Zobrazeno 1 - 10
of 138
pro vyhledávání: '"Michael J. Parsons"'
Autor:
Tori R. Tucker, Courtney A. Knitter, Deena M. Khoury, Sheida Eshghi, Sophia Tran, Abigail V. Sharrock, Travis J. Wiles, David F. Ackerley, Jeff S. Mumm, Michael J. Parsons
Publikováno v:
Disease Models & Mechanisms, Vol 16, Iss 8 (2023)
Externí odkaz:
https://doaj.org/article/e6303cd05e3f43ad9e16ca58bfd17559
Autor:
Danhua Zhang, Keith P. Gates, Lindsey Barske, Guangliang Wang, Joseph J. Lancman, Xin-Xin I. Zeng, Megan Groff, Kasper Wang, Michael J. Parsons, J. Gage Crump, P. Duc Si Dong
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
The hepatopancreatic duct cells connect liver hepatocytes and pancreatic acinar cells to the intestine, but the mechanism for their lineage specification is unclear. Here, the authors reveal that Notch ligands Jagged1b and Jagged2b induce duct cell l
Externí odkaz:
https://doaj.org/article/9a869d75f80549c8a2ff75e1bc7269a8
Autor:
Edoardo Balzani, Glenda Lassi, Silvia Maggi, Siddharth Sethi, Michael J. Parsons, Michelle Simon, Patrick M. Nolan, Valter Tucci
Publikováno v:
Cell Reports, Vol 16, Iss 3, Pp 615-621 (2016)
An AT motif-dependent axis, modulated by the transcription factor Zfhx3, influences the circadian clock in mice. In particular, gain of function of Zfhx3 significantly shortens circadian rhythms and alters the transcriptional activity of an important
Externí odkaz:
https://doaj.org/article/1341c4559ff04eb6a552ef9fb4f895a2
Autor:
Michael J. Parsons
Publikováno v:
Revista Gearte, Vol 1, Iss 3 (2014)
Este artigo trata de uma abordagem para a significação de imagens através de metáforas, baseando-se nas atuais discussões sobre a metáfora sob a perspectiva da cognição incorporada. Discute por meio de exemplos alguns modos em que a metáfora
Externí odkaz:
https://doaj.org/article/8503f34aa37a4aaa8fa263aa2cefb208
Publikováno v:
Tissue Engineering Part A. 27:1140-1150
Transforming growth factor beta (TGFβ) signaling is required for in vitro chondrogenesis. In animal models of osteoarthritis (OA), TGFβ receptor alterations are detected in chondrocytes in severe O...
Autor:
Seunghoon Lee, Michael J. Parsons, Daniel A. Lee, Hyewon Park, Sungjin Ko, Mizuki Azuma, Minwook Kim, Donghun Shin, Juhoon So, David A. Prober
Publikováno v:
Hepatology
Background and Aims: The liver is a highly regenerative organ, but its regenerative capacity is compromised in severe liver injury settings. In chronic liver diseases, the number of liver progenitor cells (LPCs) correlates proportionally to disease s
Autor:
Allen Goodman, Michael C. Kolios, Holger Hennig, Michael J. Parsons, Anne Wilson, Olaf Wolkenhauer, Shantanu Singh, Stefanie Siegert, Anne E. Carpenter, Joseph A. Sebastian, Ruben N. Pinto, Tracey R. Turner, Olga Mykhailova, Jason P. Acker, Minh Doan, Paul Rees, Juan C. Caicedo, Aline Roch, Claire McQuin
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol. 117, no. 35, pp. 21381-21390
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America
Significance We developed a strategy to avoid human subjectivity by assessing the quality of red blood cells using imaging flow cytometry and deep learning. We successfully automated traditional expert assessment by training a computer with example i
Autor:
Joseph R. Hunt, Lindsey R. Guthrie, Justin Hendrix, William S. Owen, Michael S. Bible, Michael S. Lowry, Emma F. Dohmeier, Michael J. Parsons
Publikováno v:
MRS Communications. 10:91-97
To investigate the manipulation of electromagnetic properties of two-dimensional materials, this effort characterizes charge transfer behavior of colloidal COF-5 (covalent organic framework) in the presence of various metal ions. A series of metal ch
Autor:
Guangliang Wang, Surendra K Rajpurohit, Fabien Delaspre, Steven L Walker, David T White, Alexis Ceasrine, Rejji Kuruvilla, Ruo-jing Li, Joong S Shim, Jun O Liu, Michael J Parsons, Jeff S Mumm
Publikováno v:
eLife, Vol 4 (2015)
Whole-organism chemical screening can circumvent bottlenecks that impede drug discovery. However, in vivo screens have not attained throughput capacities possible with in vitro assays. We therefore developed a method enabling in vivo high-throughput
Externí odkaz:
https://doaj.org/article/6bc5a75f96814fc3aa7ccaecb3f5d1b1
Autor:
Miquel Angel Pujana, Michael J. Parsons, Hal K. Berman, Alison E. Casey, Luis Palomero, Kazeera Aliar, Thomas Kislinger, Swami R. Narala, Hyun-Chul Kim, Paul Waterhouse, Hofer S, Rama Khokha, Francesca Mateo, Mathepan Mahendralingam
It has long been assumed that all normal cells have the same capacity to engage homologous recombination (HR) and non-homologous end joining (NHEJ) to repair DNA double-strand breaks (DSBs), a concept exploited for DNA-damaging chemotherapeutics. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b8196882f05813d0581edeca35c6e37
https://doi.org/10.1101/2021.05.14.444217
https://doi.org/10.1101/2021.05.14.444217