Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Michael J. Texada"'
Autor:
Olga Kubrak, Anne F. Jørgensen, Takashi Koyama, Mette Lassen, Stanislav Nagy, Jacob Hald, Gianluca Mazzoni, Dennis Madsen, Jacob B. Hansen, Martin Røssel Larsen, Michael J. Texada, Jakob L. Hansen, Kenneth V. Halberg, Kim Rewitz
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-22 (2024)
Abstract Obesity impairs tissue insulin sensitivity and signaling, promoting type-2 diabetes. Although improving insulin signaling is key to reversing diabetes, the multi-organ mechanisms regulating this process are poorly defined. Here, we screen th
Externí odkaz:
https://doaj.org/article/c0b57de7e927476fa4302bfb4b15a306
Autor:
Olga Kubrak, Takashi Koyama, Nadja Ahrentløv, Line Jensen, Alina Malita, Muhammad T. Naseem, Mette Lassen, Stanislav Nagy, Michael J. Texada, Kenneth V. Halberg, Kim Rewitz
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Intestinal nutrient-sensing is important in metabolic control. Here the authors show that the gut-derived hormone Allatostatin C, a somatostatin homolog in fruit flies, links enteric nutrient sensing to behavioral and metabolic adaptations that maint
Externí odkaz:
https://doaj.org/article/e034d13ae63b4246ba92550680fc92f3
Autor:
Michael J. Texada, Anne F. Jørgensen, Christian F. Christensen, Takashi Koyama, Alina Malita, Daniel K. Smith, Dylan F. M. Marple, E. Thomas Danielsen, Sine K. Petersen, Jakob L. Hansen, Kenneth A. Halberg, Kim F. Rewitz
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
The mechanisms by which organisms adapt their growth according to the availability of oxygen are incompletely understood. Here the authors identify the D rosophila fat body as a tissue regulating growth in response to oxygen sensing via a mechanism i
Externí odkaz:
https://doaj.org/article/eb1d36697d6243149fc5a3d90944c202
Autor:
Gianna W Maurer, Alina Malita, Stanislav Nagy, Takashi Koyama, Thomas M Werge, Kenneth A Halberg, Michael J Texada, Kim Rewitz
Publikováno v:
PLoS Genetics, Vol 16, Iss 4, p e1008727 (2020)
The human 22q11.2 chromosomal deletion is one of the strongest identified genetic risk factors for schizophrenia. Although the deletion spans a number of known genes, the contribution of each of these to the 22q11.2 deletion syndrome (DS) is not know
Externí odkaz:
https://doaj.org/article/754103e1b0a3419a81ae0cc614f92f0f
Autor:
Meet Zandawala, Maria E Yurgel, Michael J Texada, Sifang Liao, Kim F Rewitz, Alex C Keene, Dick R Nässel
Publikováno v:
PLoS Genetics, Vol 14, Iss 11, p e1007767 (2018)
Behavior and physiology are orchestrated by neuropeptides acting as central neuromodulators and circulating hormones. An outstanding question is how these neuropeptides function to coordinate complex and competing behaviors. In Drosophila, the neurop
Externí odkaz:
https://doaj.org/article/824b4282647f4f9fa0cb6b446bfb8b18
Autor:
Tomotsune Ameku, Yuto Yoshinari, Michael J Texada, Shu Kondo, Kotaro Amezawa, Goro Yoshizaki, Yuko Shimada-Niwa, Ryusuke Niwa
Publikováno v:
PLoS Biology, Vol 16, Iss 9, p e2005004 (2018)
Stem cell maintenance is established by neighboring niche cells that promote stem cell self-renewal. However, it is poorly understood how stem cell activity is regulated by systemic, tissue-extrinsic signals in response to environmental cues and chan
Externí odkaz:
https://doaj.org/article/c4157ca06dcf448093dae9cd38fa5176
Autor:
Philipp Schlegel, Michael J Texada, Anton Miroschnikow, Andreas Schoofs, Sebastian Hückesfeld, Marc Peters, Casey M Schneider-Mizell, Haluk Lacin, Feng Li, Richard D Fetter, James W Truman, Albert Cardona, Michael J Pankratz
Publikováno v:
eLife, Vol 5 (2016)
NeuromedinU is a potent regulator of food intake and activity in mammals. In Drosophila, neurons producing the homologous neuropeptide hugin regulate feeding and locomotion in a similar manner. Here, we use EM-based reconstruction to generate the ent
Externí odkaz:
https://doaj.org/article/b6c88940c36447239044011d1f5f7449
Autor:
Alina Malita, Olga Kubrak, Takashi Koyama, Nadja Ahrentløv, Michael J. Texada, Stanislav Nagy, Kenneth V. Halberg, Kim Rewitz
Publikováno v:
Malita, A, Kubrak, O, Koyama, T, Ahrentløv, N, Texada, M J, Nagy, S, Halberg, K V & Rewitz, K 2022, ' A gut-derived hormone suppresses sugar appetite and regulates food choice in Drosophila ', Nature Metabolism, vol. 4, no. 11, pp. 1532-1550 . https://doi.org/10.1038/s42255-022-00672-z
Animals must adapt their dietary choices to meet their nutritional needs. How these needs are detected and translated into nutrient-specific appetites that drive food-choice behaviours is poorly understood. Here we show that enteroendocrine cells of
Autor:
Alina Malita, Olga Kubrak, Takashi Koyama, Nadja Ahrentløv, Kenneth V. Halberg, Michael J. Texada, Stanislav Nagy, Kim Rewitz
Animals must adapt their dietary choices to meet their nutritional needs. How these needs are detected and translated into nutrient-specific appetites that drive food-choice behaviors is poorly defined. Here, we show that the enteroendocrine cells (E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b524b88805763c301e9a7c4effde6c5
https://doi.org/10.1101/2022.03.02.482605
https://doi.org/10.1101/2022.03.02.482605
Publikováno v:
eLife, Vol 5 (2016)
Neuronal circuits are known to integrate nutritional information, but the identity of the circuit components is not completely understood. Amino acids are a class of nutrients that are vital for the growth and function of an organism. Here, we report
Externí odkaz:
https://doaj.org/article/a35572721f9a40ada1e22e95bc85a24e