskolkova, Shankar Subramaniam, Michael J.O. Wakelam, Friedrich Spener
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 12, Pp 1539-1555 (2020)
A comprehensive and standardized system to report lipid structures analyzed by MS is essential for the communication and storage of lipidomics data. Herein, an update on both the LIPID MAPS classification system and shorthand notation of lipid struct
Externí odkaz:
https://doaj.org/article/2bd36b12c88941a5aed54ffa6bbb5b4e
Autor:
Caroline Gaud, Bebiana C. Sousa, An Nguyen, Maria Fedorova, Zhixu Ni, Valerie B. O’Donnell, Michael J.O. Wakelam, Simon Andrews, Andrea F. Lopez-Clavijo
Publikováno v:
F1000Research, Vol 10 (2021)
Lipidomics increasingly describes the quantification using mass spectrometry of all lipids present in a biological sample. As the power of lipidomics protocols increase, thousands of lipid molecular species from multiple categories can now be profile
Externí odkaz:
https://doaj.org/article/f7e82b5cc00b46379ca16b7b2aaa024d
Autor:
Caroline Gaud, Bebiana C. Sousa, An Nguyen, Maria Fedorova, Zhixu Ni, Valerie B. O’Donnell, Michael J.O. Wakelam, Simon Andrews, Andrea F. Lopez-Clavijo
Publikováno v:
F1000Research, Vol 10 (2021)
Lipidomics increasingly describes the quantitation using mass spectrometry of all lipids present in a biological sample. As the power of lipidomics protocols increase, thousands of lipid molecular species from multiple categories can now be profiled
Externí odkaz:
https://doaj.org/article/9fd5b262d9504d829540cc09c41e0e97
Autor:
Bo Burla, Makoto Arita, Masanori Arita, Anne K. Bendt, Amaury Cazenave-Gassiot, Edward A. Dennis, Kim Ekroos, Xianlin Han, Kazutaka Ikeda, Gerhard Liebisch, Michelle K. Lin, Tze Ping Loh, Peter J. Meikle, Matej Orešič, Oswald Quehenberger, Andrej Shevchenko, Federico Torta, Michael J.O. Wakelam, Craig E. Wheelock, Markus R. Wenk
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 10, Pp 2001-2017 (2018)
Human blood is a self-regenerating lipid-rich biological fluid that is routinely collected in hospital settings. The inventory of lipid molecules found in blood plasma (plasma lipidome) offers insights into individual metabolism and physiology in hea
Externí odkaz:
https://doaj.org/article/d939db0195044f46a836a0fa45ad0636
Autor:
An Nguyen, Anabel Guedán, Aurelie Mousnier, Dawid Swieboda, Qifeng Zhang, Dorottya Horkai, Nicolas Le Novere, Roberto Solari, Michael J.O. Wakelam
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 9, Pp 1671-1684 (2018)
In patients with asthma or chronic obstructive pulmonary disease, rhinovirus (RV) infections can provoke acute worsening of disease, and limited treatment options exist. Viral replication in the host cell induces significant remodeling of intracellul
Externí odkaz:
https://doaj.org/article/adc7376743614064b46060e72123f6b2
Autor:
Simon A. Rudge, Michael J.O. Wakelam
Publikováno v:
Journal of Lipid Research, Vol 57, Iss 2, Pp 176-192 (2016)
Signaling through the phosphoinositide 3-kinase pathways mediates the actions of a plethora of hormones, growth factors, cytokines, and neurotransmitters upon their target cells following receptor occupation. Overactivation of these pathways has been
Externí odkaz:
https://doaj.org/article/db40a123999845ddbc46189c896576b6
Autor:
Karim Bensaad, Elena Favaro, Caroline A. Lewis, Barrie Peck, Simon Lord, Jennifer M. Collins, Katherine E. Pinnick, Simon Wigfield, Francesca M. Buffa, Ji-Liang Li, Qifeng Zhang, Michael J.O. Wakelam, Fredrik Karpe, Almut Schulze, Adrian L. Harris
Publikováno v:
Cell Reports, Vol 9, Iss 1, Pp 349-365 (2014)
Summary: An in vivo model of antiangiogenic therapy allowed us to identify genes upregulated by bevacizumab treatment, including Fatty Acid Binding Protein 3 (FABP3) and FABP7, both of which are involved in fatty acid uptake. In vitro, both were indu
Externí odkaz:
https://doaj.org/article/e1e264078b5c49b6b6c2525e5f12d70f
Autor:
Gerhard Liebisch, Juan Antonio Vizcaíno, Harald Köfeler, Martin Trötzmüller, William J. Griffiths, Gerd Schmitz, Friedrich Spener, Michael J.O. Wakelam
Publikováno v:
Journal of Lipid Research, Vol 54, Iss 6, Pp 1523-1530 (2013)
There is a need for a standardized, practical annotation for structures of lipid species derived from mass spectrometric approaches; i.e., for high-throughput data obtained from instruments operating in either high- or low-resolution modes. This prop
Externí odkaz:
https://doaj.org/article/00981bb9c8694ef0a0e129dabd8693ec
Autor:
Trevor R. Pettitt, Stephen K. Dove, Anneke Lubben, Simon D.J. Calaminus, Michael J.O. Wakelam
Publikováno v:
Journal of Lipid Research, Vol 47, Iss 7, Pp 1588-1596 (2006)
It is now apparent that each of the known, naturally occurring polyphosphoinositides, the phosphatidylinositol monophosphates (PtdIns3P, PtdIns4P, PtdIns5P), phosphatidylinositol bisphosphates [PtdIns(3,4)P2, PtdIns(3,5)P2, PtdIns(4,5)P2], and phosph
Externí odkaz:
https://doaj.org/article/ae5940dc0cc5468abc7a965da7c702bc
Autor:
Eoin Fahy, Shankar Subramaniam, Robert C. Murphy, Masahiro Nishijima, Christian R.H. Raetz, Takao Shimizu, Friedrich Spener, Gerrit van Meer, Michael J.O. Wakelam, Edward A. Dennis
Publikováno v:
Journal of Lipid Research, Vol 50, Iss , Pp S9-S14 (2009)
In 2005, the International Lipid Classification and Nomenclature Committee under the sponsorship of the LIPID MAPS Consortium developed and established a “Comprehensive Classification System for Lipids” based on well-defined chemical and biochemi
Externí odkaz:
https://doaj.org/article/6c25b398bd2a4d3595cc73612685dbbe