Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Michael J. Mertensotto"'
Autor:
Daniel A. Saltzman, Janet L. Schottel, Michael J. Mertensotto, Arnold S. Leonard, Lance B. Augustin
Publikováno v:
Surgery. 163:509-514
Immunotherapies for cancer treatment have demonstrated substantial promise even though toxicities and development of tumor resistance limit their effectiveness. A combinatorial approach using immunotherapy with other treatment modalities may decrease
Autor:
Daniel A. Saltzman, Jeremy Drees, Lance B. Augustin, Janet L. Schottel, Michael J. Mertensotto
Publikováno v:
Journal of Cancer
Attenuated Salmonella enterica serovar Typhimurium (S. Typhimurium) has been developed as a vector to deliver therapeutic agents to tumors. The potential of S. Typhimurium in cancer therapy is largely due to its reported propensity to accumulate at g
Autor:
Daniel A. Saltzman, Michael J. Mertensotto, Janet L. Schottel, Jeremy Drees, Lance B. Augustin
Publikováno v:
Current microbiology. 70(3)
The efficacy of live attenuated bacterial vectors is dependent upon the fine-tuning of a strain’s immunogenicity and its virulence. Strains are often engineered to deliver heterologous antigens, but soluble expression of recombinant proteins can be
Autor:
Michael J. Mertensotto, Arnold S. Leonard, Jeremy Drees, Lance B. Augustin, Daniel A. Saltzman, Janet L. Schottel
Publikováno v:
Protein expression and purification. 94
Programmed death ligand 1 (PD-L1), is an important regulator of T-cell activation and has emerged as an important target for cancer immunotherapy. Single chain variable fragments (scFvs) have several desirable characteristics and are an attractive al