Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Michael J. Pepi"'
Autor:
Michael J. Pepi, Shibin Chacko, Nicole Kopetz, Helena I.M. Boshoff, Gregory D. Cuny, Lizbeth Hedstrom
Publikováno v:
Bioorganicmedicinal chemistry letters.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a371efcdf32f1e8861ec0d0550851a5d
https://pubmed.ncbi.nlm.nih.gov/36572353
https://pubmed.ncbi.nlm.nih.gov/36572353
Autor:
Michael J, Pepi, Shibin, Chacko, Gary M, Marqus, Vinayak, Singh, Zhe, Wang, Kyle, Planck, Ryan T, Cullinane, Penchala N, Meka, Deviprasad R, Gollapalli, Thomas R, Ioerger, Kyu Y, Rhee, Gregory D, Cuny, Helena I M, Boshoff, Lizbeth, Hedstrom
Publikováno v:
ACS Infect Dis
New drugs and new targets are urgently needed to treat tuberculosis. We discovered the D-phenylalanine-benzoxazole Q112 displays potent antibacterial activity against Mycobacterium tuberculosis (Mtb) in multiple media and in macrophage infections. Me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::31a1ae83ee43ca779a5028edd621871f
https://pubmed.ncbi.nlm.nih.gov/35015509
https://pubmed.ncbi.nlm.nih.gov/35015509
Autor:
Michael J. Pepi, Shibin Chacko, Gary M. Marqus, Vinayak Singh, Zhe Wang, Kyle Planck, Ryan T. Cullinane, Penchala N. Meka, Deviprasad R. Gollapalli, Thomas R. Ioerger, Kyu Y. Rhee, Gregory D. Cuny, Helena I.M. Boshoff, Lizbeth Hedstrom
This is the accepted manuscript version of the work published in its final form as Pepi, M. J., Chacko, S., Marqus, G. M., Singh, V., Wang, Z., Planck, K., Cullinane, R. T., Meka, P. N., Gollapalli, D. R., Ioerger, T. R., Rhee, K. Y., Cuny, G. D., Bo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19ab59662d39e9e443744b09196020de
Autor:
Shibin Chacko, Helena I. M. Boshoff, Vinayak Singh, Davide M. Ferraris, Deviprasad R. Gollapalli, Minjia Zhang, Ann P. Lawson, Michael J. Pepi, Andrzej Joachimiak, Menico Rizzi, Valerie Mizrahi, Gregory D. Cuny, Lizbeth Hedstrom
Publikováno v:
Journal of Medicinal Chemistry. 64:18233-18234
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aca9679d608b3b2df3453a0e6410e709
https://doi.org/10.1021/acs.jmedchem.1c01923
https://doi.org/10.1021/acs.jmedchem.1c01923
Autor:
Lizbeth Hedstrom, Davide M. Ferraris, Shibin Chacko, Michael J. Pepi, Minjia Zhang, Helena I. Boshoff, Deviprasad R. Gollapalli, Vinayak Singh, Valerie Mizrahi, Gregory D. Cuny, Andrzej Joachimiak, Ann P. Lawson, Menico Rizzi
Publikováno v:
Journal of Medicinal Chemistry. 61:4739-4756
New drugs and molecular targets are urgently needed to address the emergence and spread of drug-resistant tuberculosis. Mycobacterium tuberculosis ( Mtb) inosine 5'-monophosphate dehydrogenase 2 ( MtbIMPDH2) is a promising yet controversial potential
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38e74d2091981d050618d946a8dcd9ec
https://doi.org/10.1021/acs.jmedchem.7b01839
https://doi.org/10.1021/acs.jmedchem.7b01839
Publikováno v:
Polyhedron. 143:215-222
A series of compounds comprised of N-heterocyclic phosphido-containing ligands bound to a Co(CO)2 fragment are explored computationally using density functional theory (DFT). Computational methods are used to identify changes in the electronic struct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::afc887ec7c2762aafbaa21c701461080
https://doi.org/10.1016/j.poly.2017.11.015
https://doi.org/10.1016/j.poly.2017.11.015