Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Michael J. Pazin"'
Autor:
Ananda L. Roy, Richard S. Conroy, Veronica G. Taylor, Judy Mietz, Ian M. Fingerman, Michael J. Pazin, Phillip Smith, Carolyn M. Hutter, Dinah S. Singer, Elizabeth L. Wilder
Publikováno v:
Molecular Cell. 83:335-342
Autor:
Rebecca Casaday Potts, Peisu Zhang, Andrea L Wurster, Patricia Precht, Mohamed R Mughal, William H Wood, Yonqing Zhang, Kevin G Becker, Mark P Mattson, Michael J Pazin
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24515 (2011)
CHD5 is frequently deleted in neuroblastoma and is a tumor suppressor gene. However, little is known about the role of CHD5 other than it is homologous to chromatin remodeling ATPases. We found CHD5 mRNA was restricted to the brain; by contrast, most
Externí odkaz:
https://doaj.org/article/b6dc22d1f8ee429592a1873421761779
Autor:
Pouya Kheradpour, Yi-Chieh Wu, Michael Snyder, Steven E. Brenner, Trupti Kawli, Mark Gerstein, Lixia Jiang, Robert Terrell, Anshul Kundaje, Wei Niu, Matthew Slattery, Manolis Kellis, Peter J. Good, LaDeana W. Hillier, Robert H. Waterston, Koon-Kiu Yan, Haiyan Huang, E. Jay Rehm, Carlos L. Araya, Philip Cayting, J. Janette, Jingyi Jessica Li, Chao Cheng, Elise A. Feingold, Alan P. Boyle, Michael J. Pazin, Peter Weisdepp, Joel Rozowsky, Lijia Ma, Peter J. Bickel, Dan Xie, D. Vafeados, Kathryn E. Gardner, Kevin P. White, Valerie Reinke, Dionna M. Kasper, Cathleen M. Brdlik, Daifeng Wang, Yong Cheng, Rebecca Spokony
Publikováno v:
Boyle, AP; Araya, CL; Brdlik, C; Cayting, P; Cheng, C; Cheng, Y; et al.(2014). Comparative analysis of regulatory information and circuits across distant species. Nature, 512(7515), 453-456. doi: 10.1038/nature13668. UC Berkeley: Retrieved from: http://www.escholarship.org/uc/item/1rj5c5wg
Nature, vol 512, iss 7515
PMC
Nature
Nature, vol 512, iss 7515
PMC
Nature
Despite the large evolutionary distances between metazoan species, they can show remarkable commonalities in their biology, and this has helped to establish fly and worm as model organisms for human biology. Although studies of individual elements an
Autor:
Gang Fang, LaDeana W. Hillier, Brenton R. Graveley, Ali Mortazavi, Norbert Perrimon, Nathan Boley, Jingyi Jessica Li, William C. Spencer, James B. Brown, Chau Huynh, Roger A. Hoskins, Mark Gerstein, Ann S. Hammonds, Sarah Djebali, Sonali Jha, Kenneth H. Wan, Cédric Howald, Raymond K. Auerbach, Chenghai Xue, Haiyan Huang, Jorg Drenkow, Elise A. Feingold, Julien Lagarde, Daifeng Wang, Dmitri D. Pervouchine, Thomas R. Gingeras, Guilin Wang, Peter Cherbas, Brent Ewing, Chao Di, Gary Saunders, Benjamin W. Booth, Joel Rozowsky, Yan Zhang, Anastasia Samsonova, Dionna M. Kasper, Cristina Sisu, Marcus H. Stoiber, Jiayu Wen, Michael O. Duff, Felix Schlesinger, Gennifer E. Merrihew, Sara Olson, Susan E. Celniker, Burak H. Alver, Chao Cheng, Gemma E. May, Alexandre Reymond, Carrie A. Davis, Alexander Dobin, Max E. Boeck, Roger P. Alexander, Michael J. Pazin, Peter J. Park, Adam Frankish, Lucy Cherbas, Zhi Lu, Kevin Y. Yip, Henry Zheng, Owen Thompson, Jing Leng, Kathie L. Watkins, Andrea Tanzer, Valerie Reinke, Rebecca McWhirter, Eric C. Lai, Steven E. Brenner, Robert H. Waterston, Koon-Kiu Yan, Masaomi Kato, Roderic Guigó, Huaien Wang, Kimberly Bell, Pnina Strasbourger, Baikang Pei, Jen Harrow, Long Hu, Chris Zaleski, Rabi Murad, Thomas C. Kaufman, Erik Ladewig, Robert R. Kitchen, Anurag Sethi, Kejia Wen, Guanjun Gao, Arif Harmanci, Megan Fastuca, Brian Oliver, Frank J. Slack, David M. Miller, Tim Hubbard, Garrett Robinson, Peter J. Good, Peter J. Bickel, Michael J. MacCoss, Li Yang
Publikováno v:
Nature
Recercat. Dipósit de la Recerca de Catalunya
instname
NATURE
Nature, vol 512, iss 7515
Nature, vol. 512, no. 7515, pp. 445-448
Recercat. Dipósit de la Recerca de Catalunya
instname
NATURE
Nature, vol 512, iss 7515
Nature, vol. 512, no. 7515, pp. 445-448
The transcriptome is the readout of the genome. Identifying common features in it across distant species can reveal fundamental principles. To this end, the ENCODE and modENCODE consortia have generated large amounts of matched RNA-sequencing data fo
Autor:
Michael J. Pazin, Andrea L. Wurster
Publikováno v:
Biochemistry and Cell Biology. 90:1-13
One of the best studied systems for mammalian chromatin remodeling is transcriptional regulation during T cell development. The variety of these studies have led to important findings in T cell gene regulation and cell fate determination. Importantly
Publikováno v:
Molecular Immunology. 48:2178-2188
We investigated gene regulation at the IL-3/GM-CSF gene cluster. We found BRG1, a SWI/SNF remodeling ATPase, bound a distal element, CNSa. BRG1 binding was strongest in differentiated, stimulated T helper cells, paralleling IL-3 and GM-CSF expression
Autor:
Michael J. Pazin, Patricia Precht, Supriyo De, Kevin G. Becker, William H. Wood, Andrea L. Wurster
Publikováno v:
Molecular and Cellular Biology. 31:1512-1527
T helper cell differentiation and activation require specific transcriptional programs accompanied by changes in chromatin structure. However, little is known about the chromatin remodeling enzymes responsible. We performed genome-wide analysis to de
Autor:
Andrea L. Wurster, Michael J. Pazin
Publikováno v:
Molecular and Cellular Biology. 28:7274-7285
During T helper cell differentiation, distinct programs of gene expression play a key role in defining the immune response to an environmental challenge. How chromatin remodeling events at the associated cytokine loci control differentiation is not k
Publikováno v:
Endocrinology. 150:1122-1131
S-glutathionylation is a physiological, reversible protein modification of cysteine residues with glutathione in response to mild oxidative stress. Because the key cell growth regulator signal transducer and activator of transcription (STAT) 3 is par
Autor:
Mark P. Mattson, Caroline M. Dilley, Catherine M. Schwartz, Kevin G. Becker, Peisu Zhang, Robert P. Wersto, Michael J. Pazin
Publikováno v:
Current Biology. 18:1489-1494
Removal of TRF2, a telomere shelterin protein, recapitulates key aspects of telomere attrition including the DNA-damage response and cell-cycle arrest [1]. Distinct from the response of proliferating cells to loss of TRF2 [2, 3], in rodent non-cyclin