Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Michael J. Wester"'
Autor:
Mohamadreza Fazel, Michael J. Wester, David J. Schodt, Sebastian Restrepo Cruz, Sebastian Strauss, Florian Schueder, Thomas Schlichthaerle, Jennifer M. Gillette, Diane S. Lidke, Bernd Rieger, Ralf Jungmann, Keith A. Lidke
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Single-molecule localization microscopy relies on stochastic blinking events, treated as independent events without assignment to a particular emitter. Here, BaGoL takes low precision localizations generated from multiple emitter blinkings during DNA
Externí odkaz:
https://doaj.org/article/337d012c98924a5584c57b0dfa7a0f77
Autor:
Michael J. Wester, David J. Schodt, Hanieh Mazloom-Farsibaf, Mohamadreza Fazel, Sandeep Pallikkuth, Keith A. Lidke
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract We describe a robust, fiducial-free method of drift correction for use in single molecule localization-based super-resolution methods. The method combines periodic 3D registration of the sample using brightfield images with a fast post-proce
Externí odkaz:
https://doaj.org/article/475849048ed14e0398cdd277211aaefd
Autor:
Mohamadreza Fazel, Michael J. Wester
Publikováno v:
AIP Advances, Vol 12, Iss 1, Pp 010701-010701-29 (2022)
The diffraction of light imposes a fundamental limit on the resolution of light microscopes. This limit can be circumvented by creating and exploiting independent behaviors of the sample at length scales below the diffraction limit. In super-resoluti
Externí odkaz:
https://doaj.org/article/9232c61d3fb94cf88ead9e3f77e7e53e
Publikováno v:
Bioinformatics and Biology Insights, Vol 16 (2022)
We previously developed a method of defining receptor clusters in the membrane based on mutual distance and applied it to a set of transmission microscopy images of vascular endothelial growth factor receptors. An optimal length parameter was identif
Externí odkaz:
https://doaj.org/article/3f05bf47d0d04dd8bf04330e8cab2229
Autor:
Simone C. Oostindie, Derek A. Rinaldi, Gijs G. Zom, Michael J. Wester, Desiree Paulet, Kusai Al-Tamimi, Els van der Meijden, Jennifer R. Scheick, Tessa Wilpshaar, Bart de Jong, Marloes Hoff-van den Broek, Rachel M. Grattan, Janita J. Oosterhoff, Julie Vignau, Sandra Verploegen, Peter Boross, Frank J. Beurskens, Diane S. Lidke, Janine Schuurman, Rob N. de Jong
Publikováno v:
Nature Biotechnology. 40:1509-1519
The use of therapeutic monoclonal antibodies is constrained because single antigen targets often do not provide sufficient selectivity to distinguish diseased from healthy tissues. We present HexElect®, an approach to enhance the functional selectiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::37adbdc10c2c7fdd110d991a2ca6fa2f
https://doi.org/10.1038/s41587-022-01384-1
https://doi.org/10.1038/s41587-022-01384-1
Autor:
Michael J. Wester
Publikováno v:
Mathematics in Computer Science. 16
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b83f418ab6b7208a9a1127ce70f6e54e
https://doi.org/10.1007/s11786-022-00541-8
https://doi.org/10.1007/s11786-022-00541-8
Autor:
Diane S. Lidke, Keith A. Lidke, Julian A. Rojo, David J. Schodt, Michael J. Wester, Rachel M. Grattan, Emanuel Salazar-Cavazos, Elizabeth M. Bailey
Publikováno v:
J Vis Exp
Phosphorylation is a necessary posttranslational modification that regulates protein function and directs cell signaling outcomes. Current methods to measure protein phosphorylation cannot preserve the heterogeneity in phosphorylation across individu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b92900651dda7c657ae070a1a454ebb
https://doi.org/10.3791/63665-v
https://doi.org/10.3791/63665-v
Autor:
David Schodt, Michael J. Wester, Mohamadreza Fazel, Hanieh Mazloom-Farsibaf, Sandeep Pallikkuth, Sajjad A. Khan, Marjolein B.M. Meddens, Farzin Farzam, William K. Kanagy, Derek A. Rinaldi, Elton D. Jhamba, Keith A. Lidke
Publikováno v:
Biophysical Journal. 122:275a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f24f27e2d7e89085813e79615787b92a
https://doi.org/10.1016/j.bpj.2022.11.1568
https://doi.org/10.1016/j.bpj.2022.11.1568
Autor:
Matthew S Graus, Carolyn Pehlke, Michael J Wester, Lisa B Davidson, Stanly L Steinberg, Aaron K Neumann
Publikováno v:
PLoS Computational Biology, Vol 10, Iss 5, p e1003639 (2014)
To understand the process of innate immune fungal recognition, we developed computational tools for the rigorous quantification and comparison of receptor recruitment and distribution at cell-cell contact sites. We used these tools to quantify patter
Externí odkaz:
https://doaj.org/article/263374a4f4324948a34b06a4e2caeeef
Autor:
Simone C, Oostindie, Derek A, Rinaldi, Gijs G, Zom, Michael J, Wester, Desiree, Paulet, Kusai, Al-Tamimi, Els, van der Meijden, Jennifer R, Scheick, Tessa, Wilpshaar, Bart, de Jong, Marloes, Hoff-van den Broek, Rachel M, Grattan, Janita J, Oosterhoff, Julie, Vignau, Sandra, Verploegen, Peter, Boross, Frank J, Beurskens, Diane S, Lidke, Janine, Schuurman, Rob N, de Jong
Publikováno v:
Nature biotechnology. 40(10)
The use of therapeutic monoclonal antibodies is constrained because single antigen targets often do not provide sufficient selectivity to distinguish diseased from healthy tissues. We present HexElect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2f9d47a2d156096e415c018ab095c482
https://pubmed.ncbi.nlm.nih.gov/35879363
https://pubmed.ncbi.nlm.nih.gov/35879363