Zobrazeno 1 - 10
of 404
pro vyhledávání: '"Michael J. Palmer"'
Autor:
Berghmans, Mieke
Publikováno v:
Development in Practice, 2014 Sep 01. 24(7), 930-930.
Externí odkaz:
https://www.jstor.org/stable/24565868
Publikováno v:
Cancer Medicine, Vol 10, Iss 9, Pp 3026-3034 (2021)
Abstract Background Missing patient reported outcomes data threaten the validity of PRO‐specific findings and conclusions from randomized controlled trials by introducing bias due to data missing not at random. Clinical Research Associates are a la
Externí odkaz:
https://doaj.org/article/d4160077a1d44c25803a36ab731ff5b4
Publikováno v:
PLoS ONE, Vol 17, Iss 12, p e0279412 (2022)
Legacy arsenic (As) contamination from past mining operations remains an environmental concern in lakes of the Yellowknife area (Northwest Territories, Canada) due to its post-depositional mobility in sediment and potential for continued remobilizati
Externí odkaz:
https://doaj.org/article/7942105f2bc0424a8f1299cbc357462a
Autor:
Ian H. Gilbert
Publikováno v:
ChemMedChem. 7:1859-1859
Autor:
Yaqing Jiao, Sarah Preston, Anson V. Koehler, Andreas J. Stroehlein, Bill C. H. Chang, Kaylene J. Simpson, Karla J. Cowley, Michael J. Palmer, Benoît Laleu, Timothy N. C. Wells, Abdul Jabbar, Robin B. Gasser
Publikováno v:
Parasites & Vectors, Vol 10, Iss 1, Pp 1-7 (2017)
Abstract Background In partnership with the Medicines for Malaria Venture (MMV), we screened a collection (‘Stasis Box’) of 400 compounds (which have been in clinical development but have not been approved for illnesses other than neglected infec
Externí odkaz:
https://doaj.org/article/42151eb5042e4f648e96208755c17b05
Autor:
Paul M. O’Neill, Richard K. Amewu, Susan A. Charman, Sunil Sabbani, Nina F. Gnädig, Judith Straimer, David A. Fidock, Emma R. Shore, Natalie L. Roberts, Michael H.-L. Wong, W. David Hong, Chandrakala Pidathala, Chris Riley, Ben Murphy, Ghaith Aljayyoussi, Francisco Javier Gamo, Laura Sanz, Janneth Rodrigues, Carolina Gonzalez Cortes, Esperanza Herreros, Iñigo Angulo-Barturén, María Belén Jiménez-Díaz, Santiago Ferrer Bazaga, María Santos Martínez-Martínez, Brice Campo, Raman Sharma, Eileen Ryan, David M. Shackleford, Simon Campbell, Dennis A. Smith, Grennady Wirjanata, Rintis Noviyanti, Ric N. Price, Jutta Marfurt, Michael J. Palmer, Ian M. Copple, Amy E. Mercer, Andrea Ruecker, Michael J. Delves, Robert E. Sinden, Peter Siegl, Jill Davies, Rosemary Rochford, Clemens H. M. Kocken, Anne-Marie Zeeman, Gemma L. Nixon, Giancarlo A. Biagini, Stephen A. Ward
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Artemisinin-resistantPlasmodium is an increasing problem. Here, using a medicinal chemistry programme, the authors identify a tetraoxane-based drug candidate that shows no cross-resistance with an artemisinin-resistant strain (PfK13-C580Y) and is eff
Externí odkaz:
https://doaj.org/article/d0b09995908d4fd1a466aa398f702f2f
Autor:
Yaqing Jiao, Sarah Preston, Hongjian Song, Abdul Jabbar, Yuxiu Liu, Jonathan Baell, Andreas Hofmann, Dana Hutchinson, Tao Wang, Anson V. Koehler, Gillian M. Fisher, Katherine T. Andrews, Benoît Laleu, Michael J. Palmer, Jeremy N. Burrows, Timothy N. C. Wells, Qingmin Wang, Robin B. Gasser
Publikováno v:
Parasites & Vectors, Vol 10, Iss 1, Pp 1-7 (2017)
Abstract Background In this study, we tested five series of pyrazole-5-carboxamide compounds (n = 55) for activity against parasitic stages of the nematode Haemonchus contortus (barber’s pole worm), one of the most pathogenic parasites of ruminants
Externí odkaz:
https://doaj.org/article/23c9a23e634d4f5fa18d8f7b336a309d
Autor:
John Chételat, Michael J. Palmer, Katrina Paudyn, Heather Jamieson, Marc Amyot, Reed Harris, Raymond Hesslein, Nicolas Pelletier, Ines Peraza
Publikováno v:
Journal of Hazardous Materials. 452:131230
Publikováno v:
Cold Regions Science and Technology. 210:103808
Autor:
Sergio Wittlin, Sachel Mok, Benoît Laleu, Anwu Zhou, Susan A. Charman, Margaret A. Phillips, Tomas Yeo, David A. Fidock, Alisje Churchyard, Joseph M. Ready, Francisco-Javier Gamo, Ioanna Deni, John Okombo, Bruce A. Posner, Aloysus K. Lawong, Jessica L. Bridgford, Elizabeth A. Winzeler, Benigno Crespo, Michael J. Palmer, Hanspeter Niederstrasser, Josefine Striepen, Suraksha Gahalawat, Jake Baum, Nimisha Mittal
Publikováno v:
Journal of Medicinal Chemistry. 64:2739-2761
Malaria control programs continue to be threatened by drug resistance. To identify new antimalarials, we conducted a phenotypic screen and identified a novel tetrazole-based series that shows fast-kill kinetics and a relatively low propensity to deve