Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Michael J. V. da Silva"'
Autor:
Julia Poletto, Michael J. V. da Silva, Karlos E. Pianoski, Julia C. M. Willig, Fernanda A. Rosa
Publikováno v:
The Journal of Organic Chemistry. 87:8544-8550
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc9613807a4eb936078acfc1032d6b7b
https://doi.org/10.1021/acs.joc.2c00657
https://doi.org/10.1021/acs.joc.2c00657
Autor:
Mariellen Guilherme dos Santos, Celso Vataru Nakamura, Karlos Eduardo Pianoski, Julia Poletto, Samara Mendes de Souza Melo, Sidnei Moura, Michael J. V. da Silva, Danielle Lazarin-Bidóia, Fernanda A. Rosa, Hélito Volpato
Publikováno v:
ChemistryOpen
ChemistryOpen, Vol 10, Iss 10, Pp 931-938 (2021)
ChemistryOpen, Vol 10, Iss 10, Pp 930-930 (2021)
ChemistryOpen, Vol 10, Iss 10, Pp 931-938 (2021)
ChemistryOpen, Vol 10, Iss 10, Pp 930-930 (2021)
A series of 60 4‐aminomethyl 5‐aryl‐3‐substituted isoxazoles were synthesized by an efficient method and evaluated in vitro against Leishmania amazonensis and Trypanosoma cruzi, protozoa that cause the neglected tropical diseases leishmaniasi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ce4f683984e743c29b1ecad2e5fee68
https://doi.org/10.1002/open.202100141
https://doi.org/10.1002/open.202100141
Autor:
Julia, Poletto, Michael J V, da Silva, Karlos E, Pianoski, Julia C M, Willig, Fernanda A, Rosa
Publikováno v:
The Journal of organic chemistry. 87(13)
A simple, efficient and highly regioselective method for the preparation of 3,4- and 4,5-disubstituted
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b6b7f0245531e861990114f33ac998c4
https://pubmed.ncbi.nlm.nih.gov/35687873
https://pubmed.ncbi.nlm.nih.gov/35687873
Autor:
Danielle Lazarin Bidóia, Celso Vataru Nakamura, Julia Poletto, Michael J. V. da Silva, Andrey P. Jacomini, Fernanda A. Rosa, Hélito Volpato
Publikováno v:
Drug Development Research. 82:230-240
In this article, a series of 29 new pyrimidine N-acylhydrazone hybrids were synthesized and evaluated in vitro against Leishmania amazonensis and Trypanosoma cruzi protozoa that cause the neglected diseases cutaneous leishmaniasis and Chagas disease,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c3fd1439fd02e38ba38fc6ef1f61aa9
https://doi.org/10.1002/ddr.21745
https://doi.org/10.1002/ddr.21745
Autor:
Sidnei Moura, Fernanda A. Rosa, Julia Poletto, Michael J. V. da Silva, Davi F. Back, Andrey P. Jacomini, Gessica M. Ribeiro, Ernani A. Basso
Publikováno v:
Organic Letters. 21:6325-6328
An efficient one-pot method is described for the highly regioselective synthesis of α-ketoamide N-arylpyrazoles from secondary β-enamino diketones. For this, the key intermediate, 4-acyl 3,5-dihydroxypyrrolone, was generated in situ and underwent b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c0b2cf793ecc1ab3aba983302dce298
https://doi.org/10.1021/acs.orglett.9b02206
https://doi.org/10.1021/acs.orglett.9b02206
Autor:
Mary Ann Foglio, Fávero Reisdorfer Paula, Fernanda A. Rosa, Ana Lúcia Tasca Gois Ruiz, Mariana Cecchetto Figueiredo, Michael J. V. da Silva, Davi F. Back, Andrey P. Jacomini
Publikováno v:
Bioorganicmedicinal chemistry. 29
A new one-pot two-step sequential methodology for synthesis of novel 3-carboxyethyl 4-[(tert-butylamino)methyl]-N-arylpyrazole derivatives is reported. One-pot transformation of β-enamino diketones and arylhydrazines generated 4-iminium-N-arylpyrazo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50c7c7f644a707fb63cfd7e3e3c2c576
https://pubmed.ncbi.nlm.nih.gov/33214037
https://pubmed.ncbi.nlm.nih.gov/33214037
Autor:
Jeniffer do Nascimento Ascencio Camargo, Julia Poletto, Fernanda A. Rosa, Karlos Eduardo Pianoski, Michael J. V. da Silva, Andrey P. Jacomini, Sidnei Moura, Davi F. Back, Davana S. Gonçalves
Publikováno v:
Organicbiomolecular chemistry. 18(13)
A simple and efficient methodology for highly regioselective synthesis of azomethine pyrazoles and isoxazoles containing a trifluoromethyl group is reported. The cyclocondensation of trifluoromethylated β-enamino diketones (TBED) with phenylhydrazin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ce5a041e7a596e546556543eadc735f
https://pubmed.ncbi.nlm.nih.gov/32196053
https://pubmed.ncbi.nlm.nih.gov/32196053
Autor:
Danielle Lazarin Bidóia, Karlos Eduardo Pianoski, Alisson Felipe Oliveira, Samara Mendes de Souza Melo, Davana S. Gonçalves, Franciele Queiroz Ames, Fávero Reisdorfer Paula, Fernanda A. Rosa, Hélito Volpato, Rafael Pazinatto Aguiar, Celso Vataru Nakamura, Sidnei Moura, Davi F. Back, Ciomar Aparecida Bersani-Amado, Michael J. V. da Silva, Andrey P. Jacomini
Publikováno v:
Bioorganicmedicinal chemistry. 28(12)
The inflammatory response is the reaction of living tissue to an injury of a foreign nature, such as infection and irritants, and occurs as part of the body's natural defence response. Compounds capable of inhibiting cyclooxygenase (COX) enzymes, esp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50fb7da13e57a6d35d44451bbcb2a906
https://pubmed.ncbi.nlm.nih.gov/32503692
https://pubmed.ncbi.nlm.nih.gov/32503692
Autor:
Karlos Eduardo Pianoski, Michael J. V. da Silva, Mariellen Guilherme dos Santos, Julia Poletto, Samara Mendes de Souza Melo, Sidnei Moura, Danielle Lazarin-Bidóia, Fernanda A. Rosa, Hélito Volpato, Celso Vataru Nakamura
Publikováno v:
ChemistryOpen
The Front Cover shows the contribution of the SINTHET research group to the synthesis and discovery of new antiprotozoal compounds. The synthetic methodology allowed 60 new diversified isoxazole derivatives with structural variations on the 3‐, 4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e95531e840c08839319938e5479e1fa3
https://doi.org/10.1002/open.202100214
https://doi.org/10.1002/open.202100214