Zobrazeno 1 - 6 of 6 pro vyhledávání: '"Michael J. Renzi"'
1
A Dominant Negative Receptor for Specific Secreted Semaphorins Is Generated by Deleting an Extracellular Domain from Neuropilin-1
Autor: Leonard Feiner, Adam M. Koppel, Jonathan A. Raper, Michael J Renzi
Publikováno v: The Journal of Neuroscience. 19:7870-7880
Neuropilins have recently been characterized as receptors for secreted semaphorins. Here, we report the generation of a dominant negative form of neuropilin-1 by the deletion of one of its extracellular domains. Expression of this variant in cultured
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82b8d58f61822f3f76ddd6e33ee932df
https://doi.org/10.1523/jneurosci.19-18-07870.1999
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2
A family of molecules related to collapsin in the embryonic chick nervous system
Autor: Susannah Chang, Jie Li, Iain T. Shepherd, Michael J Renzi, Yuling Luo, Jonathan A. Raper
Publikováno v: Neuron. 14(6):1131-1140
Signaling molecules with either attractive or repulsive effects on specific growth cones are likely to play a role in guiding axons to their appropriate targets. A chick brain glycoprotein, collapsin, has been shown to be a good candidate for a repul
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69a86485f8d74b3e4486d45a49db001b
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4
Orally active benzamide antipsychotic agents with affinity for dopamine D2, serotonin 5-HT1A, and adrenergic alpha1 receptors
Autor: Alfonzo D. Jordan, Allen B. Reitz, Jeffry L. Vaught, Coralie B. Davis, Ellen E. Codd, Richard P. Shank, Malcolm K. Scott, Mary R. Schott, Bruce E. Maryanoff, Ellen W. Baxter, Michael J. Renzi, Mcdonnell Mark E, Cynthia A. Maryanoff, Powell Eugene
Publikováno v: Journal of medicinal chemistry. 41(12)
New antipsychotic drugs are needed because current therapy is ineffective for many schizophrenics and because treatment is often accompanied by extrapyramidal symptoms and dyskinesias. This paper describes the design, synthesis, and evaluation of a s
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1cdbcdd61e776c73f9c6f8abb2d4855
https://pubmed.ncbi.nlm.nih.gov/9622541
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5
N-aryl-N'-benzylpiperazines as potential antipsychotic agents
Autor: Allen B. Reitz, E. W. Baxter, Bruce E. Maryanoff, Marta E. Ortegon, Debra J. Bennett, E. E. Codd, Michael J. Renzi, E. A. Malloy, Mcdonnell Mark E, Alfonzo D. Jordan
Publikováno v: Journal of medicinal chemistry. 38(21)
N 1 -(2-Alkoxyphenyl)piperazines additionally containing an N 4 -benzyl group bearing alcohol, amide, imide, or hydantoin functionalities were prepared and evaluated in the conditioned avoidance response (CAR) test predictive of clinical antipsychoti
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a2cb0c2ec98853ffe417a880a3c8858
https://pubmed.ncbi.nlm.nih.gov/7473548
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6
Olfactory Sensory Axons Expressing a Dominant–Negative Semaphorin Receptor Enter the CNS Early and Overshoot Their Target
Autor: Tamara Wexler, Michael J Renzi, Jonathan A. Raper
Publikováno v: Neuron. (2):437-447
Sensory axons extend from the chick olfactory epithelium to the telencephalon well before the maturation of their target, the olfactory bulb. During a waiting period of several days, olfactory axons arrive and accumulate outside the CNS while the bul
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a080b41371b0b4eb80b2c0268700171
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