Zobrazeno 1 - 10
of 145
pro vyhledávání: '"Michael J. Zuscik"'
Autor:
Sara E. Buckley DO, Mary C. Hamati MD, Michael A. Hewitt BA, Cheryl L. Ackert-Bicknell PhD, Michael J. Zuscik PhD, Joshua A. Metzl MD, Daniel K. Moon MD, MS, MBA, Kenneth J. Hunt MD
Publikováno v:
Foot & Ankle Orthopaedics, Vol 7 (2022)
Category: Ankle Arthritis; Arthroscopy; Basic Sciences/Biologics; Trauma Introduction/Purpose: Post-traumatic Osteoarthritis (OA) of the ankle is a debilitating condition that impacts millions of people. However, little is known about the genetic and
Externí odkaz:
https://doaj.org/article/a5b1ce6d5bbb4fb9baa3b5d2ecf54af3
Autor:
Mary C. Hamati MD, Robert Maynard, Jonathan Bartolomei MS, Michael J. Zuscik PhD, Cheryl L. Ackert-Bicknell PhD, Kenneth J. Hunt MD
Publikováno v:
Foot & Ankle Orthopaedics, Vol 7 (2022)
Category: Ankle; Ankle Arthritis; Basic Sciences/Biologics; Trauma Introduction/Purpose: Osteoarthritis (OA) of the lower limb is a debilitating, incurable, expensive and prevalent condition in people over 45. Although ankle posttraumatic OA (PTOA) h
Externí odkaz:
https://doaj.org/article/ead4f067bfd5406b96cc8da8d493df7a
Autor:
Samantha H. Landgrave, Toru Ishii, Robert Maynard, Andrew Wu, Dana Godfrey, Terrin Manes, Veronica Butler, David Villani, Honey Hendesi, Rachel Frank, Srividhya Iyer, Karin Payne, Douglas J. Adams, Lacey Favazzo, Beate Lanske, Michael J. Zuscik
Publikováno v:
Journal of Clinical and Translational Science, Vol 6, Pp 53-53 (2022)
OBJECTIVES/GOALS: Osteoarthritis (OA) is a cartilage destroying disease. We are investigating abaloparatide (ABL) activation of parathyroid hormone receptor type 1 (PTH1R), which is expressed by articular chondrocytes in OA. We propose ABL treatment
Externí odkaz:
https://doaj.org/article/eae651ba28a74f96a5f4c54514534c22
Publikováno v:
Current Osteoporosis Reports. 20:141-152
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d0b155ba457ef86e14c9cbbdbae144ae
https://doi.org/10.1007/s11914-022-00726-x
https://doi.org/10.1007/s11914-022-00726-x
Autor:
Qurratul-Ain Dar, Eric M Schott, Sarah E Catheline, Robert D Maynard, Zhaoyang Liu, Fadia Kamal, Christopher W Farnsworth, John P Ketz, Robert A Mooney, Matthew J Hilton, Jennifer H Jonason, Janne Prawitt, Michael J Zuscik
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0174705 (2017)
Osteoarthritis (OA) is a degenerative joint disease for which there are no disease modifying therapies. Thus, strategies that offer chondroprotective or regenerative capability represent a critical unmet need. Recently, oral consumption of a hydrolyz
Externí odkaz:
https://doaj.org/article/ec104c274e734809af1fa423b08845bc
Autor:
Honey Hendesi, Eric M. Schott, Michael J. Zuscik, Qurratul-Ain Dar, Lacey J. Favazzo, Sarah Soniwala, David A. Villani, Steven R. Gill
Publikováno v:
Current Opinion in Rheumatology
Supplemental Digital Content is available in the text
Purpose of review Osteoarthritis is a debilitating disease leading to joint degeneration, inflammation, pain, and disability. Despite efforts to develop a disease modifying treatment, the onl
Purpose of review Osteoarthritis is a debilitating disease leading to joint degeneration, inflammation, pain, and disability. Despite efforts to develop a disease modifying treatment, the onl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a0a1e800a8818f0c6b1e7e03c6b251c
https://doi.org/10.1097/bor.0000000000000681
https://doi.org/10.1097/bor.0000000000000681
Autor:
Armaghan Mahmoudian, Ursule Kalvaityte, Lacey J. Favazzo, Cyro Scala de Almeida, Michael J. Zuscik, Stan Kubow, Ali Mobasheri, Christina E. Larder, Pieter J. Emans, Perola Grimberg Plapler, Michèle M. Iskandar, Paulo Cesar Hamdan, Luc J. C. van Loon, Ilona Uzieliene
Publikováno v:
Current Rheumatology Reports, 23(11):78. Springer, Cham
Current Rheumatology Reports
Current Rheumatology Reports
Purpose of Review Osteoarthritis (OA) is the most common forms of arthritis in the general population, accounting for more pain and functional disability than any other musculoskeletal disease. There are currently no approved disease modifying drugs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::295d22a9d9cd697f039175b18eafe3ec
https://doi.org/10.1007/s11926-021-01042-6
https://doi.org/10.1007/s11926-021-01042-6
Autor:
Christopher Dean, Brendan F. Boyce, M. Nick James, Martin Chang, Michael J. Zuscik, John P. Ketz, Elizabeth Botto, Katherine Escalera-Rivera, Richard D. Bell, Luke S. Oluoch, Sarah E. Catheline, Jennifer H. Jonason, Robert D. Maynard
Publikováno v:
Science signaling. 14(701)
Canonical nuclear factor κB (NF-κB) signaling mediated by homo- and heterodimers of the NF-κB subunits p65 (RELA) and p50 (NFKB1) is associated with age-related pathologies and with disease progression in posttraumatic models of osteoarthritis (OA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7bf996e28e6e2081c7203bacbe63c37
https://pubmed.ncbi.nlm.nih.gov/35380880
https://pubmed.ncbi.nlm.nih.gov/35380880
Autor:
Michael A David, Khyrie H Jones, Jason A Inzana, Michael J Zuscik, Hani A Awad, Robert A Mooney
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e91234 (2014)
The obesity epidemic has resulted in a large increase in type 2 diabetes (T2D). While some secondary complications of T2D are well recognized and their cellular and molecular mechanisms are defined, the impact of T2D on the musculoskeletal system is
Externí odkaz:
https://doaj.org/article/8e7ffadeede24d7497209fbdd86ec413
Autor:
Guoyong Yin, Tzong-Jen Sheu, Prashanthi Menon, Jinjiang Pang, Hsin-Chiu Ho, Shanshan Shi, Chao Xie, Elaine Smolock, Chen Yan, Michael J Zuscik, Bradford C Berk
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e89127 (2014)
G protein coupled receptor kinase 2 (GRK2) interacting protein-1 (GIT1), is a scaffold protein that plays an important role in angiogenesis and osteoclast activity. We have previously demonstrated that GIT1 knockout (GIT1 KO) mice have impaired angio
Externí odkaz:
https://doaj.org/article/28e2069476784fb389f85b2440fa3535