X-ray diffraction of metastable structures from supercooled liquid hydrogen

Autor: Luke B. Fletcher, Abraham L. Levitan, Emma E. McBride, Jongjin B. Kim, Eduardo P. Alves, Andrew Aquila, Mungo Frost, Sebastian Goede, Grace King, Thomas J. Lane, Mengning Liang, Michael J. MacDonald, Benjamin K. Ofori-Okai, Christopher Schönwälder, Peihao Sun, Jerome B. Hastings, Sebastien Boutet, Siegfried H. Glenzer

Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)

Abstract We report time resolved observations of the crystallization from liquid hydrogen, supercooled to temperatures below the melting point, using 11.2 keV X-ray diffraction from the Linac Coherent Light Source (LCLS). Changes to the metastable so

Externí odkaz: https://doaj.org/article/59b89c0f3ed9410ba6fc2bbc9576451f

Knockdown of ATP citrate lyase in pancreatic beta cells does not inhibit insulin secretion or glucose flux and implicates the acetoacetate pathway in insulin secretion

Autor: Mahmoud El Azzouny, Melissa J. Longacre, Israr-ul H. Ansari, Robert T. Kennedy, Charles F. Burant, Michael J. MacDonald

Publikováno v: Molecular Metabolism, Vol 5, Iss 10, Pp 980-987 (2016)

Objective: Glucose-stimulated insulin secretion in pancreatic beta cells requires metabolic signals including the generation of glucose-derived short chain acyl-CoAs in the cytosol from mitochondrially-derived metabolites. One concept of insulin secr

Externí odkaz: https://doaj.org/article/6f3c5388e8594e419be8953d195d26ab

The data-driven future of high-energy-density physics

Autor: Michael J MacDonald, Carl Shneider, Patrick Knapp, Suzan Başeğmez du Pree, Derek Mariscal, B. Kettle, Will Trickey, Marta Fajardo, Suzanne Ali, Ben Williams, M. J. V. Streeter, Jonathan Citrin, J. J. Ruby, Gemma J. Anderson, Bogdan Kustowski, P. W. Hatfield, S. J. Rose, J. Luc Peterson, Jim Gaffney, Luca Antonelli, Madison E. Martin, Taisuke Nagayama, Charlotte Palmer

Publikováno v: Nature, 593(7859), 351-361
Hatfield, P W, Gaffney, J A, Anderson, G J, Ali, S, Antonelli, L, Başeğmez du Pree, S, Citrin, J, Fajardo, M, Knapp, P, Kettle, B, Kustowski, B, MacDonald, M J, Mariscal, D, Martin, M E, Nagayama, T, Palmer, C A J, Peterson, J L, Rose, S, Ruby, J J, Shneider, C, Streeter, M J V, Trickey, W & Williams, B 2021, ' The data-driven future of high-energy-density physics ', Nature, vol. 593, pp. 351-361 . https://doi.org/10.1038/s41586-021-03382-w
Nature, 593, 351-361

The study of plasma physics under conditions of extreme temperatures, densities and electromagnetic field strengths is significant for our understanding of astrophysics, nuclear fusion and fundamental physics. These extreme physical systems are stron

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::282476a422c229b06c63609df6a069f5
https://doi.org/10.1038/s41586-021-03382-w

Uncovering patterns of freshwater positive interactions using meta‐analysis: Identifying the roles of common participants, invasive species and environmental context

Autor: Benjamin B. Tumolo, Laura A. Burkle, Jose A. Sanchez‐Ruiz, Lindsey K. Albertson, Zachary Maguire, Michael J. MacDonald, Jaris Veneros, Michelle A. Briggs, Sierra Quinn

Publikováno v: Ecology Letters. 24:594-607

Positive interactions are sensitive to human activities, necessitating synthetic approaches to elucidate broad patterns and predict future changes if these interactions are altered or lost. General understanding of freshwater positive interactions ha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a29ffb1b0cc87e87ec4eacac94d78ca2
https://doi.org/10.1111/ele.13664

A Novel Intron-Encoded Neuropilin-1 Isoform in Pancreatic Islets Associated With Very Young Age of Onset of Type 1 Diabetes

Autor: Michael J. MacDonald, Israr-ul H. Ansari, Amy S. Riedemann, Scott W. Stoker, Jens C. Eickhoff, Peter J. Chlebeck, Luis A. Fernandez, Melissa J. Longacre

Publikováno v: Diabetes. 71(9)

Net synthesis of pancreatic beta cells peaks before two years of life. Beta cell mass is set within the first five years of life. Inframe translational readthrough of the NRP1 gene exon 9 into intron 9 generates a truncated neuropilin-1 protein lacki

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c0c650ff919ee359b032fd4b94d43e5
https://pubmed.ncbi.nlm.nih.gov/35713886