Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Michael J. W. Johnston"'
Autor:
Wanyue Zhang, Angela Sloan, Jérémie Prévost, Levi Tamming, Sathya Raman, Annabelle Pfeifle, Caroline Gravel, Wangxue Chen, Anwar M. Hashem, Jianguo Wu, Jingxin Cao, Michael J. W. Johnston, Lisheng Wang, Simon Sauve, Michael Rosu-Myles, Darwyn Kobasa, David Safronetz, Xuguang Li
Publikováno v:
Emerging Microbes and Infections, Vol 13, Iss 1 (2024)
The nucleoprotein (NP) of type A influenza virus (IAV) is highly conserved across all virus strains, making it an attractive candidate antigen for universal vaccines. While various studies have explored NP-induced mucosal immunity, here we interrogat
Externí odkaz:
https://doaj.org/article/af91b9f97e864ad2ba7ba06b0cb566c9
Autor:
Annabelle Pfeifle, Wanyue Zhang, Jingxin Cao, Sathya N. Thulasi Raman, Rose Anderson-Duvall, Levi Tamming, Caroline Gravel, Heather Coatsworth, Wangxue Chen, Michael J. W. Johnston, Simon Sauve, Michael Rosu-Myles, Lisheng Wang, Xuguang Li
Publikováno v:
Emerging Microbes and Infections, Vol 13, Iss 1 (2024)
The rising prevalence of Lyme disease (LD) in North America and Europe has emerged as a pressing public health concern. Despite the availability of veterinary LD vaccines, no vaccine is currently available for human use. Outer surface protein C (OspC
Externí odkaz:
https://doaj.org/article/837dc5a0535f48e28585ad366021997c
Autor:
Annabelle Pfeifle, Sathya N. Thulasi Raman, Casey Lansdell, Wanyue Zhang, Levi Tamming, Jonathon Cecillon, Emmanuel Laryea, Devina Patel, Jianguo Wu, Caroline Gravel, Grant Frahm, Jun Gao, Wangxue Chen, George Chaconas, Simon Sauve, Michael Rosu-Myles, Lisheng Wang, Michael J. W. Johnston, Xuguang Li
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionThe incidence of Lyme disease (LD) in Canada and the United States has risen over the last decade, nearing 480,000 cases each year. Borrelia burgdorferi sensu lato, the causative agent of LD, is transmitted to humans through the bite of a
Externí odkaz:
https://doaj.org/article/f0e5aaec002d4d639fc98c48521fb471
Autor:
Wanyue Zhang, Annabelle Pfeifle, Casey Lansdell, Grant Frahm, Jonathon Cecillon, Levi Tamming, Caroline Gravel, Jun Gao, Sathya N. Thulasi Raman, Lisheng Wang, Simon Sauve, Michael Rosu-Myles, Xuguang Li, Michael J. W. Johnston
Publikováno v:
Vaccines, Vol 11, Iss 10, p 1580 (2023)
In recent years, lipid nanoparticles (LNPs) have emerged as a revolutionary technology for vaccine delivery. LNPs serve as an integral component of mRNA vaccines by protecting and transporting the mRNA payload into host cells. Despite their prominenc
Externí odkaz:
https://doaj.org/article/747e2768207344e39af4cad79c47ad35
Autor:
Donald Gagné, Muzaddid Sarker, Geneviève Gingras, Derek J. Hodgson, Grant Frahm, Marybeth Creskey, Barry Lorbetskie, Stewart Bigelow, Jun Wang, Xu Zhang, Michael J. W. Johnston, Huixin Lu, Yves Aubin
Publikováno v:
PLoS ONE, Vol 18, Iss 11 (2023)
Externí odkaz:
https://doaj.org/article/32224d54ec3e4446af9f4b89766281d7
Autor:
Jonathan Gobin, Gauri Muradia, Jelica Mehic, Carole Westwood, Lauren Couvrette, Andrew Stalker, Stewart Bigelow, Christian C. Luebbert, Frédéric St-Denis Bissonnette, Michael J. W. Johnston, Simon Sauvé, Roger Y. Tam, Lisheng Wang, Michael Rosu-Myles, Jessie R. Lavoie
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-20 (2021)
Abstract Background Extracellular vesicles (EVs) produced by human bone marrow-derived mesenchymal stromal cells (hBM-MSCs) are currently investigated for their clinical effectiveness towards immune-mediated diseases. The large amounts of stem cell-d
Externí odkaz:
https://doaj.org/article/a55f2bdc68d84265a2f18242fd0f7540
Autor:
Christian C. E. Luebbert, Rola Mansa, Raisa Rahman, Zygmunt J. Jakubek, Grant E. Frahm, Shan Zou, Michael J. W. Johnston
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract The development of reference standards for nanoparticle sizing allows for cross laboratory studies and effective transfer of particle sizing methodology. To facilitate this, these reference standards must be stable upon long-term storage. He
Externí odkaz:
https://doaj.org/article/a70c2e3ff8ec46fc836e709e22829d94
Publikováno v:
ACS Omega, Vol 5, Iss 49, Pp 31845-31857 (2020)
Externí odkaz:
https://doaj.org/article/c9c43f50521a441083364e0565e1ce04
Autor:
Levi A. Tamming, Diana Duque, Anh Tran, Wanyue Zhang, Annabelle Pfeifle, Emmanuel Laryea, Jianguo Wu, Sathya N. Thulasi Raman, Caroline Gravel, Marsha S. Russell, Anwar M. Hashem, Reem M. Alsulaiman, Rowa Y. Alhabbab, Jun Gao, David Safronetz, Jingxin Cao, Lisheng Wang, Wangxue Chen, Michael J. W. Johnston, Simon Sauve, Michael Rosu-Myles, Xuguang Li
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
SARS-CoV-2 infections present a tremendous threat to public health. Safe and efficacious vaccines are the most effective means in preventing the infections. A variety of vaccines have demonstrated excellent efficacy and safety around the globe. Yet,
Externí odkaz:
https://doaj.org/article/f49d60fb6e59440786746454cf911d6b
Autor:
Afnan Munshi, Jelica Mehic, Marybeth Creskey, Jonathan Gobin, Jun Gao, Emma Rigg, Gauri Muradia, Christian C. Luebbert, Carole Westwood, Andrew Stalker, David S. Allan, Michael J. W. Johnston, Terry Cyr, Michael Rosu-Myles, Jessie R. Lavoie
Publikováno v:
Stem Cell Research & Therapy, Vol 10, Iss 1, Pp 1-18 (2019)
Abstract Background Clinical applications have shown extracellular vesicles (EVs) to be a major paracrine effector in therapeutic responses produced by human mesenchymal stromal/stem cells (hMSCs). As the regenerative capacity of EVs is mainly ascrib
Externí odkaz:
https://doaj.org/article/699ae8e7d7ea4864b8c63797fe386e89