Zobrazeno 1 - 10
of 137
pro vyhledávání: '"Michael J. Lind"'
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 8, Iss , Pp 317-329 (2017)
Malignant pleural mesothelioma (MPM) is associated with an extremely poor prognosis, and most patients initially are or rapidly become unresponsive to platinum-based chemotherapy. MicroRNA-31 (miR-31) is encoded on a genomic fragile site, 9p21.3, whi
Externí odkaz:
https://doaj.org/article/249850e64a7c42dbae37ac20ac59673a
Autor:
Laura Smith, Omar Qutob, Mark B. Watson, Andrew W. Beavis, Donna Potts, Kevin J. Welham, Veerabhadram Garimella, Michael J. Lind, Philip J. Drew, Lynn Cawkwell
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 11, Iss 11, Pp 1194-1207 (2009)
PURPOSE: We aimed to identify putative predictive protein biomarkers of radioresistance. EXPERIMENTAL DESIGN: Three breast cancer cell lines (MCF7, MDA-MB-231, and T47D) were used as in vitro models to study radioresistance. Inherent radiosensitiviti
Externí odkaz:
https://doaj.org/article/2db5ab3997264950808d2c40c380f002
Publikováno v:
Journal of Geriatric Oncology. 12:641-648
Background Older people with lung cancer are often frail and unfit due to their cancer and co-morbidities and may tolerate cancer treatments poorly. Physical activity (PA) and a healthy diet offer quality of life benefit to people with cancer before,
Autor:
Michael J. Lind, Sarah Greenley, Gordon McKenzie, Alex F. Bullock, Miriam J. Johnson, Mark Pearson
Publikováno v:
Journal of Geriatric Oncology. 12:22-33
Older adults with cancer are more likely to have worse clinical outcomes than their younger counterparts, and shared decision-making can be difficult, due to both complexity from adverse ageing and under-representation in clinical trials. Geriatric a
Autor:
Anne Campbell, Vijay Agarwal, Lynn Cawkwell, Stefan Laufer, Dulani Ranatunge, Michael J. Lind, Lily Oguh-Olayinka
Publikováno v:
Pathology Oncology Research
Advanced malignant pleural mesothelioma (MPM) has an extremely poor prognosis with limited chemotherapy options, therefore the identification of new therapeutic targets would aid in disease management. Arachidonic acid is metabolised by cyclooxygenas
Publikováno v:
Lung Cancer. 156:S38-S39
Autor:
Nicola de Liguori Carino, Kwok-Leung Cheung, Richard Simcock, Ruth M. Parks, Sarah Danson, Neil Bayman, Lynda Wyld, Fiammetta Ugolini, Eleri Davies, Gary J. Doherty, Anita Parbhoo, Malcolm W.R. Reed, Daniel Swinson, Kirsty Colquhoun, Juliet Wright, Tania Kalsi, Michael J. Lind, Anna Lewis, Pippa Corrie, Gordana Babic-Illamn, Eleanor Smith, Simone Basile, Cassandra Ng, John Moore, Zoe Merchant, Alastair Greystoke, Danielle Harari, Rob Morris, Rachel Jones, Jenna Morgan, Anthea Cree, R. Young, Kyle Crawford, Mark Baxter, Lisa Jane Rodgers, Fabio Gomes
Publikováno v:
ecancermedicalscience
The ageing population poses new challenges globally. Cancer care for older patients is one of these challenges, and it has a significant impact on societies. In the United Kingdom (UK), as the number of older cancer patients increases, the management
Publikováno v:
Novel insights into malignant pleural disease.
Introduction and objective Dysregulation of Mammalian target of rapamycin pathway has been shown in various cancers. Phosphorylated 70S6k is a vital downstream signalling protein of this pathway, dysregulation of this protein has also been linked to
Autor:
Michael J. Lind, Kathryn Date, Gillian Jackson, Daniel Harman, Miriam J. Johnson, Anthony Maraveyas, Rajarshi Roy, Rhian Gabe
Publikováno v:
Journal of Geriatric Oncology. 10:175-177
One of the primary risk factors in the development of cancer is older age. The demographic shift to an ageing population has given rise to an increased number of older patients with cancer. The extreme heterogeneity within this population renders app
Publikováno v:
Annals of Oncology. 31:S1439-S1440