Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Michael J. V. White"'
Autor:
Michael J. V. White, Melis Ozkan, Jorge Emiliano Gomez-Medellin, Michal M. Rączy, Kyle M. Koss, Ani Solanki, Zheng Jenny Zhang, Aaron T. Alpar, Bilal A. Naved, Jason Wertheim, Jeffrey A. Hubbell
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-19 (2024)
Abstract Fibrosis is involved in 45% of deaths in the United States, and no treatment exists to reverse the progression of lung or kidney fibrosis. Myofibroblasts are key to the progression and maintenance of fibrosis. We investigated features of cel
Externí odkaz:
https://doaj.org/article/f97277bb22ed485abe8d738c965ae2af
Publikováno v:
npj Regenerative Medicine, Vol 7, Iss 1, Pp 1-11 (2022)
Abstract The biomaterial fibrin is widely used as a clinical tissue sealant in surgery. In preclinical research, fibrin is also extensively studied as a carrier material for growth factor delivery. In these applications, premature fibrin degradation
Externí odkaz:
https://doaj.org/article/735cb2120e384debbb2fc2348f4495cc
Publikováno v:
npj Regenerative Medicine, Vol 6, Iss 1, Pp 1-12 (2021)
Abstract Chronic non-healing wounds, frequently caused by diabetes, lead to lower quality of life, infection, and amputation. These wounds have limited treatment options. We have previously engineered growth factors to bind to exposed extracellular m
Externí odkaz:
https://doaj.org/article/c930dc77d1ca49068331a5f7d4510f03
Autor:
Jun Ishihara, Ako Ishihara, Kazuto Fukunaga, Koichi Sasaki, Michael J. V. White, Priscilla S. Briquez, Jeffrey A. Hubbell
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Laminins are important regulators of epidermal wound healing. Here, the authors show that laminins bind to multiple growth factors via their heparin-binding domains, and that incorporation of these domains into fibrin matrices increases growth factor
Externí odkaz:
https://doaj.org/article/970479756e7a4accbe4500ad2b9305a7
Autor:
Michael J V White, Richard H Gomer
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0138748 (2015)
For both wound healing and the formation of a fibrotic lesion, circulating monocytes enter the tissue and differentiate into fibroblast-like cells called fibrocytes and pro-fibrotic M2a macrophages, which together with fibroblasts form scar tissue. M
Externí odkaz:
https://doaj.org/article/11c7612dfa2547458b27fdf4bc412186
Autor:
Michael Laffan, Koval E. Smith, Koichi Sasaki, Jun Ishihara, Matthias P. Lutolf, Jeffrey A. Hubbell, Michael J. V. White, Yoji Tabata, Kazuto Fukunaga, Richard D. Starke, Thomas A. J. McKinnon, Ako Ishihara, Claire Peghaire, Anna M. Randi
Publikováno v:
Blood. 133:2559-2569
During wound healing, the distribution, availability, and signaling of growth factors (GFs) are orchestrated by their binding to extracellular matrix components in the wound microenvironment. Extracellular matrix proteins have been shown to modulate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd28d846b14428547fd5c68c2070992e
https://doi.org/10.1182/blood.2019000510
https://doi.org/10.1182/blood.2019000510
Autor:
Michael J. V. White
Publikováno v:
Australian Journal of Human Rights. 25:44-65
New Zealand was an early adopter of the Optional Protocol to the Convention Against Torture (OPCAT) and its unique preventive approach. It is now over 10 years since New Zealand established its mul...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a83629abe6c65fef02de7cefa3d35c6
https://doi.org/10.1080/1323238x.2019.1588055
https://doi.org/10.1080/1323238x.2019.1588055
Autor:
Michael J. V. White
Publikováno v:
Business and Human Rights in Asia ISBN: 9789811572722
There is a growing momentum globally around National Action Plans (NAPs) for the implementation of the UN Guiding Principles on Business and Human Rights (UNGPs). Traditionally, NAPs provide a way for governments to set out their expectations of busi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c29ae03590e5c7214caa67e2433dccac
https://doi.org/10.1007/978-981-15-7273-9_2
https://doi.org/10.1007/978-981-15-7273-9_2
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e70795 (2013)
Trypsin-containing topical treatments can be used to speed wound healing, although the mechanism of action is unknown. To help form granulation tissue and heal wounds, monocytes leave the circulation, enter the wound tissue, and differentiate into fi
Externí odkaz:
https://doaj.org/article/fd298c6f84ba47079aa3659500f1095d
Autor:
Michael J. V. White
Publikováno v:
National Human Rights Institutions in Southeast Asia ISBN: 9789811510731
National Human Rights Institutions (NHRIs) are one of the most important institutional developments of recent years. NHRIs can play a key role in promoting and protecting human rights. They are able to do so by the unique position they occupy between
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d43edc75e1bd88b1acbb175cbff324fb
https://doi.org/10.1007/978-981-15-1074-8_2
https://doi.org/10.1007/978-981-15-1074-8_2