Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Michael J.H. Ratcliffe"'
Autor:
Sonja Härtle, Michael J.H. Ratcliffe
Publikováno v:
Avian Immunology ISBN: 9780128187081
Birds have a unique organ for primary B lymphopoiesis, the bursa of Fabricius. Thus, avian B cell development can be classified into pre-bursal, bursal and post-bursal stages. During embryonic development, pre-bursal B cell precursors migrate in a si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1108970ffe313aa63dd6a91bdb522cf3
https://doi.org/10.1016/b978-0-12-818708-1.00019-1
https://doi.org/10.1016/b978-0-12-818708-1.00019-1
Autor:
James S. Adelman, Daniel R. Ardia, Jake Astill, Adam Balic, Paul Barrow, Richard Beal, Andrew G.D. Bean, Cristiano Bortoluzzi, Tina Sørensen Dalgaard, Fred Davison, J.J. (Sjaak) de Wit, Jack C.M. Dekkers, Timothy Doran, Dominique Dunon, Gisela F. Erf, Steven R. Fiddaman, Joel Gautron, Thomas W. Göbel, Rodrigo Guabiraba, Nicolas Guyot, Sonja Härtle, Maxwell Hincke, Thierry Jaffredo, Bernd Kaspers, Jim Kaufman, Michael H. Kogut, Susan J. Lamont, John W. Lowenthal, Katharine E. Magor, Enrique Montiel, Nándor Nagy, Venugopal Nair, Imre Oláh, Claire Powers, Michael J.H. Ratcliffe, Johanna M.J. Rebel, Sophie Réhault-Godbert, Catherine Robin, Karel A. Schat, Ursula Schultz, Benjamin Schusser, Shayan Sharif, Michael A. Skinner, Adrian L. Smith, Kate Sutton, Edwin J.A. Veldhuizen, Lonneke Vervelde, Michal Vinkler, Paul Wigley, Anna Wolc, R. Darren Wood, Laurent Yvernogeau, Huaijun Zhou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4038396693299b0068d8c567526c540e
https://doi.org/10.1016/b978-0-12-818708-1.00002-6
https://doi.org/10.1016/b978-0-12-818708-1.00002-6
Autor:
Michael J.H. Ratcliffe
Avian B cell development is dependent on a specialized organ, the bursa of Fabricius. The embryonic bursa is colonized by limited numbers of B cell precursors that subsequently develop within the bursa and emigrate to generate a population of periphe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69566dbe7b3fe598ad4e2fe5613faf7b
https://doi.org/10.1016/b978-0-12-374279-7.01018-3
https://doi.org/10.1016/b978-0-12-374279-7.01018-3
Autor:
Michael J.H. Ratcliffe
Publikováno v:
Developmental & Comparative Immunology. 30:101-118
The bursa of Fabricius is critical for the normal development of B lymphocytes in birds. It is productively colonized during embryonic life by a limited number of B cell precursors that have undergone the immunoglobulin gene rearrangements required f
Autor:
Michael J.H. Ratcliffe, Kelly A. Pike
Publikováno v:
The Journal of Immunology. 174:2012-2020
Surface Ig (sIg) expression is a critical checkpoint during avian B cell development. Only cells that express sIg colonize bursal follicles, clonally expand, and undergo Ig diversification by gene conversion. Expression of a heterodimer, in which the
Publikováno v:
The Journal of Immunology. 172:2210-2218
The B cell receptor complex (BcR) is essential for normal B lymphocyte function, and surface BcR expression is a crucial checkpoint in B cell development. However, functional requirements for chains of the BcR during development remain controversial.
Autor:
Michael J.H. Ratcliffe, Kelly A. Pike
Publikováno v:
Seminars in Immunology. 14:351-358
Expression of surface immunoglobulin (sIg) related receptors has been conserved in phylogenetically distinct species as a critical checkpoint in B cell development. The sIg receptor comprises extracellular IgM heavy and light chains, with the potenti
Autor:
James S. Adelman, Daniel R. Ardia, Paul Barrow, Richard Beal, Fred Davison, Jack C.M. Dekkers, Mary Delany, Dominique Dunon, Gisela F. Erf, Julien S. Fellah, Thomas W. Göbel, Sonja Härtle, Thierry Jaffredo, Helle R. Juul-Madsen, Pete Kaiser, Bernd Kaspers, Jim Kaufman, Kirk C. Klasing, Elizabeth A. Koutsos, Susan J. Lamont, Blanca Lupiani, Katherine E. Magor, Nándor Nagy, Venugopal Nair, Tom O’Hare, Imre Oláh, Claire Powers, Michael J.H. Ratcliffe, Sanjay M. Reddy, Karel A. Schat, Virgil Schijns, Ursula Schultz, Michael A. Skinner, Adrian L. Smith, Peter Stäheli, Saskia van de Zande, Lonneke Vervelde, Birgit Viertlböeck, Paul Wigley, Huaijun Zhou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f3d930a2b0f7b63a8884b37bb5653abd
https://doi.org/10.1016/b978-0-12-396965-1.00028-5
https://doi.org/10.1016/b978-0-12-396965-1.00028-5
Autor:
Michael J.H. Ratcliffe, Kelly A. Pike, Camil E. Sayegh, Jennifer E. Friedman, Sandra L. Demaries
Publikováno v:
Immunological Reviews. 175:187-200
The bursa of Fabricius is critical to normal B-lymphocyte development in birds. During embryonic life, B-cell precursors migrate to the bursal rudiment and those which have undergone productive V(D)J recombination colonize lymphoid follicles and unde