Zobrazeno 1 - 10
of 363
pro vyhledávání: '"Michael J. Sailor,‡ and"'
Autor:
Sanahan Vijayakumar, Robert G. Alberstein, Zhiyin Zhang, Yi-Sheng Lu, Adriano Chan, Charlotte E. Wahl, James S. Ha, Deborah E. Hunka, Gerry R. Boss, Michael J. Sailor, F. Akif Tezcan
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract The sensitivity and responsiveness of living cells to environmental changes are enabled by dynamic protein structures, inspiring efforts to construct artificial supramolecular protein assemblies. However, despite their sophisticated structur
Externí odkaz:
https://doaj.org/article/c97e1474484349a58911265108dfaca3
Publikováno v:
Drug Delivery, Vol 27, Iss 1, Pp 703-711 (2020)
Mesoporous silica has attracted significant attention in the drug delivery area; however, impurities can be a source of toxicity. The current study used commercial microparticles produced at large scale in a well-controlled environment. Micrometer si
Externí odkaz:
https://doaj.org/article/a73e796871304aeba27543cf7d5d6a1e
Autor:
Ying Xiao, Kyung Seek Choi, David Warther, Kristyn Huffman, Stephanie Landeros, William R. Freeman, Michael J. Sailor, Lingyun Cheng
Publikováno v:
Drug Delivery, Vol 27, Iss 1, Pp 1461-1473 (2020)
Proliferative vitreoretinopathy (PVR) is a significant threat for vision recovery from retinal detachment or ocular trauma. Currently, no approved pharmacological intervention to prevent PVR. Daunorubicin (DNR) and dexamethasone (DEX) were sequential
Externí odkaz:
https://doaj.org/article/f5863a4482744ff7bb369780dbb85946
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
In the context of increasing bacterial antibiotic-resistance, gene therapy that targets the immune system to clear infection is a major goal. Here the authors show a silicon based nanosystem that modulates the macrophage response in an in vivo model
Externí odkaz:
https://doaj.org/article/098171d737834a66a71effee6e976c20
New model of proliferative vitreoretinopathy in rabbit for drug delivery and pharmacodynamic studies
Autor:
Sang Woong Moon, Yaoyao Sun, David Warther, Kristyn Huffman, William R. Freeman, Michael J. Sailor, Lingyun Cheng
Publikováno v:
Drug Delivery, Vol 25, Iss 1, Pp 600-610 (2018)
Blinding retinal diseases become more epidemic as the population ages. These diseases, such as diabetic retinopathy and macular edema, are of chronic nature and require protracted drug presence at the disease site. A sustained intravitreal porous sil
Externí odkaz:
https://doaj.org/article/b96d9110b7b64dd8a94bb4a5ff49a15b
Autor:
Michael J. Sailor
Publikováno v:
ACS Sensors. 8:1868-1870
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::862a9ca425099f3cf751d8eb20ef9477
https://doi.org/10.1021/acssensors.3c00920
https://doi.org/10.1021/acssensors.3c00920
Autor:
Joel F Grondek, Kristyn Huffman, Ella Jiyoon Lee, Melina Cavichini, Alexandra Warter, Fritz Gerald P Kalaw, Anna Heinke, Ruhan Fan, Lingyun Cheng, Michael J Sailor, William R Freeman
Publikováno v:
Nanomedicine. 17:2089-2108
Aim: To evaluate an intravitreally injected nanoparticle platform designed to deliver VEGF-A siRNA to inhibit retinal neovascular leakage as a new treatment for proliferative diabetic retinopathy and diabetic macular edema. Materials & methods: Fusog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::11fff36c86d09b4665370a7b2d371fca
https://doi.org/10.2217/nnm-2022-0255
https://doi.org/10.2217/nnm-2022-0255
Autor:
Moonkyoung Jeong, Yuna Jung, Junyong Yoon, Jinyoung Kang, Seo Hyeon Lee, Woojin Back, Hyoyeon Kim, Michael J. Sailor, Dokyoung Kim, Ji-Ho Park
Publikováno v:
ACS Nano. 16:16118-16132
The lack of drugs that target both disease progression and tissue preservation makes it difficult to effectively manage rheumatoid arthritis (RA). Here, we report a porous silicon-based nanomedicine that efficiently delivers an antirheumatic drug to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d6776acb49a33d98074af9413f3f6fb
https://doi.org/10.1021/acsnano.2c04491
https://doi.org/10.1021/acsnano.2c04491
Autor:
Lauren E. Waggoner, Jinyoung Kang, Jonathan M. Zuidema, Sanahan Vijayakumar, Alan A. Hurtado, Michael J. Sailor, Ester J. Kwon
Publikováno v:
Bioconjugate chemistry. 33(9)
Traumatic brain injury (TBI) is a major cause of disability and death among children and young adults in the United States, yet there are currently no treatments that improve the long-term brain health of patients. One promising therapeutic for TBI i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d3fecde83474466337d42e349fa9184
https://pubmed.ncbi.nlm.nih.gov/36017941
https://pubmed.ncbi.nlm.nih.gov/36017941
Autor:
Maxim B. Gongalsky, Julia V. Kargina, Jose F. Cruz, Juan F. Sánchez-Royo, Vladimir S. Chirvony, Liubov A. Osminkina, Michael J. Sailor
Publikováno v:
Frontiers in Chemistry, Vol 7 (2019)
We propose a rapid, one-pot method to generate photoluminescent (PL) mesoporous silicon nanoparticles (PSiNPs). Typically, mesoporous silicon (meso-PSi) films, obtained by electrochemical etching of monocrystalline silicon substrates, do not display
Externí odkaz:
https://doaj.org/article/a65ee97b77164b5ab1a758fbe8782345