Sequencing by avidity enables high accuracy with low reagent consumption

Autor: Sinan Arslan, Francisco J. Garcia, Minghao Guo, Matthew W. Kellinger, Semyon Kruglyak, Jake A. LeVieux, Adeline H. Mah, Haosen Wang, Junhua Zhao, Chunhong Zhou, Andrew Altomare, John Bailey, Matthew B. Byrne, Chiting Chang, Steve X. Chen, Byungrae Cho, Claudia N. Dennler, Vivian T. Dien, Derek Fuller, Ryan Kelley, Omid Khandan, Michael G. Klein, Michael Kim, Bryan R. Lajoie, Bill Lin, Yu Liu, Tyler Lopez, Peter T. Mains, Andrew D. Price, Samantha R. Robertson, Hermes Taylor-Weiner, Ramreddy Tippana, Austin B. Tomaney, Su Zhang, Minna Abtahi, Mark R. Ambroso, Rosita Bajari, Ava M. Bellizzi, Chris B. Benitez, Daniel R. Berard, Lorenzo Berti, Kelly N. Blease, Angela P. Blum, Andrew M. Boddicker, Leo Bondar, Chris Brown, Chris A. Bui, Juan Calleja-Aguirre, Kevin Cappa, Joshua Chan, Victor W. Chang, Katherine Charov, Xiyi Chen, Rodger M. Constandse, Weston Damron, Mariam Dawood, Nicole DeBuono, John D. Dimalanta, Laure Edoli, Keerthana Elango, Nikka Faustino, Chao Feng, Matthew Ferrari, Keith Frankie, Adam Fries, Anne Galloway, Vlad Gavrila, Gregory J. Gemmen, James Ghadiali, Arash Ghorbani, Logan A. Goddard, Adriana Roginski Guetter, Garren L. Hendricks, Jendrik Hentschel, Daniel J. Honigfort, Yun-Ting Hsieh, Yu-Hsien Hwang Fu, Scott K. Im, Chaoyi Jin, Shradha Kabu, Daniel E. Kincade, Shawn Levy, Yu Li, Vincent K. Liang, William H. Light, Jonathan B. Lipsher, Tsung-li Liu, Grace Long, Rui Ma, John M. Mailloux, Kyle A. Mandla, Anyssa R. Martinez, Max Mass, Daniel T. McKean, Michael Meron, Edmund A. Miller, Celyne S. Moh, Rachel K. Moore, Juan Moreno, Jordan M. Neysmith, Cassandra S. Niman, Jesus M. Nunez, Micah T. Ojeda, Sara Espinosa Ortiz, Jenna Owens, Geoffrey Piland, Daniel J. Proctor, Josua B. Purba, Michael Ray, Daisong Rong, Virginia M. Saade, Sanchari Saha, Gustav Santo Tomas, Nicholas Scheidler, Luqmanal H. Sirajudeen, Samantha Snow, Gudrun Stengel, Ryan Stinson, Michael J. Stone, Keoni J. Sundseth, Eileen Thai, Connor J. Thompson, Marco Tjioe, Christy L. Trejo, Greg Trieger, Diane Ni Truong, Ben Tse, Benjamin Voiles, Henry Vuong, Jennifer C. Wong, Chiung-Ting Wu, Hua Yu, Yingxian Yu, Ming Yu, Xi Zhang, Da Zhao, Genhua Zheng, Molly He, Michael Previte

Publikováno v: Nature Biotechnology.

We present avidity sequencing, a sequencing chemistry that separately optimizes the processes of stepping along a DNA template and that of identifying each nucleotide within the template. Nucleotide identification uses multivalent nucleotide ligands

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::134ecc28f29d15d85c9ac30057097e39
https://doi.org/10.1038/s41587-023-01750-7

Available Exclusively Online at

Autor: Sergentanis, Theodoros N Kastritis, Efstathios Terpos, Evangelos Dimopoulos, Meletios A Psaltopoulou, Theodora Khoury, Hanna J Goldberg, Stuart L Mauro, Michael J Stone, Richard M Deininger, Michael W others

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::ade229c6d703c28737cfeb8f5be0ea3e
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:2951114

The Spot Sign Score in Primary Intracerebral Hemorrhage Identifies Patients at Highest Risk of In-Hospital Mortality and Poor Outcome Among Survivors

Autor: Michael H. Lev, Joshua N. Goldstein, Alexandra Oleinik, R. Gilberto Gonzalez, Josser E Delgado Almandoz, H. Bart Brouwers, Albert J Yoo, Michael J. Stone, Javier Romero, Pamela W. Schaefer, Jonathan Rosand

Publikováno v: Stroke. 41:54-60

Background and Purpose— The spot sign score is a potent predictor of hematoma expansion in patients with primary intracerebral hemorrhage (ICH). We aim to determine the accuracy of this scoring system for the prediction of in-hospital mortality and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddda577d276fbc798cebc7517b1070d7
https://doi.org/10.1161/strokeaha.109.565382

Cognitive function following diabetic ketoacidosis in young children with type 1 diabetes

Autor: Simona Ghetti, Nathan Kuppermann, Arleta Rewers, Sage R. Myers, Jeff E. Schunk, Michael J. Stoner, Aris Garro, Kimberly S. Quayle, Kathleen M. Brown, Jennifer L. Trainor, Leah Tzimenatos, Andrew D. DePiero, Julie K. McManemy, Lise E. Nigrovic, Maria Y. Kwok, Cody S. Olsen, T. Charles Casper, Nicole S. Glaser, Pediatric Emergency Care Applied Research Network (PECARN) DKA FLUID Study Group

Publikováno v: Endocrinology, Diabetes & Metabolism, Vol 6, Iss 3, Pp n/a-n/a (2023)

Abstract Introduction Young children with type 1 diabetes (T1D) may be at particularly high risk of cognitive decline following diabetic ketoacidosis (DKA). However, studies of cognitive functioning in T1D typically examine school‐age children. The

Externí odkaz: https://doaj.org/article/617485ad77f54efbb39c97f29820666b

Marijuana use in children: An update focusing on pediatric tetrahydrocannabinol and cannabidiol use

Autor: Michael J. Stoner, Ann Dietrich, Samuel Hiu‐Fung Lam, Jessica J. Wall, Carmen Sulton, Emily Rose

Publikováno v: Journal of the American College of Emergency Physicians Open, Vol 3, Iss 4, Pp n/a-n/a (2022)

Abstract Cannabis is the most used recreational drug in the United States, and its use is increasing among children and adolescents. With the increase in legalized use, there have been increases in intentional and accidental cannabis exposure in the

Externí odkaz: https://doaj.org/article/db473aaa080a41dab70ea055eda61dbe